Search Results - "Hendrychova, Tereza"

Membrane Position of Ibuprofen Agrees with Suggested Access Path Entrance to Cytochrome P450 2C9 Active Site by Berka, Karel, Hendrychová, Tereza, Anzenbacher, Pavel, Otyepka, Michal

“…Cytochrome P450 2C9 (CYP2C9) is a membrane-anchored human microsomal protein involved in the drug metabolism in liver. CYP2C9 consists of an N-terminal…”
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Dynamics and hydration of the active sites of mammalian cytochromes P450 probed by molecular dynamics simulations by Hendrychova, Tereza, Berka, Karel, Navratilova, Veronika, Anzenbacher, Pavel, Otyepka, Michal

“…The flexibility, active site volume, solvation, and access path dynamics of six metabolically active mammalian cytochromes P450 (human 2A6, 2C9, 2D6, 2E1, 3A4…”
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Flexibility of human cytochrome P450 enzymes: Molecular dynamics and spectroscopy reveal important function-related variations by Hendrychová, Tereza, Anzenbacherová, Eva, Hudeček, Jiří, Skopalík, Josef, Lange, Reinhard, Hildebrandt, Peter, Otyepka, Michal, Anzenbacher, Pavel

“…To gain more complete insight into flexibility and malleability of five forms of human liver cytochrome P450 enzymes, which play major roles in drug metabolism…”
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Self-Reported Overall Adherence and Correct Inhalation Technique Discordance in Chronic Obstructive Pulmonary Disease Population by Hendrychova, Tereza, Svoboda, Michal, Maly, Josef, Vlcek, Jiri, Zimcikova, Eva, Dvorak, Tomas, Zatloukal, Jaromir, Volakova, Eva, Plutinsky, Marek, Brat, Kristian, Popelkova, Patrice, Kopecky, Michal, Novotna, Barbora, Koblizek, Vladimir

“…Background: Adherence to inhaled medication constitutes a major problem in patients with chronic obstructive pulmonary disease (COPD) globally. However, large…”
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Breathing Out Completely Before Inhalation: The Most Problematic Step in Application Technique in Patients With Non-Mild Chronic Obstructive Pulmonary Disease by Vytrisalova, Magda, Hendrychova, Tereza, Touskova, Tereza, Zimcikova, Eva, Vlcek, Jiri, Nevoranek, Libor, Svoboda, Michal, Hejduk, Karel, Brat, Kristian, Plutinsky, Marek, Novotna, Barbora, Musilova, Pavlina, Cernohorsky, Matej, Koblizek, Vladimir

“…Patient adherence to an inhaled medication application technique (A-ApplT) represents a major health-care issue in patients with chronic obstructive pulmonary…”
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Binding of quinidine radically increases the stability and decreases the flexibility of the cytochrome P450 2D6 active site by Berka, Karel, Anzenbacherová, Eva, Hendrychová, Tereza, Lange, Reinhard, Mašek, Vlastimil, Anzenbacher, Pavel, Otyepka, Michal

“…Human cytochrome P450 2D6 (CYP2D6) is an enzyme of the CYP superfamily responsible for biotransformation of about 20% of drugs of known metabolism containing a…”
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A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding by Child, Emma S., Hendrychová, Tereza, McCague, Karen, Futreal, Andy, Otyepka, Michal, Mann, David J.

“…Cyclin-dependent kinase 2 (cdk2) is a central regulator of the mammalian cell cycle. Here we describe the properties of a mutant form of cdk2 identified during…”
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Adherence to osteoporosis guideline: survey among Czech general practitioners by Vytrisalova, Magda, Fuksa, Leos, Palicka, Vladimir, Byma, Svatopluk, Blazkova, Sarka, Stepan, Jan, Hendrychova, Tereza, Vlcek, Jiri, Pavek, Petr

