Search Results - "Hems, Edward S"

CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins by Hems, Edward S, Wagstaff, Ben A, Saalbach, Gerhard, Field, Robert A

“…In the context of discovering and quantifying terminal alkyne-based natural products, here we report the combination of CuAAC click chemistry with LC-MS for…”
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Discovery and characterisation of an amidine-containing ribosomally-synthesised peptide that is widely distributed in nature by Russell, Alicia H, Vior, Natalia M, Hems, Edward S, Lacret, Rodney, Truman, Andrew W

“…Ribosomally synthesised and post-translationally modified peptides (RiPPs) are a structurally diverse class of natural product with a wide range of…”
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Assessing the Toxicity and Mitigating the Impact of Harmful Prymnesium Blooms in Eutrophic Waters of the Norfolk Broads by Wagstaff, Ben A, Pratscher, Jennifer, Rivera, Peter Paolo L, Hems, Edward S, Brooks, Elliot, Rejzek, Martin, Todd, Jonathan D, Murrell, J. Colin, Field, Robert A

“…Prymnesium parvum is a toxin-producing microalga, which causes harmful algal blooms globally, frequently leading to massive fish kills that have adverse…”
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Heterologous Expression of the Formicamycin Biosynthetic Gene Cluster Unveils Glycosylated Fasamycin Congeners by McDonald, Hannah P., Alford, Abigail, Devine, Rebecca, Hems, Edward S., Nepogodiev, Sergey A., Arnold, Corinne J., Rejzek, Martin, Stanley-Smith, Anna, Holmes, Neil A., Hutchings, Matthew I., Wilkinson, Barrie

“…Formicamycins and their biosynthetic intermediates the fasamycins are polyketide antibiotics produced by Streptomyces formicae KY5 from a pathway encoded by…”
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Synthesis of glyceryl glycosides related to A-type prymnesin toxins by Hems, Edward S., Nepogodiev, Sergey A., Rejzek, Martin, Field, Robert A.

“…A suite of glycosylated glycerol derivatives representing various fragments of the glycosylated ichthyotoxins called prymnesins were chemically synthesised…”
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Profiling of Sugar Nucleotides by Rejzek, Martin, Hill, Lionel, Hems, Edward S, Kuhaudomlarp, Sakonwan, Wagstaff, Ben A, Field, Robert A

“…Sugar nucleotides are essential building blocks for the glycobiology of all living organisms. Detailed information on the types of sugar nucleotides present in…”
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Corrigendum to “Synthesis of glyceryl glycosides related to A-type prymnesin toxins” Carbohydr. Res. 463 (2018) 14-23 by Hems, Edward S., Nepogodiev, Sergey A., Rejzek, Martin, Field, Robert A.

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Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses by Wagstaff, Ben A, Hems, Edward S, Rejzek, Martin, Pratscher, Jennifer, Brooks, Elliot, Kuhaudomlarp, Sakonwan, O'Neill, Ellis C, Donaldson, Matthew I, Lane, Steven, Currie, John, Hindes, Andrew M, Malin, Gill, Murrell, J Colin, Field, Robert A

“…is a toxin-producing microalga that causes harmful algal blooms globally, which often result in large-scale fish kills that have severe ecological and economic…”
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The catechol moiety of obafluorin is essential for antibacterial activity by Batey, Sibyl F. D, Davie, Melissa J, Hems, Edward S, Liston, Jonathon D, Scott, Thomas A, Alt, Silke, Francklyn, Christopher S, Wilkinson, Barrie

“…Obafluorin is a Pseudomonas fluorescens antibacterial natural product that inhibits threonyl-tRNA synthetase (ThrRS). It acts as a broad-spectrum antibiotic…”
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Decolourising isinglass derived from aqua-farmed sturgeon by sonication by Hems, Edward S., Curtis, Antoinette E.

“…Isinglass derived from the swim bladder of wild-caught sturgeon has been used extensively in conservation as an adhesive and consolidant. It is favoured for…”
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