Search Results - "Henigsberg, N"

Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms by Uher, R, Perlis, R H, Henigsberg, N, Zobel, A, Rietschel, M, Mors, O, Hauser, J, Dernovsek, M Z, Souery, D, Bajs, M, Maier, W, Aitchison, K J, Farmer, A, McGuffin, P

“…Symptom dimensions have not yet been comprehensively tested as predictors of the substantial heterogeneity in outcomes of antidepressant treatment in major…”
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Measuring depression: comparison and integration of three scales in the GENDEP study by Uher, R, Farmer, A, Maier, W, Rietschel, M, Hauser, J, Marusic, A, Mors, O, Elkin, A, Williamson, R J, Schmael, C, Henigsberg, N, Perez, J, Mendlewicz, J, Janzing, J G E, Zobel, A, Skibinska, M, Kozel, D, Stamp, A S, Bajs, M, Placentino, A, Barreto, M, McGuffin, P, Aitchison, K J

“…A number of scales are used to estimate the severity of depression. However, differences between self-report and clinician rating, multi-dimensionality and…”
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Trajectories of change in depression severity during treatment with antidepressants by Uher, R, Muthén, B, Souery, D, Mors, O, Jaracz, J, Placentino, A, Petrovic, A, Zobel, A, Henigsberg, N, Rietschel, M, Aitchison, K J, Farmer, A, McGuffin, P

“…Response and remission defined by cut-off values on the last observed depression severity score are commonly used as outcome criteria in clinical trials, but…”
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Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project by Perroud, N, Uher, R, Ng, M Y M, Guipponi, M, Hauser, J, Henigsberg, N, Maier, W, Mors, O, Gennarelli, M, Rietschel, M, Souery, D, Dernovsek, M Z, Stamp, A S, Lathrop, M, Farmer, A, Breen, G, Aitchison, K J, Lewis, C M, Craig, I W, McGuffin, P

“…Suicidal thoughts during antidepressant treatment have been the focus of several candidate gene association studies. The aim of the present genome-wide…”
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New insights into the pharmacogenomics of antidepressant response from the GENDEP and STARD studies: rare variant analysis and high-density imputation by Fabbri, C, Tansey, K E, Perlis, R H, Hauser, J, Henigsberg, N, Maier, W, Mors, O, Placentino, A, Rietschel, M, Souery, D, Breen, G, Curtis, C, Sang-Hyuk, L, Newhouse, S, Patel, H, Guipponi, M, Perroud, N, Bondolfi, G, O'Donovan, M, Lewis, G, Biernacka, J M, Weinshilboum, R M, Farmer, A, Aitchison, K J, Craig, I, McGuffin, P, Uher, R, Lewis, C M

“…Genome-wide association studies have generally failed to identify polymorphisms associated with antidepressant response. Possible reasons include limited…”
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Serotonin transporter gene polymorphisms: Relation with platelet serotonin level in patients with primary Sjogren's syndrome by Markeljevic, J, Sarac, H, Bozina, N, Henigsberg, N, Simic, M, Cicin Sain, L

“…Abstract Significantly lower platelet serotonin level (PSL) in patients with primary Sjogren's syndrome (pSS) than in healthy controls has been reported in our…”
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Non-steroidal anti-inflammatory drugs and efficacy of antidepressants in major depressive disorder by Uher, R, Carver, S, Power, R A, Mors, O, Maier, W, Rietschel, M, Hauser, J, Dernovsek, M Z, Henigsberg, N, Souery, D, Placentino, A, Farmer, A, McGuffin, P

“…It has been proposed that non-steroidal anti-inflammatory drugs (NSAIDs) may interfere with the efficacy of antidepressants and contribute to treatment…”
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Familiality and SNP heritability of age at onset and episodicity in major depressive disorder by Ferentinos, P, Koukounari, A, Power, R, Rivera, M, Uher, R, Craddock, N, Owen, M J, Korszun, A, Jones, L, Jones, I, Gill, M, Rice, J P, Ising, M, Maier, W, Mors, O, Rietschel, M, Preisig, M, Binder, E B, Aitchison, K J, Mendlewicz, J, Souery, D, Hauser, J, Henigsberg, N, Breen, G, Craig, I W, Farmer, A E, Müller-Myhsok, B, McGuffin, P, Lewis, C M