“…Rationale and objectives General practitioners (GPs) play an important role in management of patients at risk of osteoporosis (OP). The objectives were to…”
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Patterns of Non-adherence to Supplementation with Calcium and Vitamin D in Persistent Postmenopausal Women Are Similar at Start and 1 Year Later: A Qualitative Longitudinal Study by Touskova, Tereza, Vytrisalova, Magda, Palicka, Vladimir, Hendrychova, Tereza, Chen, Yang-Ti, Fuksa, Leos

“…Osteoporosis is a chronic disease and adherence can fluctuate over time. Therefore, longer observation is necessary to investigate the stability of patients'…”
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Prescription of evidence-based medicine drugs by general practitioners to patients after myocardial infarction: outcomes from the Czech Republic by Dosedel, Martin, Hendrychova, Tereza, Maly, Josef, Kubena, Ales, Byma, Svatopluk, Vlcek, Jiri

“…Ischemic heart disease is the most frequent cause of both serious morbidity and mortality of adult population in developed countries. The main aim of the study…”
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Consumption of osteoanabolic drugs and strontium ranelate in the treatment of osteoporosis in the Czech Republic in 2005-2011 by Fuksa, Leos, Vytrisalova, Magda, Hendrychova, Tereza, Hrubesova, Ivana, Vlcek, Jiri, Palicka, Vladimir

“…Anti-osteoporosis drugs with osteoanabolic (teriparatide, intact parathormone) and dual (strontium ranelate) mechanism of action are currently available for…”
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Patterns of non-adherence to supplementation with calcium and vitamin D in persistent postmenopausal women are similar at start and one year later: a qualitative longitudinal study by Tereza Touskova, Magda Vytrisalova, Vladimir Palicka, Tereza Hendrychova, Yang-Ti Chen, Leos Fuksa

“…Background: Osteoporosis is a chronic disease and adherence can fluctuate over time. Therefore, longer observation is necessary to investigate the stability of…”
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Fat- and fiber-related diet behavior among type 2 diabetes patients from distinct regions by Hendrychova, Tereza, Vytrisalova, Magda, Tebbens, Abdullah Alwarafi Jurjen Duintjer, Vankatova, Helena, Leal, Sandra, Kubena, Ales Antonin, Smahelova, Alena, Vlcek, Jiri

“…Purpose: Diet and eating habits are of key importance in patients with type 2 diabetes mellitus (T2DM). The purpose of this comparative study was to analyze…”
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Adherence in adults with type 1 diabetes mellitus correlates with treatment satisfaction but not with adverse events by Hendrychova, Tereza, Vytrisalova, Magda, Smahelova, Alena, Vlcek, Jiri, Kubena, Ales Antonin

“…Diabetes self-care and self-monitoring adherence has a positive effect on the metabolic control of the disease. The aim of this study was to analyze the…”
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Drug holidays: the most frequent type of noncompliance with calcium plus vitamin D supplementation in persistent patients with osteoporosis by Touskova, Tereza, Vytrisalova, Magda, Palicka, Vladimir, Hendrychova, Tereza, Fuksa, Leos, Holcova, Radka, Konopacova, Jana, Kubena, Ales Antonin

“…All current recommendations include calcium and vitamin D (Ca-D) as an integrated part of osteoporosis treatment. The purpose of this pilot study was to…”
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An analysis of fat-related and fiber-related behavior in men and women with type 2 diabetes mellitus: key findings for clinical practice by Hendrychova, Tereza, Vytrisalova, Magda, Vlcek, Jiri, Smahelova, Alena, Kubena, Ales Antonin

“…Despite the efforts of health care providers, adherence of patients with type 2 diabetes to the recommended diet is poor. The aim of this study was to describe…”
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Fat- and fiber-related diet behavior among type 2 diabetes patients from distinct regions by Hendrychova, Tereza, Vytrisalova, Magda, Alwarafi, Abdullah, Duintjer Tebbens, Jurjen, Vankatova, Helena, Leal, Sandra, Kubena, Ales Antonin, Smahelova, Alena, Vlcek, Jiri

“…Diet and eating habits are of key importance in patients with type 2 diabetes mellitus (T2DM). The purpose of this comparative study was to analyze fat- and…”
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