Search Results - "Hemmer, Lucas W"
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Hybrid dysgenesis in Drosophila virilis results in clusters of mitotic recombination and loss-of-heterozygosity but leaves meiotic recombination unaltered
Published in Mobile DNA (15-02-2020)“…Transposable elements (TEs) are endogenous mutagens and their harmful effects are especially evident in syndromes of hybrid dysgenesis. In , hybrid dysgenesis…”
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Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila
Published in PLoS biology (21-11-2024)“…Centromeres reside in rapidly evolving, repeat-rich genomic regions, despite their essential function in chromosome segregation. Across organisms, centromeres…”
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Holding it together: rapid evolution and positive selection in the synaptonemal complex of Drosophila
Published in BMC evolutionary biology (05-05-2016)“…The synaptonemal complex (SC) is a highly conserved meiotic structure that functions to pair homologs and facilitate meiotic recombination in most eukaryotes…”
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What Drives Positive Selection in the Drosophila piRNA Machinery? The Genomic Autoimmunity Hypothesis
Published in The Yale journal of biology & medicine (01-12-2016)“…In animals, PIWI-interacting RNAs (piRNAs) play a crucial role in genome defense. Moreover, because piRNAs can be maternally transmitted, they contribute to…”
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Journal Article -
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What Drives Positive Selection in the Drosophila piRNA Machinery? The Genomic Autoimmunity Hypothesis
Published in The Yale journal of biology & medicine (07-04-2017)“…In animals, PIWI-interacting RNAs (piRNAs) play a crucial role in genome defense. Moreover, because piRNAs can be maternally transmitted, they contribute to…”
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Journal Article -
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The Evolution of Recombination Landscapes and Mechanisms in Drosophila in Light of Intragenomic Conflict
Published 01-01-2018“…Sex and recombination are ubiquitous across the vast majority of life on earth. In eukaryotes, recombination during meiosis yields new variation that selection…”
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Dissertation