Search Results - "Hemmings Jr, HC"
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Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats
Published in British journal of pharmacology (01-02-2010)“…Background and purpose: Results from several studies point to voltage‐gated Na+ channels as potential mediators of the immobility produced by inhaled…”
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2
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution
Published in The Journal of neuroscience (01-05-1986)“…Rabbit antisera and mouse monoclonal antibodies have been prepared to bovine DARPP-32 (dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein, Mr…”
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3
Development of a dopamine- and cyclic adenosine 3':5'-monophosphate- regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation
Published in The Journal of neuroscience (01-07-1987)“…The development of a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein with an apparent Mr of 32,000 (DARPP-32) has been investigated in the…”
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4
Isoform-selective effects of isoflurane on voltage-gated Na+channels
Published in Anesthesiology (Philadelphia) (01-07-2007)“…Voltage-gated Na channels modulate membrane excitability in excitable tissues. Inhibition of Na channels has been implicated in the effects of volatile…”
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5
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
Published in Nature (London) (09-12-1999)“…The physiological state of the cell is controlled by signal transduction mechanisms which regulate the balance between protein kinase and protein phosphatase…”
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6
Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K super(+) channel, TREK-1
Published in British journal of pharmacology (01-11-2007)“…Background and purpose: Deletion of TREK-1, a two-pore domain K super(+) channel (K sub(2P)) activated by volatile anaesthetics, reduces volatile anaesthetic…”
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7
Effects of anticonvulsants on veratridine- and KCl-evoked glutamate release from rat cortical synaptosomes
Published in Neuroscience letters (03-12-1999)“…We compared the effects of three conventional (phenytoin, carbamazepine and phenobarbital) and three novel (BW 1003C87, lamotrigine and riluzole)…”
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The dopaminergic innervation of the pigeon telencephalon: distribution of DARPP-32 and co-occurrence with glutamate decarboxylase and tyrosine hydroxylase
Published in Neuroscience (01-04-1998)“…Dopaminergic axons arising from midbrain nuclei innervate the mammalian and avian telencephalon with heterogeneous regional and laminar distributions. In…”
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9
Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain
Published in Journal of comparative neurology (1911) (10-11-1997)“…The distributions of dopamine D1 receptors, dopaminoceptive neurons, and catecholaminergic fibers were investigated in the forebrain of the domestic chick by…”
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10
General anesthetic effects on protein kinase C
Published in Toxicology letters (23-11-1998)“…(1) Protein kinase C is a family of phospholipid-dependent protein kinases which are involved in the regulation of diverse cellular functions. (2) Evidence is…”
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11
Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks
Published in Journal of chemical neuroanatomy (01-09-2004)“…The striatum is reciprocally connected to the brainstem dopaminergic nuclei and receives a strong dopaminergic input. In the present study the spatial relation…”
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12
Distribution of DARPP-32 immunoreactive structures in the quail brain: anatomical relationship with dopamine and aromatase
Published in Journal of chemical neuroanatomy (2001)“…We recently demonstrated that dopamine (DA) as well as different DA receptor agonists and antagonists are able to decrease within a few minutes the aromatase…”
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13
Opposing Changes in Phosphorylation of Specific Sites in Synapsin I During Ca super(2+)-Dependent Glutamate Release in Isolated Nerve Terminals
Published in The Journal of neuroscience (01-01-2001)“…Synapsins are major neuronal phosphoproteins involved in regulation of neurotransmitter release. Synapsins are well established targets for multiple protein…”
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14
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
Published in Neuropharmacology (01-08-2000)“…ARPP-21 is a cyclic AMP-regulated phosphoprotein of M r 21 kDa that is enriched in the cell bodies and terminals of medium-sized spiny neurons in the basal…”
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15
Inhibition by propofol of [3H]‐batrachotoxinin‐A 20‐α‐benzoate binding to voltage‐dependent sodium channels in rat cortical synaptosomes
Published in British journal of pharmacology (01-12-1996)“…1 Propofol (2,6 di‐isopropylphenol), an intravenous general anaesthetic, blocks voltage‐dependent Na+ channels (Na+ channels). In this study the interaction…”
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DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1
Published in Nature (London) (01-01-1984)“…The neurotransmitter dopamine has been demonstrated by biochemical, histochemical and immunocytochemical techniques to be unevenly distributed in the mammalian…”
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Specificity of Protein Kinase Inhibitor Peptides and Induction of Long-Term Potentiation
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-1994)“…Previous studies have used synthetic peptide analogs, corresponding to sequences within the pseudosubstrate domain of protein kinase C (PKC) or the…”
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Protein Kinases in the Brain
Published in Annual review of biochemistry (01-01-1985)Get full text
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19
Role of protein phosphorylation in neuronal signal transduction
Published in The FASEB journal (01-03-1989)“…Protein phosphorylation is involved in the regulation of a wide variety of physiological processes in the nervous system. Studies in which purified protein…”
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DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization
Published in The Journal of neuroscience (01-01-1984)“…Immunocytochemical studies have been carried out to determine the regional and cellular distribution of DARPP-32, a protein the phosphorylation of which can be…”
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