Search Results - "Hemphill, Matthew A."
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Traumatic Brain Injury and the Neuronal Microenvironment: A Potential Role for Neuropathological Mechanotransduction
Published in Neuron (Cambridge, Mass.) (18-03-2015)“…Traumatic brain injury (TBI) is linked to several pathologies for which there is a lack of understanding of disease mechanisms and therapeutic strategies. To…”
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Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip
Published in Journal of neurophysiology (01-03-2017)“…Brain in vitro models are critically important to developing our understanding of basic nervous system cellular physiology, potential neurotoxic effects of…”
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Environmental Consistency Determines the Rate of Motor Adaptation
Published in Current biology (19-05-2014)“…The motor system has the remarkable ability not only to learn but also to learn how fast it should learn. However, the mechanisms behind this ability are not…”
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Smartphone-enabled optofluidic exosome diagnostic for concussion recovery
Published in Scientific reports (08-08-2016)“…A major impediment to improving the treatment of concussion is our current inability to identify patients that will experience persistent problems after the…”
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Blast-induced phenotypic switching in cerebral vasospasm
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2011)“…Vasospasm of the cerebrovasculature is a common manifestation of blast-induced traumatic brain injury (bTBI) reported among combat casualties in the conflicts…”
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A possible role for integrin signaling in diffuse axonal injury
Published in PloS one (22-07-2011)“…Over the past decade, investigators have attempted to establish the pathophysiological mechanisms by which non-penetrating injuries damage the brain. Several…”
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Diagnostic tools for evaluating the impact of Focal Axonal Swellings arising in neurodegenerative diseases and/or traumatic brain injury
Published in Journal of neuroscience methods (30-09-2015)“…•Focal Axonal Swellings (FAS) are pathological features of several brain disorders.•The shape of the FAS play crucial role in spike train propagation…”
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Concussion increases CA1 activity during prolonged inactivity in a familiar environment
Published in Experimental neurology (01-12-2020)“…Although hippocampal damage plays a key role in impairments after concussion, differences in hippocampal information processing during recovery are unknown…”
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