Search Results - "Henics, Tamás"

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies by Giefing, Carmen, Meinke, Andreas L, Hanner, Markus, Henics, Tamás, Bui, Minh Duc, Gelbmann, Dieter, Lundberg, Urban, Senn, Beatrice M, Schunn, Michael, Habel, Andre, Henriques-Normark, Birgitta, Ortqvist, Ake, Kalin, Mats, von Gabain, Alexander, Nagy, Eszter

“…Pneumococcus is one of the most important human pathogens that causes life-threatening invasive diseases, especially at the extremities of age. Capsular…”
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Novel Conserved Group A Streptococcal Proteins Identified by the Antigenome Technology as Vaccine Candidates for a Non-M Protein-Based Vaccine by Fritzer, Andrea, Senn, Beatrice M, Minh, Duc Bui, Hanner, Markus, Gelbmann, Dieter, Noiges, Birgit, Henics, Tamás, Schulze, Kai, Guzman, Carlos A, Goodacre, John, von Gabain, Alexander, Nagy, Eszter, Meinke, Andreas L

“…Group A streptococci (GAS) can cause a wide variety of human infections ranging from asymptomatic colonization to life-threatening invasive diseases. Although…”
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Evaluation of the Safety, Tolerability and Immunogenicity of ShigETEC, an Oral Live Attenuated Shigella -ETEC Vaccine in Placebo-Controlled Randomized Phase 1 Trial by Girardi, Petra, Harutyunyan, Shushan, Neuhauser, Irene, Glaninger, Katharina, Korda, Orsolya, Nagy, Gábor, Nagy, Eszter, Szijártó, Valéria, Pall, Denes, Szarka, Krisztina, Kardos, Gábor, Henics, Tamás, Malinoski, Frank J

“…spp. and enterotoxigenic (ETEC) cause high morbidity and mortality worldwide, yet no licensed vaccines are available to prevent corresponding infections. A…”
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Comparison of antibody repertoires against Staphylococcus aureus in healthy individuals and in acutely infected patients by Dryla, Agnieszka, Prustomersky, Sonja, Gelbmann, Dieter, Hanner, Markus, Bettinger, Edith, Kocsis, Béla, Kustos, Tamás, Henics, Tamás, Meinke, Andreas, Nagy, Eszter

“…The management of staphylococcal diseases is increasingly difficult with present medical approaches. Preventive and therapeutic vaccination is considered to be…”
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Adjuvating the adjuvant: Facilitated delivery of an immunomodulatory oligonucleotide to TLR9 by a cationic antimicrobial peptide in dendritic cells by Aichinger, Michael C, Ginzler, Michael, Weghuber, Julian, Zimmermann, Lars, Riedl, Karin, Schütz, Gerhard, Nagy, Eszter, von Gabain, Alexander, Schweyen, Rudolf, Henics, Tamás

“…Abstract IC31® is a novel bi-component vaccine adjuvant consisting of the peptide KLKL5 KLK (KLK) and the TLR9 agonist oligonucleotide d(IC)13 (ODN1a). While…”
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Immunological fingerprinting of group B streptococci: From circulating human antibodies to protective antigens by Meinke, Andreas L, Senn, Beatrice M, Visram, Zehra, Henics, Tamás Z, Minh, Duc Bui, Schüler, Wolfgang, Neubauer, Christina, Gelbmann, Dieter, Noiges, Birgit, Sinzinger, Jan, Hanner, Markus, Dewasthaly, Shailesh, Lundberg, Urban, Hordnes, Knut, Masoud, Helga, Sevelda, Paul, von Gabain, Alexander, Nagy, Eszter

“…Abstract Group B streptococcus is one of the most important pathogens in neonates, and causes invasive infections in non-pregnant adults with underlying…”
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Identification of in vivo Expressed Vaccine Candidate Antigens from Staphylococcus aureus by Etz, Hildegard, Minh, Duc Bui, Henics, Tamás, Dryla, Agnieszka, Winkler, Birgit, Triska, Christine, Boyd, Aoife P., Söllner, Johannes, Schmidt, Walter, von Ahsen, Uwe, Buschle, Michael, Gill, Steven R., Kolonay, James, Khalak, Hanif, Fraser, Claire M., von Gabain, Alexander, Nagy, Eszter, Meinke, Andreas

“…For the design of potent subunit vaccines, it is of paramount importance to identify all antigens immunologically recognized by a patient population infected…”
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Cationic amphipathic peptides accumulate sialylated proteins and lipids in the plasma membrane of eukaryotic host cells by Weghuber, Julian, Aichinger, Michael C., Brameshuber, Mario, Wieser, Stefan, Ruprecht, Verena, Plochberger, Birgit, Madl, Josef, Horner, Andreas, Reipert, Siegfried, Lohner, Karl, Henics, Tamás, Schütz, Gerhard J.

