Search Results - "Hemraz, Usha"

Recent advances in cellulose nanocrystals-based antimicrobial agents by Hemraz, Usha D., Lam, Edmond, Sunasee, Rajesh

“…Over the past five years, there has been growing interest in the design of modified cellulose nanocrystals (CNCs) as nanoscale antimicrobial agents in…”
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Cellulose nanocrystals: a versatile nanoplatform for emerging biomedical applications by Sunasee, Rajesh, Hemraz, Usha D, Ckless, Karina

“…Cellulose nanocrystals (CNCs) are bio-based nanomaterials typically derived from the acid hydrolysis of the most abundant natural polymer, cellulose. These…”
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The Effects of High Pressure and High Temperature in Semidilute Aqueous Cellulose Nanocrystal Suspensions by Saha, Sudeshna, Hemraz, Usha D, Boluk, Yaman

“…A semidilute cellulose nanocrystal suspension was tested for pressure, volume, temperature dependencies of its viscosity and density. The compression of a 2.0…”
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Structure of poly(N-isopropylacrylamide) brushes and steric stability of their grafted cellulose nanocrystal dispersions by Hemraz, Usha D., Lu, Ang, Sunasee, Rajesh, Boluk, Yaman

“…[Display omitted] •NIPAAm brushes were successfully polymerized on CNC nanoparticles.•Thickness of brushes was proportional to 1/3 power of grafting…”
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Preparation and Surface Functionalization of Carboxylated Cellulose Nanocrystals by Lam, Edmond, Hemraz, Usha D

“…In recent years, cellulose nanocrystals (CNCs) have emerged as a leading biomass-based nanomaterial owing to their unique functional properties and sustainable…”
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Synthetic Strategies for the Fabrication of Cationic Surface-Modified Cellulose Nanocrystals by Sunasee, Rajesh, Hemraz, Usha

“…Cellulose nanocrystals (CNCs) are renewable nanosized materials with exceptional physicochemical properties that continue to garner a high level of attention…”
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Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant by Akache, Bassel, Renner, Tyler M., Tran, Anh, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Duque, Diana, Haukenfrers, Julie, Rossotti, Martin A., Gaudreault, Francis, Hemraz, Usha D., Lam, Edmond, Régnier, Sophie, Chen, Wangxue, Gervais, Christian, Stuible, Matthew, Krishnan, Lakshmi, Durocher, Yves, McCluskie, Michael J.

“…The huge worldwide demand for vaccines targeting SARS-CoV-2 has necessitated the continued development of novel improved formulations capable of reducing the…”
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Design of chitosan nanocrystals decorated with amino acids and peptides by Hrapovic, Sabahudin, Martinez-Farina, Camilo F., Sui, Jessie, Lavertu, Jean-Danick, Hemraz, Usha D.

“…Antimicrobial peptides (AMPs) offer a great promise in designing new therapeutics due to their ability to interfere in bacterial growth by penetrating the cell…”
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Fabrication of thermo-responsive multicore microcapsules using a facile extrusion process by Lavertu, Jean-Danick, Bawa, Kamaljeet Kaur, Hrapovic, Sabahudin, Fu, Dong, Oh, Jung Kwon, Hemraz, Usha D

“…A process employing extrusion was used to produce multicore microcapsules composed of multiple beads. The inner beads were made from -carrageenan (-c), a…”
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Cationic Poly(2-aminoethylmethacrylate) and Poly(N‑(2-aminoethylmethacrylamide) Modified Cellulose Nanocrystals: Synthesis, Characterization, and Cytotoxicity by Hemraz, Usha D, Campbell, Kendra A, Burdick, James S, Ckless, Karina, Boluk, Yaman, Sunasee, Rajesh

“…Cellulose nanocrystals (CNCs) continue to gain increasing attention in the materials community as sustainable nanoparticles with unique chemical and mechanical…”
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Mechanisms of the immune response cause by cationic and anionic surface functionalized cellulose nanocrystals using cell-based assays by Despres, Hannah W., Sabra, Adham, Anderson, Phil, Hemraz, Usha D., Boluk, Yaman, Sunasee, Rajesh, Ckless, Karina

“…The interest in functionalized cellulose nanocrystals (CNCs) for multiple biomedical application has been increasing in recent years. CNCs are suitable to…”
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Intranasal administration of unadjuvanted SARS‐CoV‐2 spike antigen boosts antigen‐specific immune responses induced by parenteral protein subunit vaccine prime in mice and hamsters by Agbayani, Gerard, Akache, Bassel, Renner, Tyler M., Tran, Anh, Stuible, Matthew, Dudani, Renu, Harrison, Blair A., Duque, Diana, Bavananthasivam, Jegarubee, Deschatelets, Lise, Hemraz, Usha D., Régnier, Sophie, Durocher, Yves, McCluskie, Michael J.

