Search Results - "Hemingway, Janet"
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The impact of pyrethroid resistance on the efficacy of insecticide-treated bed nets against African anopheline mosquitoes: systematic review and meta-analysis
Published in PLoS medicine (01-03-2014)“…Pyrethroid insecticide-treated bed nets (ITNs) help contribute to reducing malaria deaths in Africa, but their efficacy is threatened by insecticide resistance…”
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Averting a malaria disaster: will insecticide resistance derail malaria control?
Published in The Lancet (British edition) (23-04-2016)“…Summary World Malaria Day 2015 highlighted the progress made in the development of new methods of prevention (vaccines and insecticides) and treatment (single…”
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Evolution of insecticide resistance and its mechanisms in Anopheles stephensi in the WHO Eastern Mediterranean Region
Published in Malaria journal (17-07-2020)“…While Iran is on the path to eliminating malaria, the disease with 4.9 million estimated cases and 9300 estimated deaths in 2018 remains a serious health…”
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Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7
Published in Proceedings of the National Academy of Sciences - PNAS (23-02-2016)“…The artemisinin (ART)-based antimalarials have contributed significantly to reducing global malaria deaths over the past decade, but we still do not know how…”
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single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector
Published in Genome biology (01-01-2014)“…BACKGROUND: Metabolic resistance to insecticides is the biggest threat to the continued effectiveness of malaria vector control. However, its underlying…”
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Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria?
Published in PLoS biology (02-03-2016)“…Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development…”
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Mapping trends in insecticide resistance phenotypes in African malaria vectors
Published in PLoS biology (25-06-2020)“…Mitigating the threat of insecticide resistance in African malaria vector populations requires comprehensive information about where resistance occurs, to what…”
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malERA: An updated research agenda for malaria elimination and eradication
Published in PLoS medicine (30-11-2017)“…Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are…”
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An economic evaluation of vector control in the age of a dengue vaccine
Published in PLoS neglected tropical diseases (01-08-2017)“…Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with a 30-fold increase in the number of cases reported since 1960. The economic cost of…”
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Core commitments for field trials of gene drive organisms
Published in Science (American Association for the Advancement of Science) (18-12-2020)“…We must ensure that trials are scientifically, politically, and socially robust, publicly accountable, and widely transparent Gene drive organisms (GDOs),…”
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Insecticide Resistance in Insect Vectors of Human Disease
Published in Annual review of entomology (01-01-2000)“…Insecticide resistance is an increasing problem in many insect vectors of disease. Our knowledge of the basic mechanisms underlying resistance to commonly used…”
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Genomic Footprints of Selective Sweeps from Metabolic Resistance to Pyrethroids in African Malaria Vectors Are Driven by Scale up of Insecticide-Based Vector Control
Published in PLoS genetics (02-02-2017)“…Insecticide resistance in mosquito populations threatens recent successes in malaria prevention. Elucidating patterns of genetic structure in malaria vectors…”
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Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana
Published in Proceedings of the National Academy of Sciences - PNAS (17-04-2012)“…In the last decade there have been marked reductions in malaria incidence in sub-Saharan Africa. Sustaining these reductions will rely upon insecticides to…”
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Lessons from the past: managing insecticide resistance in malaria control and eradication programmes
Published in The Lancet infectious diseases (01-06-2008)“…Summary The distribution of insecticide-treated bednets to help combat the burden of malaria in sub-Saharan Africa has accelerated in the past 5 years…”
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DDT-based indoor residual spraying suboptimal for visceral leishmaniasis elimination in India
Published in Proceedings of the National Academy of Sciences - PNAS (14-07-2015)“…Indoor residual spraying (IRS) is used to control visceral leishmaniasis (VL) in India, but it is poorly quality assured. Quality assurance was performed in…”
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Country-level operational implementation of the Global Plan for Insecticide Resistance Management
Published in Proceedings of the National Academy of Sciences - PNAS (04-06-2013)“…Malaria control is reliant on the use of long-lasting pyrethroid-impregnated nets and/or indoor residual spraying (IRS) of insecticide. The rapid selection and…”
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The molecular basis of two contrasting metabolic mechanisms of insecticide resistance
Published in Insect Biochemistry and Molecular Biology (01-11-2000)“…The esterase-based insecticide resistance mechanisms characterised to date predominantly involve elevation of activity through gene amplification allowing…”
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global map of dominant malaria vectors
Published in Parasites & vectors (04-04-2012)“…BACKGROUND: Global maps, in particular those based on vector distributions, have long been used to help visualise the global extent of malaria. Few, however,…”
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Impact of pyrethroid resistance on operational malaria control in Malawi
Published in Proceedings of the National Academy of Sciences - PNAS (20-11-2012)“…The impact of insecticide resistance on insect-borne disease programs is difficult to quantify. The possibility of eliminating malaria in high-transmission…”
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The molecular basis of insecticide resistance in mosquitoes
Published in Insect biochemistry and molecular biology (01-07-2004)“…Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being…”
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