Search Results - "Hendrickx, AG"

Vitamin A teratogenicity and risk assessment in the macaque retinoid model by Hendrickx, A.G, Peterson, P, Hartmann, D, Hummler, H

“…Studies were performed in the cynomolgus monkey ( Macaca fascicularis) to provide risk assessment information on safe dose levels of Vitamin A during human…”
Get full text

Modulation of behavioral performance of prepubertal monkeys by moderate dietary zinc deprivation by Golub, MS, Takeuchi, PT, Keen, CL, Gershwin, ME, Hendrickx, AG, Lonnerdal, B

“…Young rhesus monkeys (Macaca mulatta, n = 14) 25–30 mo of age were fed a zinc-deficient (ZD) diet (2 µg Zn/g diet) (moderate zinc deprivation) over 15 week…”
Get full text

Nonhuman primates and teratological research by Hendrickx, A G, Binkerd, P E

“…Nonhuman primates were first recognized as models for the study of developmental toxicity (teratology) following the thalidomide tragedy. Since that time they…”
Get more information

Developmental zinc deficiency and behavior by Golub, M S, Keen, C L, Gershwin, M E, Hendrickx, A G

“…The majority of studies of developmental zinc deficiency and behavior were conducted in laboratory animals, primarily rats and rhesus monkeys. Effects on food…”
Get more information

Effect of phytate removal on zinc absorption from soy formula by Lönnerdal, B, Bell, J, Hendrickx, AG, Burns, RA, Keen, CL

“…Low zinc bioavailability from soy formula may be the result of the formula’s phytate content. We assessed the effect of phytate removal from soy formula on Zn…”
Get full text

13‐cis‐retinoic acid alters neural crest cells expressing Krox‐20 and Pax‐2 in macaque embryos by Makori, Norbert, Peterson, Pamela E., Wei, Xin, Hummler, Hans, Hendrickx, Andrew G.

“…This study investigates hindbrain and associated neural crest (NCC), otocyst, and pharyngeal arch development in monkey embryos following teratogenic exposure…”
Get full text

Titration of an SIVmac251 stock by vaginal inoculation of Indian and Chinese origin rhesus macaques: transmission efficiency, viral loads, and antibody responses by Marthas, M L, Lu, D, Penedo, M C, Hendrickx, A G, Miller, C J

“…The purpose of this study was to determine whether rhesus monkeys of Chinese origin are suitable for studies of mucosal lentivirus transmission by comparing…”
Get more information

Serum leptin in nonpregnant and pregnant women and in old and new world nonhuman primates by Castracane, V Daniel, Hendrickx, Andrew G, Henson, Michael C

“…Leptin is a hormone that is produced during mammalian pregnancy in the placental trophoblast and other tissues, including! fetal and maternal adipocytes…”
Get more information

Teratogenicity of all-trans retinoic acid during early embryonic development in the cynomolgus monkey (Macaca fascicularis) by Hendrickx, A G, Hummler, H

“…The embryotoxic and teratogenic potential of all-trans retinoic acid was assessed following exposure prior to and during early organogenesis in the cynomolgus…”
Get more information

Maternal toxicokinetics, metabolism, and embryo exposure following a teratogenic dosing regimen with 13-cis-retinoic acid (isotretinoin) in the cynomolgus monkey by Hummler, H, Hendrickx, A G, Nau, H

“…The maternal pharmacokinetics, metabolism, and placental transfer of 13-cis-retinoic acid (isotretinoin) have been determined in the cynomolgus monkey using a…”
Get more information

Intravaginal inoculation of rhesus macaques with cell-free simian immunodeficiency virus results in persistent or transient viremia by Miller, C J, Marthas, M, Torten, J, Alexander, N J, Moore, J P, Doncel, G F, Hendrickx, A G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The nonhuman primate as a model of developmental immunotoxicity by Hendrickx, A G, Makori, N, Peterson, P

“…Macaques are well suited for preclinical testing of biopharmaceutics due to reproductive and developmental similarities with humans. In order to characterize…”
Get more information

Neuropathogenesis Induced by Rhesus Cytomegalovirus in Fetal Rhesus Monkeys (Macaca mulatta) by Tarantal, Alice F., Salamat, M. Shahriar, Britt, William J., Luciw, Paul A., Hendrickx, Andrew G., Barry, Peter A.

“…Rhesus cytomegalovirus (RhCMV) infection of rhesus macaques offers opportunities to analyze mechanisms of CMV pathogenesis in a primate species. Four fetal…”
Get full text

Periconceptional vitamin a use: How much is teratogenic? by Miller, Richard K, Hendrickx, Andrew G, Mills, James L, Hummler, Hans, Wiegand, Ulf-w

“…The objective of the review is to determine whether preformed vitamin A (retinol and retinyl esters) is teratogenic at dosages commonly used by women living in…”
Get full text

Functional and morphological development of lymphoid tissues and immune regulatory and effector function in rhesus monkeys: cytokine-secreting cells, immunoglobulin-secreting cells, and CD5(+) B-1 cells appear early in fetal development by Makori, Norbert, Tarantal, Alice F, Lü, Fabien X, Rourke, Tracy, Marthas, Marta L, McChesney, Michael B, Hendrickx, Andrew G, Miller, Christopher J

“…Little is known regarding the timing of immune ontogeny and effector function in fetal humans and nonhuman primates. We studied the organization of lymphocyte…”
Get full text

Importance of early exposure to 13-cis retinoic acid to induce teratogenicity in the cynomolgus monkey by Korte, R, Hummler, H, Hendrickx, A G

“…The teratogenic potential of 13-cis retinoic acid (13-cis RA) was further assessed in cynomolgus macaques (Macaca fascicularis) following exposure to two…”
Get more information

From blastocyst to placenta: the morphology of implantation in the baboon by Enders, A C, Lantz, K C, Peterson, P E, Hendrickx, A G

“…Implantation and placentation in the baboon share many morphological features with other primates, as well as having some specific distinctions. The ability to…”
Get full text

The sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (Macaca fascicularis) by Hendrickx, A G

Get more information

Intracellular pH monkey embryos at various stages of organogenesis estimated by dimethadione distribution by Collins, M D, Scott, Jr, W J, Hendrickx, A G, Peterson, P E, Nau, H

“…Previous experiments using the transplacental distribution of 14C-DMO (5,5-dimethyloxazolidine-2,4-dione or commonly known as dimethadione) have demonstrated…”
Get more information

Effect of single-dose, early luteal phase administration of mifepristone (RU486) on implantation stage endometrium in the rhesus monkey by GHOSH, D, SENGUPTA, J, HENDRICKX, A. G

“…The characteristics of implantation stage endometrium following a single-dose, early luteal phase application of mifepristone (RU486) in proven conception…”
Get full text