Search Results - "Hendrix, M J"

Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma by Orgaz, J L, Ladhani, O, Hoek, K S, Fernández-Barral, A, Mihic, D, Aguilera, O, Seftor, E A, Bernad, A, Rodríguez-Peralto, J L, Hendrix, M J C, Volpert, O V, Jiménez, B

“…Pigment epithelium-derived factor (PEDF) is a multifunctional secreted glycoprotein that displays broad anti-tumor activity based on dual targeting of the…”
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Vacuolar-type H+-ATPases at the plasma membrane regulate pH and cell migration in microvascular endothelial cells by Rojas, J D, Sennoune, S R, Maiti, D, Bakunts, K, Reuveni, M, Sanka, S C, Martinez, G M, Seftor, E A, Meininger, C J, Wu, G, Wesson, D E, Hendrix, M J C, Martínez-Zaguilán, R

“…Microvascular endothelial cells involved in angiogenesis are exposed to an acidic environment that is not conducive for growth and survival. These cells must…”
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Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior by Hendrix, MJ, Seftor, EA, Seftor, RE, Trevor, KT

“…The expression of intermediate filament proteins is remarkably tissue specific, which suggests that the intermediate filament type(s) present in cells is…”
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Maspin, a Serpin with Tumor-Suppressing Activity in Human Mammary Epithelial Cells by Zou, Zhiqiang, Anisowicz, Anthony, Mary J. C. Hendrix, Thor, Ann, Neveu, Mark, Sheng, Shijie, Rafidi, Kristina, Seftor, Elisabeth, Sager, Ruth

“…A gene encoding a protein related to the serpin family of protease inhibitors was identified as a candidate tumor suppressor gene that may play a role in human…”
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Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility by Chu, YW, Seftor, EA, Romer, LH, Hendrix, MJ

“…Intermediate filaments have been used as cell-type-specific markers in differentiation and pathology; however, recent reports have demonstrated the…”
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Regulation of uveal melanoma interconverted phenotype by hepatocyte growth factor/scatter factor (HGF/SF) by Hendrix, MJ, Seftor, EA, Seftor, RE, Kirschmann, DA, Gardner, LM, Boldt, HC, Meyer, M, Pe'er, J, Folberg, R

“…Human uveal melanoma disseminates initially and preferentially to the liver. This study describes the relationship between the expression of the c-met…”
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Vasculogenic Mimicry and Tumor Angiogenesis by Folberg, Robert, Hendrix, Mary J.C., Maniotis, Andrew J.

“…Tumors require a blood supply for growth and hematogenous dissemination. Much attention has been focused on the role of angiogenesis—the recruitment of new…”
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Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry by Maniotis, Andrew J., Folberg, Robert, Hess, Angela, Seftor, Elisabeth A., Gardner, Lynn M.G., Pe'er, Jacob, Trent, Jeffrey M., Meltzer, Paul S., Hendrix, Mary J.C.

“…Tissue sections from aggressive human intraocular (uveal) and metastatic cutaneous melanomas generally lack evidence of significant necrosis and contain…”
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Expression of Complete Keratin Filaments in Mouse L Cells Augments Cell Migration and Invasion by Chu, Yi-Wen, Runyan, Raymond B., Oshima, Robert G., Mary J. C. Hendrix

“…Intermediate filament proteins have been used to diagnose the origin of specific cells. Classically, vimentin is found in mesenchymal cells, and keratins are…”
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Expression and functional role of CRIPTO-1 in cutaneous melanoma by De Luca, A, Lamura, L, Strizzi, L, Roma, C, D'Antonio, A, Margaryan, N, Pirozzi, G, Hsu, M-Y, Botti, G, Mari, E, Hendrix, M J C, Salomon, D S, Normanno, N

“…Background: CRIPTO-1 (CR-1) is involved in the pathogenesis and progression of human carcinoma of different histological origin. In this study we addressed the…”
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Coexpression of vimentin and keratins by human melanoma tumor cells: correlation with invasive and metastatic potential by Hendrix, M J, Seftor, E A, Chu, Y W, Seftor, R E, Nagle, R B, McDaniel, K M, Leong, S P, Yohem, K H, Leibovitz, A M, Meyskens, Jr, F L

