Search Results - "Hembram, Krushna Chandra"
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Advances in preparation and characterization of chitosan nanoparticles for therapeutics
Published in Artificial cells, nanomedicine, and biotechnology (02-01-2016)“…Polymers have been largely explored for the preparation of nanoparticles due to ease of preparation and modification, large gene/drug loading capacity, and…”
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PARP inhibitor Olaparib Enhances the Apoptotic Potentiality of Curcumin by Increasing the DNA Damage in Oral Cancer Cells through Inhibition of BER Cascade
Published in Pathology oncology research (01-10-2020)“…Although Olaparib (Ola, a PARP-inhibitor), in combination with other chemotherapeutic agents, was clinically approved to treat prostate cancer, but…”
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Targeting signaling pathways in cancer stem cells: A potential approach for developing novel anti-cancer therapeutics
Published in International review of cell and molecular biology (2024)“…Cancer stem cells (CSCs) have emerged as prime players in the intricate landscape of cancer development, progression, and resistance to traditional treatments…”
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Nano formulated Resveratrol inhibits metastasis and angiogenesis by reducing inflammatory cytokines in oral cancer cells by targeting tumor associated macrophages
Published in The Journal of nutritional biochemistry (01-06-2021)“…Tumor associated macrophages in the tumor microenvironment secrete multiple cytokines, which regulate cancer cells growth and invasiveness. We systematically…”
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PARP inhibitor Veliparib (ABT-888) enhances the anti-angiogenic potentiality of Curcumin through deregulation of NECTIN-4 in oral cancer: Role of nitric oxide (NO)
Published in Cellular signalling (01-04-2021)“…Concurrent use of DNA damaging agents with PARP inhibitors contribute to the effectiveness of the anticancer therapy. But there is a dearth of reports on the…”
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Quinacrine Based Gold Hybrid Nanoparticles Caused Apoptosis through Modulating Replication Fork in Oral Cancer Stem Cells
Published in Molecular pharmaceutics (06-07-2020)“…The presence of cancer stem cells (CSCs) in the tumor microenvironment is responsible for the development of chemoresistance and recurrence of cancer. Our…”
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Comparative and Mechanistic Study on the Anticancer Activity of Quinacrine-Based Silver and Gold Hybrid Nanoparticles in Head and Neck Cancer
Published in Molecular pharmaceutics (01-07-2019)“…Using oral cancer cells (in vitro) and in vivo xenograft mice model, we have systematically studied the detailed mechanism of anticancer activity of…”
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Quinacrine based gold hybrid nanoparticle caused apoptosis through modulating replication fork in oral cancer stem cells
Published in Molecular pharmaceutics (14-05-2020)“…Presence of cancer stem cells (CSCs) in tumor micro environment is responsible for development of chemo-resistance and recurrence of cancer. Our previous…”
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