Search Results - "Henar Alonso, M"
-
1
Lymphocytic infiltration in stage II microsatellite stable colorectal tumors: A retrospective prognosis biomarker analysis
Published in PLoS medicine (01-09-2020)“…Recognized clinical risk factors for progression (emergency presentation, poorly differentiated tumor, depth of tumor invasion, and adjacent organ involvement)…”
Get full text
Journal Article -
2
Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component
Published in British journal of cancer (25-07-2017)“…Background: Somatic copy number aberrations (CNAs) are common acquired changes in cancer cells having an important role in the progression of colon cancer…”
Get full text
Journal Article -
3
NTHL1 biallelic mutations seldom cause colorectal cancer, serrated polyposis or a multi-tumor phenotype, in absence of colorectal adenomas
Published in Scientific reports (21-06-2019)“…The cancer-predisposing syndrome caused by biallelic mutations in NTHL1 may not be a solely colorectal cancer (CRC) and polyposis syndrome but rather a…”
Get full text
Journal Article -
4
Colon-specific eQTL analysis to inform on functional SNPs
Published in British journal of cancer (16-10-2018)“…Background Genome-wide association studies on colorectal cancer have identified more than 60 susceptibility loci, but for most of them there is no clear…”
Get full text
Journal Article -
5
DNA methylation events in transcription factors and gene expression changes in colon cancer
Published in Epigenomics (01-09-2020)“…Gain insight about the role of DNA methylation in the malignant growth of colon cancer. Methylation and gene expression from 90 adjacent-tumor paired tissues…”
Get full text
Journal Article -
6
Lung metastases share common immune features regardless of primary tumor origin
Published in Journal for immunotherapy of cancer (01-06-2020)“…BackgroundOnly certain disseminated cells are able to grow in secondary organs to create a metastatic tumor. Under the hypothesis that the immune…”
Get full text
Journal Article -
7
Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study
Published in Scientific reports (24-02-2017)“…Colorectal cancer (CRC) screening of the average risk population is only indicated according to age. We aim to elaborate a model to stratify the risk of CRC by…”
Get full text
Journal Article -
8
Colorectal cancer, sun exposure and dietary vitamin D and calcium intake in the MCC-Spain study
Published in Environment international (01-12-2018)“…To explore the association of colorectal cancer with environmental solar radiation and sun exposure behavior, considering phenotypic variables (eye color, hair…”
Get full text
Journal Article -
9
Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer
Published in Clinical cancer research (15-10-2015)“…Somatic mutations occur at early stages of adenoma and accumulate throughout colorectal cancer progression. The aim of this study was to characterize the…”
Get full text
Journal Article -
10
The Use of Antihypertensive Medication and the Risk of Breast Cancer in a Case-Control Study in a Spanish Population: The MCC-Spain Study
Published in PloS one (10-08-2016)“…The evidence on the relationship between breast cancer and different types of antihypertensive drugs taken for at least 5 years is limited and inconsistent…”
Get full text
Journal Article -
11
Dietary inflammatory index and inflammatory gene interactions in relation to colorectal cancer risk in the Bellvitge colorectal cancer case-control study
Published in Genes & nutrition (01-01-2015)“…Chronic inflammation is an important factor in colorectal carcinogenesis. However, evidence on the effect of pro-inflammatory and anti-inflammatory foods and…”
Get full text
Journal Article -
12
Tumour characteristics and survivorship in a cohort of breast cancer: the MCC-Spain study
Published in Breast cancer research and treatment (01-06-2020)“…Purpose The objective of this study is to analyse the relative survival with breast cancer in women diagnosed after new treatments were generalised and to…”
Get full text
Journal Article -
13
Adoptive NK Cell Transfer as a Treatment in Colorectal Cancer Patients: Analyses of Tumour Cell Determinants Correlating With Efficacy In Vitro and In Vivo
Published in Frontiers in immunology (07-06-2022)“…Background Colorectal cancer (CRC) is a heterogeneous disease with variable mutational profile and tumour microenvironment composition that influence tumour…”
Get full text
Journal Article -
14
Dietary flavonoids, lignans and colorectal cancer prognosis
Published in Scientific reports (15-09-2015)“…Flavonoids and lignans are polyphenol classes with anticarcinogenic activities against colorectal cancer (CRC). However, very limited epidemiological evidence…”
Get full text
Journal Article -
15
Use of non-steroidal anti-inflammatory drugs and risk of breast cancer: The Spanish Multi-Case-control (MCC) study
Published in BMC cancer (20-08-2016)“…The relationship between non-steroidal anti-inflammatory drug (NSAID) consumption and breast cancer has been repeatedly studied, although the results remain…”
Get full text
Journal Article -
16
Tumor immune infiltration estimated from gene expression profiles predicts colorectal cancer relapse
Published in Oncoimmunology (01-01-2021)“…A substantial fraction of patients with stage I-III colorectal adenocarcinoma (CRC) experience disease relapse after surgery with curative intent. However,…”
Get full text
Journal Article -
17
Changes of CD68, CD163, and PD-L1 tumor expression during high-dose-rate and pulsed-dose-rate brachytherapy for cervical cancer
Published in Brachytherapy (01-01-2020)“…We hypothesized that radiation doses delivered with high-dose-rate (HDR) and pulsed-dose-rate (PDR) brachytherapy in patients with cervical cancer could…”
Get full text
Journal Article -
18
Mutanome and expression of immune response genes in microsatellite stable colon cancer
Published in Oncotarget (05-04-2016)“…The aim of this study was to analyze the impact of the mutanome in the prognosis of microsatellite stable stage II CRC tumors. The exome of 42 stage II,…”
Get full text
Journal Article -
19
Telomere length alterations in microsatellite stable colorectal cancer and association with the immune response
Published in Biochimica et biophysica acta. Molecular basis of disease (01-09-2018)“…Telomeres are repetitive sequences (TTAGGG) located at the end of chromosomes. Telomeres progressively shorten with each cell replication cycle, ultimately…”
Get full text
Journal Article -
20
Genetically determined telomere length and multiple myeloma risk and outcome
Published in Blood cancer journal (New York) (14-04-2021)“…Telomeres are involved in processes like cellular growth, chromosomal stability, and proper segregation to daughter cells. Telomere length measured in…”
Get full text
Journal Article