Search Results - "Hendy, Ayman"

Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF‐β3 and Wnt/β‐Catenin pathways by Afrin, Sadia, Ali, Mohamed, El Sabeh, Malak, Yang, Qiwei, Al‐Hendy, Ayman, Borahay, Mostafa A.

“…Uterine leiomyoma (UL) is the most common gynaecologic tumour, affecting an estimated 70 to 80% of women. Leiomyomas develop from the transformation of…”
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Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy by Borahay, Mostafa A, Al-Hendy, Ayman, Kilic, Gokhan S, Boehning, Darren

“…Uterine leiomyomas are the most common tumors of the female genital tract, affecting 50% to 70% of females by the age of 50. Despite their prevalence and…”
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Role of vitamin D in uterine fibroid biology by Brakta, Soumia, M.D, Diamond, Justin S., B.S, Al-Hendy, Ayman, M.D., Ph.D, Diamond, Michael P., M.D, Halder, Sunil K., Ph.D

“…Objective To provide a detailed summary of current scientific knowledge on uterine fibroids (leiomyomas) in vitro and in in vivo animal models, as well as to…”
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Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis by Mas, Aymara, Stone, Leyland, O'Connor, Paul M., Yang, Qiwei, Kleven, Daniel, Simon, Carlos, Walker, Cheryl L., Al‐Hendy, Ayman

“…Despite the high prevalence and major negative impact of uterine fibroids (UFs) on women's health, their pathogenesis remains largely unknown. While…”
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Quality of life improvements in women with uterine fibroids treated with relugolix combination therapy during the LIBERTY long‐term extension study: A descriptive subgroup analysis in women with anemia at baseline by Venturella, Roberta, Lukes, Andrea S., Wu, Rui, McLean, Rachel, Rakov, Viatcheslav G., Al‐Hendy, Ayman

“…Objective To investigate the effects of 52 weeks of treatment with relugolix combination therapy (relugolix 40 mg, estradiol 1 mg, norethindrone acetate 0.5…”
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Cardiac Surgery and the Blood-Brain Barrier by Hendy, Ayman, Hall, Richard

“…Neurologic abnormality after cardiac surgery is common, and neurologic complications after cardiac surgery are among the most devastating problems that can…”
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Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol- O -methyltransferase by Sharan, Chakradhari, Ph.D, Halder, Sunil K., Ph.D, Thota, Chandrasekhar, Ph.D, Jaleel, Tarannum, Nair, Sangeeta, D.V.M., M.Sc, Al-Hendy, Ayman, M.D., Ph.D

“…Objective To evaluate the effects and mechanisms of action of vitamin D on human uterine leiomyoma (HuLM) cell proliferation in vitro. Design Laboratory study…”
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Hypovitaminosis D and high serum transforming growth factor beta-3: important biomarkers for uterine fibroids risk by Halder, Sunil, Ph.D, Al-Hendy, Ayman, M.D., Ph.D

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Update on the Role and Regulatory Mechanism of Extracellular Matrix in the Pathogenesis of Uterine Fibroids by Yang, Qiwei, Al-Hendy, Ayman

“…Uterine fibroids (UFs), also known as leiomyomas, are benign tumors of the myometrium affecting over 70% of women worldwide, particularly women of color…”
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Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women by Ali, Mohamed, A R, Sara, Al Hendy, Ayman

“…Uterine fibroids (UFs) are the most common benign tumor arising from myometrium of reproductive age women, with significant financial burden estimated in…”
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The Functional Role and Regulatory Mechanism of FTO m6A RNA Demethylase in Human Uterine Leiomyosarcoma by Yang, Qiwei, Al-Hendy, Ayman

“…Uterine leiomyosarcoma (uLMS) is the most frequent subtype of uterine sarcoma that presents a poor prognosis and high rates of recurrence and metastasis. The…”
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Endocrine-disrupting chemicals and uterine fibroids by Katz, Tiffany A., Ph.D, Yang, Qiwei, Ph.D, Treviño, Lindsey S., Ph.D, Walker, Cheryl L., Ph.D, Al-Hendy, Ayman, M.D., Ph.D

