Search Results - "Heng, Kathleen"
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Development of a novel SupraChoroidal-to-Optic-NervE (SCONE) drug delivery system
Published in Drug delivery (01-12-2024)“…Targeted drug delivery to the optic nerve head may be useful in the preclinical study and later clinical management of optic neuropathies, however, there are…”
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Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system
Published in Developmental dynamics (01-02-2012)“…Background: Tbx2, Tbx3, Tbx4, and Tbx5, members of the Tbx2 subfamily of T‐box transcription factor genes, are important for many aspects of embryonic…”
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High‐dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-09-2013)“…Summary Purpose The role of granule cell axon (mossy fiber) sprouting in temporal lobe epileptogenesis is unclear and controversial. Rapamycin suppresses mossy…”
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Increased ER Stress After Experimental Ischemic Optic Neuropathy and Improved RGC and Oligodendrocyte Survival After Treatment With Chemical Chaperon
Published in Investigative ophthalmology & visual science (01-05-2019)“…Increased endoplasmic reticulum (ER) stress is one of the earliest subcellular changes in neuro-ophthalmic diseases. In this study, we investigated the…”
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Continuous Rate Infusion of Alfaxalone during Ketamine-Xylazine Anesthesia in Rats
Published in Journal of the American Association for Laboratory Animal Science (01-03-2020)“…Alfaxalone is an injectable anesthetic agent that is used in veterinary medicine for general anesthesia. We evaluated the safety and efficacy of alfaxalone…”
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The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo
Published in Nature methods (01-01-2024)“…Multiphoton microscopy can resolve fluorescent structures and dynamics deep in scattering tissue and has transformed neural imaging, but applying this…”
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BDNF and cAMP are neuroprotective in a porcine model of traumatic optic neuropathy
Published in JCI insight (08-02-2024)“…Traumatic optic neuropathy (TON) is a devastating condition that can occur after blunt or penetrating trauma to the head, leading to visual impairment or…”
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Dose Regimens, Variability, and Complications Associated with Using Repeat-Bolus Dosing to Extend a Surgical Plane of Anesthesia in Laboratory Mice
Published in Journal of the American Association for Laboratory Animal Science (01-11-2014)“…Extending a surgical plane of anesthesia in mice by using injectable anesthetics typically is accomplished by repeat-bolus dosing. We compared the safety and…”
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Three cheers for the three-spined stickleback
Published in Lab animal (20-10-2016)Get full text
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