Long-term plasmapheresis therapy in the management of focal segmental glomerulosclerosis recurrence after kidney transplantation

The recurrence of primary focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) appears in 30 % of the recipients. Sometimes it can cause the loss of the allograft. Although many treatments for this condition have been reported, 20 %–40 % of the affected patients are refractory...

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Bibliographic Details
Published in:	Transfusion and apheresis science Vol. 60; no. 2; p. 103046
Main Authors:	Ramirez-Guerrero, Gonzalo, Sevillano Prieto, Angel M, Jara-Vilugrón, Fernando, Polanco Fernandez, Natalia, Gonzalez Monte, Esther, Henandez Vicente, Ana, Rodriguez Gayo, Lucia C, Praga Terente, Manuel, Andrés Belmonte, Amado
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-04-2021
Subjects:	Focal segmental glomerulosclerosis Health technology assessment Kidney transplantation Plasmapheresis Focal segmental glomerulosclerosis Kidney transplantation Plasmapheresis
Online Access:	Get full text
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Summary:	The recurrence of primary focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) appears in 30 % of the recipients. Sometimes it can cause the loss of the allograft. Although many treatments for this condition have been reported, 20 %–40 % of the affected patients are refractory or presents frequents relapses. In this paper we describe the evolution of three recipients treated with long-term plasmapheresis therapy after a recurrence of FSGS with a bad or incomplete response to other treatments. Although our findings require confirmation, long-term plasmapheresis could be a therapeutic option for this condition.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1473-0502 1878-1683
DOI:	10.1016/j.transci.2020.103046