“…With the continued transmission of SARS‐CoV‐2 across widely vaccinated populations, it remains important to develop new vaccines and vaccination strategies…”
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Effect of Chiral Purity on Adjuvanticity of Archaeol-Based Glycolipids by Régnier, Sophie, Lam, Edmond, Vasquez, Vinicio, Martinez-Farina, Camilo F., Stark, Felicity C., Agbayani, Gerard, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Akache, Bassel, McCluskie, Michael J., Hemraz, Usha D.

“…Archaeosomes composed of sulfated lactosyl archaeol (SLA) glycolipids from stereoisomerically pure archaeol (1) are vaccine adjuvants that can boost…”
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Amine-decorated nanocrystalline cellulose surfaces: synthesis, characterization, and surface properties by Hemraz, Usha D, Boluk, Yaman, Sunasee, Rajesh

“…In this present work, terminal amino-functionalized nanocrystalline cellulose derivatives were prepared using a simple two-step protecting group-free protocol…”
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Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concern by Renner, Tyler M, Akache, Bassel, Stuible, Matthew, Rohani, Nazanin, Cepero-Donates, Yuneivy, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A, Baardsnes, Jason, Koyuturk, Izel, Hill, Jennifer J, Hemraz, Usha D, Régnier, Sophie, Lenferink, Anne E G, Durocher, Yves, McCluskie, Michael J

“…Liposomes composed of sulfated lactosyl archaeol (SLA) have been shown to be a safe and effective vaccine adjuvant with a multitude of antigens in preclinical…”
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Chiromers: conformation-driven mirror-image supramolecular chirality isomerism identified in a new class of helical rosette nanotubes by Hemraz, Usha D, El-Bakkari, Mounir, Yamazaki, Takeshi, Cho, Jae-Young, Beingessner, Rachel L, Fenniri, Hicham

“…Rosette nanotubes are biologically inspired nanostructures, formed through the hierarchical organization of a hybrid DNA base analogue (G∧C), which features…”
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Mechanistic insight into the induction of cellular immune responses by encapsulated and admixed archaeosome-based vaccine formulations by Agbayani, Gerard, Jia, Yimei, Akache, Bassel, Chandan, Vandana, Iqbal, Umar, Stark, Felicity C., Deschatelets, Lise, Lam, Edmond, Hemraz, Usha D., Régnier, Sophie, Krishnan, Lakshmi, McCluskie, Michael J.

“…Archaeosomes are liposomes formulated using total polar lipids (TPLs) or semi-synthetic glycolipids derived from archaea. Conventional archaeosomes with…”
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Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern by Akache, Bassel, Renner, Tyler M., Stuible, Matthew, Rohani, Nazanin, Cepero-Donates, Yuneivy, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Gervais, Christian, Hill, Jennifer J., Hemraz, Usha D., Lam, Edmond, Régnier, Sophie, Lenferink, Anne E. G., Durocher, Yves, McCluskie, Michael J.

“…Using our strongly immunogenic SmT1 SARS-CoV-2 spike antigen platform, we developed antigens based on the Beta & Delta variants of concern (VOC). These…”
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Tuning cell adhesion on titanium with osteogenic rosette nanotubes by Zhang, Lijie, Hemraz, Usha D., Fenniri, Hicham, Webster, Thomas J.

“…Self‐assembled rosette nanotubes (RNTs), obtained from a twin G∧C base functionalized with lysine‐arginine‐serine‐arginine [KRSR–(G∧C)2], were designed and…”
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Self-assembled rosette nanotubes and poly(2-hydroxyethyl methacrylate) hydrogels promote skin cell functions by Sun, Linlin, Li, Dongni, Hemraz, Usha D., Fenniri, Hicham, Webster, Thomas J.

“…The next generation skin of wound healing materials should stimulate skin regeneration by actively promoting appropriate cellular adhesion and proliferation…”
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