“…Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO)…”
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Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project by Keers, R, Uher, R, Huezo-Diaz, P, Smith, R, Jaffee, S, Rietschel, M, Henigsberg, N, Kozel, D, Mors, O, Maier, W, Zobel, A, Hauser, J, Souery, D, Placentino, A, Larsen, E R, Dmitrzak-Weglarz, M, Gupta, B, Hoda, F, Craig, I, McGuffin, P, Farmer, A E, Aitchison, K J

“…There is substantial inter-individual variation in response to antidepressants, and genetic variation may, in part, explain these differences. For example,…”
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Copy number variants and therapeutic response to antidepressant medication in major depressive disorder by Tansey, K E, Rucker, J J H, Kavanagh, D H, Guipponi, M, Perroud, N, Bondolfi, G, Domenici, E, Evans, D M, Hauser, J, Henigsberg, N, Jerman, B, Maier, W, Mors, O, O'Donovan, M, Peters, T J, Placentino, A, Rietschel, M, Souery, D, Aitchison, K J, Craig, I, Farmer, A, Wendland, J R, Malafosse, A, Lewis, G, Kapur, S, McGuffin, P, Uher, R

“…It would be beneficial to find genetic predictors of antidepressant response to help personalise treatment of major depressive disorder (MDD). Rare copy number…”
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Investigation of blood mRNA biomarkers for suicidality in an independent sample by Mullins, N, Hodgson, K, Tansey, K E, Perroud, N, Maier, W, Mors, O, Rietschel, M, Hauser, J, Henigsberg, N, Souery, D, Aitchison, K, Farmer, A, McGuffin, P, Breen, G, Uher, R, Lewis, C M

“…Changes in the blood expression levels of SAT1, PTEN, MAP3K3 and MARCKS genes have been reported as biomarkers of high versus low suicidality state…”
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P.2.c.018 Efficacy and tolerability of multiple doses of LU AA21004 in an 8-week trial of adults with major depressive disorder by Henigsberg, N, Mahableshwarkar, A, Jacobsen, P, Chen, Y, Thase, M.E

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P.3.002 Informative dropout and the relative efficacy of escitalopram and nortriptyline in treating major depressive disorder by Power, R, Muthén, B, Henigsberg, N, Mors, O, Placentino, A, Mendlewicz, J, Maier, W, McGuffin, P, Lewis, C.M, Uher, R

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P.3.13 Temperament and character of subjects with treatment increase suicidal ideations in the GENDEP study by Perroud, N, Uher, R, Maier, W, Mors, O, Henigsberg, N, Rietschel, M, Hauser, J, Farmer, A.E, Aitchison, K.J, McGuffin, P

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P.3.16 Characterisation of response to antidepressants in a pharmacogenetic trial by Uher, R, Maier, W, Rietschel, M, Hauser, J, Mors, O, Marusic, A, Henigsberg, N, Perez, J, Mendlewicz, J, McGuffin, P

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Stressor characteristics and post-traumatic stress disorder symptom dimensions in war victims by Henigsberg, N, Folnegović-Smalc, V, Moro, L

“…To evaluate how the type of trauma is related to specific symptom patterns in patients with post-traumatic stress disorder (PTSD) according to the Diagnostic…”
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A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression by Wei, Ya Bin, McCarthy, Michael, Ren, Hongyan, Carrillo-Roa, Tania, Shekhtman, Tatyana, DeModena, Anna, Liu, Jia Jia, Leckband, Susan G., Mors, Ole, Rietschel, Marcella, Henigsberg, Neven, Cattaneo, Annamaria, Binder, Elisabeth B., Aitchison, Katherine J., Kelsoe, John R.

“…Predicting antidepressant response has been a clinical challenge for mood disorder. Although several genome-wide association studies have suggested a number of…”
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Catatonic schizophrenia has a shorter pre-hospitalisation interval than other types of schizophrenia by MIMICA, N, HENIGSBERG, N, UZUN, S, LJUBIN, T, FOLNEGOVIC, Z, FOLNEGOVIC-SMALC, V

“…The time elapsed between the first onset of symptoms and the onset of first hospitalisation was analysed in 355 participants diagnosed with paranoid, simple,…”
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Meta-analysis of CYP2C19 association with efficacy and side effects of citalopram and escitalopram by Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O’Donovan, M., Lewis, G., Biernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R., Lewis, C.

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P.1.a.009 - Meta-analysis of CYP2C19 association with efficacy and side effects of citalopram and escitalopram by Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O’Donovan, M., Lewis, G., Biernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R., Lewis, C.

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