Search Results - "Helsell, Cole V. M"

Membrane curvature sensing and symmetry breaking of the M2 proton channel from Influenza A by Lincoff, James, Helsell, Cole V M, Marcoline, Frank V, Natale, Andrew M, Grabe, Michael

“…The M2 proton channel aids in the exit of mature influenza viral particles from the host plasma membrane through its ability to stabilize regions of high…”
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Understanding Thermosensitive Transient Receptor Potential Channels as Versatile Polymodal Cellular Sensors by Hilton, Jacob K, Rath, Parthasarathi, Helsell, Cole V. M, Beckstein, Oliver, Van Horn, Wade D

“…Transient receptor potential (TRP) ion channels are eukaryotic polymodal sensors that function as molecular cellular signal integrators. TRP family members…”
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Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation by Sisco, Nicholas J., Helsell, Cole V. M., Van Horn, Wade D.

“…TRPM8 is a member of the transient receptor potential ion channel family where it functions as a cold and pain sensor in humans and other higher organisms…”
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Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP 2 Suggest a Mechanism for Regulation by Sisco, Nicholas J, Helsell, Cole V M, Van Horn, Wade D

“…TRPM8 is a member of the transient receptor potential ion channel family where it functions as a cold and pain sensor in humans and other higher organisms…”
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Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance by Mavor, David, Barlow, Kyle A, Asarnow, Daniel, Birman, Yuliya, Britain, Derek, Chen, Weilin, Green, Evan M, Kenner, Lillian R, Mensa, Bruk, Morinishi, Leanna S, Nelson, Charlotte A, Poss, Erin M, Suresh, Pooja, Tian, Ruilin, Arhar, Taylor, Ary, Beatrice E, Bauer, David P, Bergman, Ian D, Brunetti, Rachel M, Chio, Cynthia M, Dai, Shizhong A, Dickinson, Miles S, Elledge, Susanna K, Helsell, Cole V M, Hendel, Nathan L, Kang, Emily, Kern, Nadja, Khoroshkin, Matvei S, Kirkemo, Lisa L, Lewis, Greyson R, Lou, Kevin, Marin, Wesley M, Maxwell, Alison M, McTigue, Peter F, Myers-Turnbull, Douglas, Nagy, Tamas L, Natale, Andrew M, Oltion, Keely, Pourmal, Sergei, Reder, Gabriel K, Rettko, Nicholas J, Rohweder, Peter J, Schwarz, Daniel M C, Tan, Sophia K, Thomas, Paul V, Tibble, Ryan W, Town, Jason P, Tsai, Mary K, Ugur, Fatima S, Wassarman, Douglas R, Wolff, Alexander M, Wu, Taia S, Bogdanoff, Derek, Li, Jennifer, Thorn, Kurt S, O'Conchúir, Shane, Swaney, Danielle L, Chow, Eric D, Madhani, Hiten D, Redding, Sy, Bolon, Daniel N, Kortemme, Tanja, DeRisi, Joseph L, Kampmann, Martin, Fraser, James S

“…Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection…”
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