“…Several protein markers, including vimentin, have been used to diagnose human melanoma. Because melanoma often has metastasized by the time of diagnosis, early…”
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Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme by JAMIL, S, CEDERVALL, J, HULTMAN, I, ALI, R, MARGARYAN, N.V, RASMUSON, A, JOHNSEN, J.I, SVEINBJÖRNSSON, B, DALIANIS, T, KANTER, L, ORREGO, A, STRIZZI, L, HENDRIX, M.J.C, SANDSTEDT, B, KOGNER, P, ÄHRLUND-RICHTER, L

“…Embryonic neural tumors are responsible for a disproportionate number of cancer deaths in children. Although dramatic improvements in survival for pediatric…”
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Epigenetic silencing of maspin gene expression in human breast cancers by Domann, Frederick E., Rice, Judd C., Hendrix, Mary J.C., Futscher, Bernard W.

“…Maspin is a tumor suppressor whose expression is lost in many advanced breast cancers. Maspin has been shown to inhibit cell motility, invasion and metastasis;…”
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Maspin Acts at the Cell Membrane to Inhibit Invasion and Motility of Mammary and Prostatic Cancer Cells by Sheng, Shijie, Carey, Juliana, Seftor, Elisabeth A., Dias, Lauren, Mary J. C. Hendrix, Sager, Ruth

“…Maspin, a novel serine protease inhibitor (serpin), inhibits tumor invasion and metastasis of mammary carcinoma. We show here that recombinant maspin protein…”
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Effects of Angiogenesis Inhibitors on Vascular Network Formation by Human Endothelial and Melanoma Cells by van der Schaft, Daisy W. J., Seftor, Richard E. B., Seftor, Elisabeth A., Hess, Angela R., Gruman, Lynn M., Kirschmann, Dawn A., Yokoyama, Yumi, Griffioen, Arjan W., Hendrix, Mary J. C.

“…Endothelial cells involved in vasculogenesis and angiogenesis are key targets in cancer therapy. Recent evidence suggests that tumor cells can express some…”
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Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection by JUN LUO, LUBAROFF, D. M, HENDRIX, M. J. C

“…Our previous studies have demonstrated the heterogeneous expression of E-cadherin in a Dunning rat prostate tumor model. From this model, cloned…”
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maspin Suppresses the invasive phenotype of human breast carcinoma by SEFTOR, R. E. B, SEFTOR, E. A, SHIJIE SHENG, PEMBERTON, P. A, SAGER, R, HENDRIX, M. J. C

“…The recently discovered tumor suppressor gene maspin has been shown to inhibit tumor cell motility, invasion, and metastasis in breast cancer by our…”
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Association between Keratin and Vimentin Expression, Malignant Phenotype, and Survival in Postmenopausal Breast Cancer Patients by THOMAS, P. A, KIRSCHMANN, D. A, CERHAN, J. R, FOLBERG, R, SEFTOR, E. A, SELLERS, T. A, HENDRIX, M. J. C

“…Pathology observational reports and experimental data suggest that keratin and vimentin intermediate filament (IF) coexpression in breast cancer confers a more…”
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Role of the alpha v beta 3 integrin in human melanoma cell invasion by Seftor, R E, Seftor, E A, Gehlsen, K R, Stetler-Stevenson, W G, Brown, P D, Ruoslahti, E, Hendrix, M J

“…The human melanoma cell line A375M expresses the vitronectin receptor (alpha v beta 3 integrin) on its cell surface. Treatment of A375M cells with either…”
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Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line by Chu, YW, Yang, PC, Yang, SC, Shyu, YC, Hendrix, MJ, Wu, R, Wu, CW

“…To better understand the mechanism(s) underlying lung cancer invasion and metastasis, a Transwell invasion chamber was used to select progressively more…”
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