“…Cationic antimicrobial peptides (CAMPs) selectively target bacterial membranes by electrostatic interactions with negatively charged lipids. It turned out that…”
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Cytoplasmic vacuolation, adaptation and cell death: A view on new perspectives and features by Henics, Tamás, Wheatley, Denys N

“…This review focuses on a widely-observed morphological phenomenon, a unique class of cytoplasmic vacuolation, found in cultured (mammalian) cells. This…”
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Composition of the ANTIGENome of Helicobacter pylori defined by human serum antibodies by Meinke, Andreas, Storm, Martin, Henics, Tamás, Gelbmann, Dieter, Prustomersky, Sonja, Kovács, Zoltán, Minh, Duc Bui, Noiges, Birgit, Stierschneider, Ulrike, Berger, Manfred, von Gabain, Alexander, Engstrand, Lars, Nagy, Eszter

“…Abstract Helicobacter pylori is the most prevalent human pathogen and although, it remains silent in most individuals for lifetime, colonization may develop…”
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Mammalian Hsp70 and Hsp110 Proteins Bind to RNA Motifs Involved in mRNA Stability by Henics, T, Nagy, E, Oh, H J, Csermely, P, von Gabain, A, Subjeck, J R

“…In this study, in vitro RNA binding by members of the mammalian 70-kDa heat shock protein (Hsp) family was examined. We show that Hsp/Hsc70 and Hsp110 proteins…”
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Identification of the NAD+-Binding Fold of Glyceraldehyde-3-Phosphate Dehydrogenase as a Novel RNA-Binding Domain by Nagy, Eszter, Henics, Tamás, Eckert, Mária, Miseta, Attila, Lightowlers, Robert N., Kellermayer, Miklós

“…There is growing evidence that metabolic enzymes may act as multifunctional proteins performing diverse roles in cellular metabolism. Among these functions are…”
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Antimicrobial and immunostimulatory peptide, KLK, induces an increase in cytosolic Ca2+ concentration by mobilizing Ca2+ from intracellular stores by Weghuber, Julian, Lipp, Anna M., Stadlbauer, Jacqueline, Aichinger, Michael C., Ruprecht, Verena, Sonnleitner, Alois, Schütz, Gerhard J., Henics, Tamás

“…The cationic antimicrobial immunomodulatory peptide, KLK (KLKL5KLK), exerts profound membrane interacting properties, impacting on ultrastructure and fluidity…”
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Characterization of ShigETEC, a Novel Live Attenuated Combined Vaccine against Shigellae and ETEC by Harutyunyan, Shushan, Neuhauser, Irene, Mayer, Alexandra, Aichinger, Michael, Szijártó, Valéria, Nagy, Gábor, Nagy, Eszter, Girardi, Petra, Malinoski, Frank J, Henics, Tamás

“…: spp. and enterotoxigenic (ETEC) remain the two leading bacterial causes of diarrheal diseases worldwide. Attempts to develop preventive vaccines against…”
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Anti-Toxin Responses to Natural Enterotoxigenic Escherichia coli (ETEC) Infection in Adults and Children in Bangladesh by Girardi, Petra, Bhuiyan, Taufiqur Rahman, Lundin, Samuel B., Harutyunyan, Shushan, Neuhauser, Irene, Khanam, Farhana, Nagy, Gábor, Szijártó, Valéria, Henics, Tamás, Nagy, Eszter, Harandi, Ali M., Qadri, Firdausi

“…A sero-epidemiology study was conducted in Dhaka, Bangladesh between January 2020 and February 2021 to assess the immune responses to ETEC infection in adults…”
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Functional Selection of Vaccine Candidate Peptides from Staphylococcus aureus Whole-Genome Expression Libraries In Vitro by WEICHHART, Thomas, HORKY, Markus, HAFNER, Martin, VON AHSEN, Uwe, SÖLLNER, Johannes, GANGL, Susanne, HENICS, Tamas, NAGY, Eszter, MEINKE, Andreas, VON GABAIN, Alexander, FRASER, Claire M, GILL, Steve R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antigenome technology: a novel approach for the selection of bacterial vaccine candidate antigens by Meinke, Andreas, Henics, Tamás, Hanner, Markus, Minh, Duc Bui, Nagy, Eszter

“…A novel approach for the identification of protein antigens from bacterial pathogens was previously developed in our laboratory that combines the advantages of…”
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Anti-Toxin Responses to Natural Enterotoxigenic IEscherichia coli/I Infection in Adults and Children in Bangladesh by Girardi, Petra, Bhuiyan, Taufiqur Rahman, Lundin, Samuel B, Harutyunyan, Shushan, Neuhauser, Irene, Khanam, Farhana, Nagy, Gábor, Szijártó, Valéria, Henics, Tamás, Nagy, Eszter, Harandi, Ali M, Qadri, Firdausi

“…A sero-epidemiology study was conducted in Dhaka, Bangladesh between January 2020 and February 2021 to assess the immune responses to ETEC infection in adults…”
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Unique membrane-interacting properties of the immunostimulatory cationic peptide KLKL(5)KLK (KLK) by Aichinger, Michael C, Ortbauer, Martina, Reipert, Siegfried, Zauner, Wolfgang, Bogner, Péter, Froschauer, Elisabeth, Nowikovsky, Karin, Lingnau, Karen, von Gabain, Alexander, Schweyen, Rudolf, Henics, Tamás

“…We have monitored the effects of KLKL(5)KLK (KLK), a derivative of a natural cationic antimicrobial peptide (CAP) on isolated membrane vesicles, and…”
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Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues by Sun, X, Li, X, Moriarty, P M, Henics, T, LaDuca, J P, Maquat, L E

“…Previous studies of mRNA for classical glutathione peroxidase 1 (GPx1) demonstrated that hepatocytes of rats fed a selenium-deficient diet have less…”
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