Search Results - "Henck, J W"

Pre- and Postnatal Toxicity of the HMG-CoA Reductase Inhibitor Atorvastatin in Rats by Henck, J. W., Craft, W. R., Black, A., Colgin, J., Anderson, J. A.

“…Atorvastatin is a potent inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which catalyzes the conversion of HMG-CoA to…”
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Growth and development in rats given recombinant human epidermal growth Factor1-48 as neonates by HENCK, J. W, REINDEL, J. F, ANDERSON, J. A

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Validation of automated behavioral test systems by Henck, Judith W, Frahm, Denise Traxler, Anderson, John A

“…A positive control study was conducted as part of the ongoing validation program for developmental neurotoxicity testing in our laboratory using a standard…”
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Female reproductive and developmental toxicology: overview and current approaches by Kamrin, M A, Carney, E W, Chou, K, Cummings, A, Dostal, L A, Harris, C, Henck, J W, Loch-Caruso, R, Miller, R K

“…In recent years, concern about possible female reproductive and developmental toxicity due to environmental contaminants, such as PCBs, has been growing…”
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Developmental neurotoxicity of CI-943: A novel antipsychotic by Henck, Judith W., Petrere, Judith A., Anderson, John A.

“…Offspring from Sprague-Dawley rats administered 0, 10, 25, or 75 mg/kg/day CI-943 in the diet prior to mating and throughout gestation and lactation (fertility…”
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Developmental neurotoxicity of polybrominated biphenyls by Henck, J W, Mattsson, J L, Rezabek, D H, Carlson, C L, Rech, R H

“…Female F0 generation Sprague-Dawley rats received daily oral doses of 0, 0.2, or 2 mg/kg polybrominated biphenyls (PBB) as fireMaster BP-6 from Day 6 of…”
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Growth and development in rats given recombinant human epidermal growth factor(1-48) as neonates by Henck, J W, Reindel, J F, Anderson, J A

“…To assess effects of supraphysiologic doses of human recombinant epidermal growth factor(1-48) (rhEGF(1-48)) on neonatal rats, 10 litters of Wistar…”
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Effect of perinatal polybrominated biphenyl exposure on acquisition and performance of an autoshaping paradigm by Henck, J W, Rech, R H

“…Pregnant Sprague-Dawley rats received oral doses of 0, 0.2 or 2 mg/kg/day polybrominated biphenyls (PBB) as fireMaster BP-6 (BP-6) from day 6 of gestation…”
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Comparison of anorexia and motor disruption by cyclazocine and quipazine by Henck, J W, Rezabek, D H, Rech, R H

“…The mixed narcotic agonist-antagonist cyclazocine and the 5-HT agonist quipazine disrupt food-rewarded fixed ratio-40 (FR-40) operant behavior in rats as a…”
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Naloxone alters the effects of LSD, DOM and quipazine on operant behavior of rats by Mokler, D J, Commissaris, R L, Henck, J W, Rech, R H

“…Administration of the indolealkylamine hallucinogen d-lysergic acid diethylamide (LSD), the phenethylamine hallucinogen 2,5-dimethoxy-4-methylamphetamine (DOM)…”
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NEUROTOXICITY OF MISONIDAZOLE IN RATS FOLLOWING INTRAVENOUS ADMINISTRATION by GRAZIANO, MICHAEL J., HENCK, JUDITH W., MEIERHENRY, EARL F., GOUGH, ALEX W.

“…Misonidazole is a hypoxic cell radiosensitizer that induces a peripheral neuropathy in humans after exceeding a schedule-dependent cumulative threshold dose…”
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Growth and Development in Rats Given Recombinant Human Epidermal Growth Factor sub(1-48) as Neonates by Henck, J W, Reindel, J F, Anderson, JA

“…To assess effects of supraphysiologic doses of human recombinant epidermal growth factor sub(1-48) (rhEGF sub(1-48)) on neonatal rats, 10 litters of Wistar…”
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Subchronic dermal toxicity study of trichlorobenzene in the rabbit by Rao, K S, Johnson, K A, Henck, J W

“…Groups of five male and five female New Zealand albino rabbits were treated by skin application with either 0 (distilled water control), 30, 150 or 450 mg/kg…”
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Reproductive toxicity testing of therapeutic biotechnology agents by Henck, Judith W., Hilbish, Kim G., Serabian, Mercedes A., Cavagnaro, Joy A., Hendrickx, Andrew G., Agnish, Narsingh D., Kung, Ada H. C., Mordenti, Joyce

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Cyclazocine disruption of operant behavior is antagonized by naloxone and metergoline by Henck, J W, Mokler, D J, Commissaris, R L, Rech, R H

“…Male Sprague-Dawley rats were trained to press a lever on a fixed ratio-40 (FR-40) schedule for food reinforcement. Doses ranging from 0.5 to 16 mg/kg of the…”
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Behavioral interactions of opioid agonists and antagonists with serotonergic systems by Rech, R H, Mokler, D J, Commissaris, R L, Henck, J W

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A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation by Geiser, Andrew G, Hummel, Conrad W, Draper, Michael W, Henck, Judith W, Cohen, Ilene R, Rudmann, Daniel G, Donnelly, Kevin B, Adrian, Mary D, Shepherd, Timothy A, Wallace, Owen B, McCann, Denis J, Oldham, Samuel W, Bryant, Henry U, Sato, Masahiko, Dodge, Jeffrey A

“…The use of selective estrogen receptor modulators for the treatment of estrogen-dependent diseases in premenopausal women has been hindered by undesirable…”
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Hazard Identification and Predictability of Children's Health Risk from Animal Data by Morford, LaRonda L., Henck, Judith W., Breslin, William J., DeSesso, John M.

“…Children differ from adults both physiologically and behaviorally. These differences can affect how and when exposures to xenobiotics occur and the resulting…”
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Skin sensitization potential of trisodium ethylenediaminetetraacetate by Henck, J W, Lockwood, D D, Olson, K J

“…A sodium salt of ethylenediaminetetraacetate (Na3EDTA) and ethylenediamine (EDA) were subjected to a repeated insult patch test on Hartley albino guinea pigs…”
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Embryotoxicity of inhaled sulfur dioxide and carbon monoxide in mice and rabbits by Murray, F J, Schwetz, B A, Crawford, A A, Henck, J W, Quast, J F, Staples, R E

“…The embryotoxic and teratogenic potential of sulfur dioxide (SO2) was evaluated in CF-1 and New Zealand rabbits exposed to SO2 alone or in combination with…”
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