Search Results - "Hendriks, Linda J. A."

Controlled Encapsulation of Multiple Proteins in Virus Capsids by Minten, Inge J, Hendriks, Linda J. A, Nolte, Roeland J. M, Cornelissen, Jeroen J. L. M

“…Multiple proteins can be bound within the Cowpea Chlorotic Mottle Virus capsid shell in an efficient and controlled manner by using heterodimeric coiled-coil…”
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Qualitative and Semiquantitative Analysis of Composite Mixtures of Antibodies by Native Mass Spectrometry by Rosati, Sara, Thompson, Natalie J, Barendregt, Arjan, Hendriks, Linda J. A, Bakker, Alexander B. H, de Kruif, John, Throsby, Mark, van Duijn, Esther, Heck, Albert J. R

“…Native mass spectrometry was evaluated for the qualitative and semiquantitative analysis of composite mixtures of antibodies representing biopharmaceutical…”
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Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells by Dommerholt, Jan, Schmidt, Samuel, Temming, Rinske, Hendriks, Linda J.A, Rutjes, Floris P.J.T, van Hest, Jan C.M, Lefeber, Dirk J, Friedl, Peter, van Delft, Floris L

“…I can see clearly now: Bicyclo[6.1.0]non‐4‐yne, an easily prepared, symmetrical cycloalkyne, displays excellent reaction kinetics in strain‐promoted…”
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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade by Geuijen, Cecile, Tacken, Paul, Wang, Liang-Chuan, Klooster, Rinse, van Loo, Pieter Fokko, Zhou, Jing, Mondal, Arpita, Liu, Yao-bin, Kramer, Arjen, Condamine, Thomas, Volgina, Alla, Hendriks, Linda J. A., van der Maaden, Hans, Rovers, Eric, Engels, Steef, Fransen, Floris, den Blanken-Smit, Renate, Zondag-van der Zande, Vanessa, Basmeleh, Abdul, Bartelink, Willem, Kulkarni, Ashwini, Marissen, Wilfred, Huang, Cheng-Yen, Hall, Leslie, Harvey, Shane, Kim, Soyeon, Martinez, Marina, O’Brien, Shaun, Moon, Edmund, Albelda, Steven, Kanellopoulou, Chrysi, Stewart, Shaun, Nastri, Horacio, Bakker, Alexander B. H., Scherle, Peggy, Logtenberg, Ton, Hollis, Gregory, de Kruif, John, Huber, Reid, Mayes, Patrick A., Throsby, Mark

“…Immune checkpoint inhibitors demonstrate clinical activity in many tumor types, however, only a fraction of patients benefit. Combining CD137 agonists with…”
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Complex mixtures of antibodies generated from a single production qualitatively and quantitatively evaluated by native Orbitrap mass spectrometry by Thompson, Natalie J, Hendriks, Linda JA, de Kruif, John, Throsby, Mark, Heck, Albert JR

“…Composite antibody mixtures designed to combat diseases present a new, rapidly emerging technology in the field of biopharmaceuticals. The combination of…”
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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade by Geuijen, Cecile A.W., De Nardis, Camilla, Maussang, David, Rovers, Eric, Gallenne, Tristan, Hendriks, Linda J.A., Visser, Therese, Nijhuis, Roy, Logtenberg, Ton, de Kruif, John, Gros, Piet, Throsby, Mark

“…HER2-driven cancers require phosphatidylinositide-3 kinase (PI3K)/Akt signaling through HER3 to promote tumor growth and survival. The therapeutic benefit of…”
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A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1 by De Nardis, Camilla, Hendriks, Linda J.A., Poirier, Emilie, Arvinte, Tudor, Gros, Piet, Bakker, Alexander B.H., de Kruif, John

“…Bispecific antibodies combine two different antigen-binding sites in a single molecule, enabling more specific targeting, novel mechanisms of action, and…”
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MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis by van Loo, Pieter Fokko, Hangalapura, Basav N, Thordardottir, Soley, Gibbins, John D, Veninga, Henrike, Hendriks, Linda J A, Kramer, Arjen, Roovers, Rob C, Leenders, Marij, de Kruif, John, Doornbos, Robert P, Sirulnik, Andres, Throsby, Mark, Logtenberg, Ton, Dolstra, Harry, Bakker, Alexander B H

“…: We report the characterization of MCLA-117, a novel T cell-redirecting antibody for acute myeloid leukaemia (AML) treatment targeting CD3 on T cells and…”
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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade by Geuijen, Cecile A.W., De Nardis, Camilla, Maussang, David, Rovers, Eric, Gallenne, Tristan, Hendriks, Linda J.A., Visser, Therese, Nijhuis, Roy, Logtenberg, Ton, de Kruif, John, Gros, Piet, Throsby, Mark

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Metal-Ion-Induced Formation and Stabilization of Protein Cages Based on the Cowpea Chlorotic Mottle Virus by Minten, Inge J., Wilke, Koos D. M., Hendriks, Linda J. A., van Hest, Jan C. M., Nolte, Roeland J. M., Cornelissen, Jeroen J. L. M.

“…The cowpea chlorotic mottle virus (CCMV) is a versatile building block for the construction of nanoreactors and functional materials. Upon RNA removal, the…”
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Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three‐Dimensional Imaging of Living Cells by Dommerholt, Jan, Schmidt, Samuel, Temming, Rinske, Hendriks, Linda J. A., Rutjes, Floris P. J. T., van Hest, Jan C. M., Lefeber, Dirk J., Friedl, Peter, van Delft, Floris L.

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A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G 1 by De Nardis, Camilla, Hendriks, Linda J A, Poirier, Emilie, Arvinte, Tudor, Gros, Piet, Bakker, Alexander B H, de Kruif, John

“…Bispecific antibodies combine two different antigen-binding sites in a single molecule, enabling more specific targeting, novel mechanisms of action, and…”
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Abstract 2936: INCA33890, a novel PD-1×TGFꞵR2 bispecific antibody conditionally antagonizes TGFꞵ signaling in primary immune cells co-expressing PD-1 by Wang, Liang-Chuan S., Klooster, Rinse, Kulkarni, Ashwini, de Vinuesa, Amaya Garcia, Soloviev, Maxim, Hendriks, Linda JA, Huo, Lu, Weber, Michael, Mondal, Arpita, Zhao, Yonghong, Harvey, Shane, He, Xin, Chang, Hong, Horsey, April, Volgina, Alla, Zhang, Yue, Pandey, Veethika, Yang, Yan-Ou, Rios-Doria, Jonathan, Eruslanov, Evgeniy, Powell, Daniel J., Albelda, Steven M., de Kruif, John, Nastri, Horacio, Geuijen, Cecile, Mayes, Patrick A.

“…Transforming growth factor-β (TGFβ) signaling is common in many solid tumors and is initiated by binding of the high affinity canonical ligands TGFβ1, 2, οr 3…”
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Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells by Dommerholt, Jan, Schmidt, Samuel, Temming, Rinske, Hendriks, Linda J. A., Rutjes, Floris P. J. T., van Hest, Jan C. M., Lefeber, Dirk J., Friedl, Peter, van Delft, Floris L.

“…Spannungslösend: Das leicht herstellbare, symmetrische Cycloalkin Bicyclo[6.1.0]non‐4‐in zeigt hervorragende Reaktionskinetiken bei spannungsgetriebenen…”
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