“…Uterine fibroids are the most frequent gynecologic tumor, affecting 70% to 80% of women over their lifetime. Although these tumors are benign, they can cause…”
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Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor-initiating stem cells by Shalaby, Shahinaz Mahmood, M.D., M.Sc, Khater, Mostafa K., Pharm.D., M.Sc, Perucho, Aymara Mas, Ph.D, Mohamed, Sara A., M.D., M.Sc, Helwa, Inas, Ph.D, Laknaur, Archana, M.Sc, Lebedyeva, Iryna, Ph.D, Liu, Yutao, Ph.D, Diamond, Michael P., M.D, Al-Hendy, Ayman A., M.D., Ph.D

“…Objective To study whether efficient transduction and subsequent elimination of fibroid tumor-initiating stem cells during debulking of tumor cells will aid in…”
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Stro-1/CD44 as putative human myometrial and fibroid stem cell markers by Mas, Aymara, Ph.D, Nair, Sangeeta, D.V.M., M.S, Laknaur, Archana, M.S, Simón, Carlos, M.D., Ph.D, Diamond, Michael P., M.D, Al-Hendy, Ayman, M.D., Ph.D

“…Objective To identify and characterize myometrial/fibroid stem cells by specific stem cell markers in human myometrium, and to better understand the stem cell…”
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Stem Cell Therapy: From Idea to Clinical Practice by Mousaei Ghasroldasht, Mohammad, Seok, Jin, Park, Hang-Soo, Liakath Ali, Farzana Begum, Al-Hendy, Ayman

“…Regenerative medicine is a new and promising mode of therapy for patients who have limited or no other options for the treatment of their illness. Due to their…”
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The Regulatory Functions and the Mechanisms of Long Non-Coding RNAs in Cervical Cancer by Yang, Qiwei, Al-Hendy, Ayman

“…Cervical cancer is one of the leading causes of death in gynecology cancer worldwide. High-risk human papillomaviruses (HPVs) are the major etiological agents…”
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Berberine inhibits the proliferation of human uterine leiomyoma cells by Wu, Hsiao-Li, M.S., M.B.A, Chuang, Tung-Yueh, Ph.D, Al-Hendy, Ayman, M.D., Ph.D, Diamond, Michael P., M.D, Azziz, Ricardo, M.D., M.B.A., M.P.H, Chen, Yen-Hao, Ph.D

“…Objective To determine whether berberine (BBR), a naturally occurring plant-derived alkaloid, inhibits the proliferation of human uterine leiomyoma (UtLM)…”
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Exosomes as Biomarkers for Female Reproductive Diseases Diagnosis and Therapy by Esfandyari, Sahar, Elkafas, Hoda, Chugh, Rishi Man, Park, Hang-Soo, Navarro, Antonia, Al-Hendy, Ayman

“…Cell-cell communication is an essential mechanism for the maintenance and development of various organs, including the female reproductive system. Today, it is…”
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Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study by Borahay, Mostafa A., MD, PhD, Vincent, Kathleen, MD, Motamedi, Massoud, PhD, Sbrana, Elena, PhD, Kilic, Gokhan S., MD, Al-Hendy, Ayman, MD, PhD, Boehning, Darren, PhD

“…Objective Uterine leiomyomas represent a common gynecologic problem with no satisfactory long-term medical treatment. The purpose of this study is to examine…”
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The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice by Lu, Fangxian, MD, Longo, Monica, MD, PhD, Tamayo, Esther, Maner, William, BS, Al-Hendy, Ayman, MD, PhD, Anderson, Garland D., MD, Hankins, Gary D.V., MD, Saade, George R., MD

“…Objective It has been shown that the level of soluble fms-like tyrosine kinase–1 (sFlt-1) is elevated in pregnant women who are destined to have preeclampsia,…”
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