Search Results - "Heng, Xingyu"
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Glycopolymers for Antibacterial and Antiviral Applications
Published in Molecules (Basel, Switzerland) (18-01-2023)“…Diseases induced by bacterial and viral infections are common occurrences in our daily life, and the main prevention and treatment strategies are vaccination…”
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Dendritic cells maturation facilitated by group-adjustable lipopolysaccharide analogues synthesized via RAFT polymerization
Published in Chinese chemical letters (01-09-2022)“…Transforming immature DCs into mature state to activate cellular immunity is a critical step in initiating immunoprophylaxis and immunotherapy…”
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Immune Effect Regulated by the Chain Length: Interaction between Immune Cell Surface Receptors and Synthetic Glycopolymers
Published in ACS applied materials & interfaces (11-08-2021)“…Glycopolymer-based drugs for immunotherapy have attracted increasing attention because the affinity between glycans and proteins plays an important role in…”
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Customizable Glycopolymers as Adjuvants for Cancer Immunotherapy: From Branching Degree Optimization to Cell Surface Engineering
Published in Biomacromolecules (13-11-2024)“…Engineering dendritic cell (DC) maturation is paramount for robust T-cell responses and immunological memory, critical for cancer immunotherapy. This work…”
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Synthetic Sugar-Only Polymers with Double-Shoulder Task: Bioactivity and Imaging
Published in Biomacromolecules (14-03-2022)“…The search for novel fluorescent materials has attracted the attention of many researchers. Numerous bioimaging materials based on the aggregation-induced…”
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Integrating Metabolic Oligosaccharide Engineering and SPAAC Click Chemistry for Constructing Fibrinolytic Cell Surfaces
Published in ACS applied materials & interfaces (17-07-2024)“…To effectively solve the problem of significant loss of transplanted cells caused by thrombosis during cell transplantation, this study simulates the human…”
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Click‐Chemistry‐Mediated Cell Membrane Glycopolymer Engineering to Potentiate Dendritic Cell Vaccines
Published in Angewandte Chemie International Edition (08-01-2024)“…Dendritic cell vaccine (DCV) holds great potential in tumor immunotherapy owing to its potent ability in eliciting tumor‐specific immune responses. Aiming at…”
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Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro‐Adjuvants for Dendritic Cell Vaccine
Published in Angewandte Chemie International Edition (10-06-2024)“…In the development of dendritic cell (DC) vaccines, the maturation of DCs is a critical stage. Adjuvants play a pivotal role in the maturation of DCs, with a…”
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Well-Defined Oligo(azobenzene-graft-mannose): Photostimuli Supramolecular Self-Assembly and Immune Effect Regulation
Published in ACS macro letters (19-03-2024)“…The immune system can recognize and respond to pathogens of various shapes. Synthetic materials that can change their shape have the potential to be used in…”
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Glycopolymers With On/Off Anchors: Confinement Effect on Regulating Dendritic Cells
Published in Advanced healthcare materials (01-11-2023)“…Abstract Insufficient activation or over‐activation of T cells due to the dendritic cells (DCs) state can cause negative effects on immunotherapy, making it…”
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Cell surface functionalization with lysine ligand-containing copolymers for fibrinolytic activity
Published in Materials advances (02-01-2024)“…Although cell transplantation has achieved great success in the treatment of many intractable diseases, due to the effect of an instant blood-mediated…”
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Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro‐Adjuvants for Dendritic Cell Vaccine
Published in Angewandte Chemie (10-06-2024)“…In the development of dendritic cell (DC) vaccines, the maturation of DCs is a critical stage. Adjuvants play a pivotal role in the maturation of DCs, with a…”
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Click‐Chemistry‐Mediated Cell Membrane Glycopolymer Engineering to Potentiate Dendritic Cell Vaccines
Published in Angewandte Chemie (08-01-2024)“…Dendritic cell vaccine (DCV) holds great potential in tumor immunotherapy owing to its potent ability in eliciting tumor‐specific immune responses. Aiming at…”
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High-Efficiency Bactericidal and Biofilm Elimination Ability of the Biodegradable Alternating Sequence Main-Chain Polyselenium Salt
Published in ACS applied polymer materials (10-05-2024)“…Bacterial drug resistance and biofilm adhesion present substantial challenges for both economic development and human health and safety. Consequently, the…”
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