Search Results - "Heng, H."

The Spiral Model of Evolution: Stable Life Forms of Organisms and Unstable Life Forms of Cancers by Kasperski, Andrzej, Heng, Henry H

“…If one must prioritize among the vast array of contributing factors to cancer evolution, environmental-stress-mediated chromosome instability (CIN) should…”
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Transient and stable vector transfection: Pitfalls, off-target effects, artifacts by Stepanenko, Aleksei A., Heng, Henry H.

“…[Display omitted] Transient and stable vector transfections have played important roles in illustrating the function of specific genes/proteins. The general…”
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Karyotype coding: The creation and maintenance of system information for complexity and biodiversity by Heng, Julie, Heng, Henry H.

“…The mechanism of biological information flow is of vital importance. However, traditional research surrounding the genetic code that follows the central dogma…”
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Further illusions: On key evolutionary mechanisms that could never fit with Modern Synthesis by Crkvenjakov, Radomir, Heng, Henry H.

“…In light of illusions of the Modern Synthesis (MS) listed by Noble (2021a), MS's key concept, that gradual accumulation of gene mutations within microevolution…”
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The effect of aspect ratio on the aerodynamic forces and bending moment for a surface-mounted finite-height cylinder by Beitel, A., Heng, H., Sumner, D.

“…Wind tunnel experiments were performed at Re = 6.5 × 104 to measure the mean drag and normal forces, mean bending moment, and vortex shedding frequency for…”
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Antioxidant action and effectiveness of sulfur-containing amino acid during deep frying by Heng, H. F. Emilie, Ong, X. L., Chow, P. Y. Edwin

“…The aim of the study was to solve the mystery why sulfur-containing amino acids such as methionine can perform as an antioxidant during frying and hypothesized…”
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Editorial: Somatic genomic mosaicism & human disease by Iourov, Ivan Y., Heng, Henry H.

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Origins and Consequences of Chromosomal Instability: From Cellular Adaptation to Genome Chaos-Mediated System Survival by Ye, Christine J, Sharpe, Zachary, Heng, Henry H

“…When discussing chromosomal instability, most of the literature focuses on the characterization of individual molecular mechanisms. These studies search for…”
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What Is Karyotype Coding and Why Is Genomic Topology Important for Cancer and Evolution? by Ye, Christine J., Stilgenbauer, Lukas, Moy, Amanda, Liu, Guo, Heng, Henry H.

“…While the importance of chromosomal/nuclear variations vs. gene mutations in diseases is becoming more appreciated, less is known about its genomic basis…”
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Genetic and epigenetic heterogeneity in cancer: the ultimate challenge for drug therapy by Heng, H H, Liu, G, Stevens, J B, Bremer, S W, Ye, K J, Ye, C J

“…Based on the gene and pathway centric concept of cancer, current approaches to cancer drug treatment have been focused on key molecular targets specific and…”
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Chemokine-Driven Migration of Pro-Inflammatory CD4 + T Cells in CNS Autoimmune Disease by Heng, Aaron H S, Han, Caleb W, Abbott, Caitlin, McColl, Shaun R, Comerford, Iain

“…Pro-inflammatory CD4 T helper (Th) cells drive the pathogenesis of many autoimmune conditions. Recent advances have modified views of the phenotype of…”
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Distinguishing constitutional and acquired nonclonal aneuploidy by Heng, Henry H

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Effects of glycerol on enzymatic hydrolysis and ethanol production using sugarcane bagasse pretreated by acidified glycerol solution by Zhang, Zhanying, Wong, Heng H., Albertson, Peter L., Harrison, Mark D., Doherty, William O.S., O’Hara, Ian M.

“…•2.0wt% glycerol inhibited glucan digestibility by 2.0%.•Up to 5.0wt% glycerol had no effect on subsequent yeast fermentation.•Glycerol is a less potent…”
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The Conflict Between Complex Systems and Reductionism by Heng, Henry H. Q

“…Heng analyzes the conflict between reductionism and complex systems. With increasing technological capabilities, these systems can be examined in continuously…”
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Stress, genomic adaptation, and the evolutionary trade-off by Horne, Steven D, Chowdhury, Saroj K, Heng, Henry H Q

“…Cells are constantly exposed to various internal and external stresses. The importance of cellular stress and its implication to disease conditions have become…”
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Somatic Genomic Mosaicism in Multiple Myeloma by Ye, Christine J, Chen, Jason, Liu, Guo, Heng, Henry H

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Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing by Becherel, Olivier J, Yeo, Abrey J, Stellati, Alissa, Heng, Evelyn Y H, Luff, John, Suraweera, Amila M, Woods, Rick, Fleming, Jean, Carrie, Dianne, McKinney, Kristine, Xu, Xiaoling, Deng, Chuxia, Lavin, Martin F

“…Senataxin, mutated in the human genetic disorder ataxia with oculomotor apraxia type 2 (AOA2), plays an important role in maintaining genome integrity by…”
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Karyotype heterogeneity and unclassified chromosomal abnormalities by Heng, H H Q, Liu, G, Stevens, J B, Abdallah, B Y, Horne, S D, Ye, K J, Bremer, S W, Chowdhury, S K, Ye, C J

“…In a departure from traditional gene-centric thinking with regard to cytogenetics and cytogenomics, the recently introduced genome theory calls upon a…”
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Epidermoid cysts associated with the gastrointestinal tract in a dog by Ogden, J. A., Heng, H. G., Ramos‐Vara, J. A.

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Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems by Ye, Christine J, Regan, Sarah, Liu, Guo, Alemara, Sarah, Heng, Henry H

“…In the past 15 years, impressive progress has been made to understand the molecular mechanism behind aneuploidy, largely due to the effort of using various…”
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