Search Results - "Helmut Niller, Hans"

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018-2020 by Eisermann, Philip, Rubbenstroth, Dennis, Cadar, Daniel, Thomé-Bolduan, Corinna, Eggert, Petra, Schlaphof, Alexander, Leypoldt, Frank, Stangel, Martin, Fortwängler, Thorsten, Hoffmann, Florian, Osterman, Andreas, Zange, Sabine, Niller, Hans-Helmut, Angstwurm, Klemens, Pörtner, Kirsten, Frank, Christina, Wilking, Hendrik, Beer, Martin, Schmidt-Chanasit, Jonas, Tappe, Dennis

“…Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1). We…”
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The neuropathology of fatal encephalomyelitis in human Borna virus infection by Liesche, Friederike, Ruf, Viktoria, Zoubaa, Saida, Kaletka, Gwendolyn, Rosati, Marco, Rubbenstroth, Dennis, Herden, Christiane, Goehring, Lutz, Wunderlich, Silke, Wachter, Miguel Frederic, Rieder, Georg, Lichtmannegger, Ines, Permanetter, Willibald, Heckmann, Josef G., Angstwurm, Klemens, Neumann, Bernhard, Märkl, Bruno, Haschka, Stefan, Niller, Hans-Helmut, Schmidt, Barbara, Jantsch, Jonathan, Brochhausen, Christoph, Schlottau, Kore, Ebinger, Arnt, Hemmer, Bernhard, Riemenschneider, Markus J., Herms, Jochen, Beer, Martin, Matiasek, Kaspar, Schlegel, Jürgen

“…After many years of controversy, there is now recent and solid evidence that classical Borna disease virus 1 (BoDV-1) can infect humans. On the basis of six…”
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DNA extraction from clotted blood in genotyping quality by Stanzick, Kira J, Simon, Josef, Zimmermann, Martina E, Schachtner, Michael, Peterhoff, David, Niller, Hans-Helmut, Überla, Klaus, Wagner, Ralf, Heid, Iris M, Stark, Klaus J

“…DNA extraction from frozen blood clots is challenging. Here, the authors applied QIAGEN Clotspin Baskets and the Gentra Puregene Blood Kit for DNA extraction…”
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Manufacturing of convalescent plasma of COVID-19 patients: Aspects of quality by Hähnel, Viola, Peterhoff, David, Bäuerlein, Veronika, Brosig, Andreas-Michael, Pamler, Irene, Johnson, Christian, Bica, Adelina, Totir, Monica, Ossner, Thomas, Stemmer, Barbara, Toelge, Martina, Schütz, Anja, Niller, Hans-Helmut, Schmidt, Barbara, Wagner, Ralf, Gessner, André, Burkhard, Ralph, Offner, Robert

“…The ongoing coronavirus disease 2019 (COVID-19) pandemic emerged in December 2019. Convalescent plasma represents a promising COVID-19 treatment. Here, we…”
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Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County-Results from a Population-Based Longitudinal Study in Germany by Einhauser, Sebastian, Peterhoff, David, Beileke, Stephanie, Günther, Felix, Niller, Hans-Helmut, Steininger, Philipp, Knöll, Antje, Korn, Klaus, Berr, Melanie, Schütz, Anja, Wiegrebe, Simon, Stark, Klaus J, Gessner, André, Burkhardt, Ralph, Kabesch, Michael, Schedl, Holger, Küchenhoff, Helmut, Pfahlberg, Annette B, Heid, Iris M, Gefeller, Olaf, Überla, Klaus, Wagner, Ralf

“…Herein, we provide results from a prospective population-based longitudinal follow-up (FU) SARS-CoV-2 serosurveillance study in Tirschenreuth, the county which…”
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Comparative Immunogenicity of COVID-19 Vaccines in a Population-Based Cohort Study with SARS-CoV-2-Infected and Uninfected Participants by Peterhoff, David, Einhauser, Sebastian, Beileke, Stephanie, Niller, Hans-Helmut, Günther, Felix, Schachtner, Michael, Asbach, Benedikt, Steininger, Philipp, Tenbusch, Matthias, Peter, Antonia S, Gessner, Andre, Burkhardt, Ralph, Heid, Iris M, Wagner, Ralf, Überla, Klaus

“…To assess vaccine immunogenicity in non-infected and previously infected individuals in a real-world scenario, SARS-CoV-2 antibody responses were determined…”
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Performance of T-Track® SARS-CoV-2, an Innovative Dual Marker RT-qPCR-Based Whole-Blood Assay for the Detection of SARS-CoV-2-Reactive T Cells by Kanis, Franziska M, Meier, Johannes P, Guldan, Harald, Niller, Hans-Helmut, Dahm, Michael, Dansard, Alexander, Zander, Thomas, Struck, Friedhelm, Soutschek, Erwin, Deml, Ludwig, Möbus, Selina, Barabas, Sascha

“…T-cell immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a central role in the control of the virus. In this study, we…”
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Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite by Berger, Raffaela S, Wachsmuth, Christian J, Waldhier, Magdalena C, Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar, Niller, Hans-Helmut, Bumes, Elisabeth, Hau, Peter, Proescholdt, Martin, Gronwald, Wolfram, Heuser, Michael, Kreutz, Marina, Oefner, Peter J, Dettmer, Katja

“…In recent years, onco-metabolites like D-2-hydroxyglutarate, which is produced in isocitrate dehydrogenase-mutated tumors, have gained increasing interest…”
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Transcriptional Regulation of CHI3L1, a Marker Gene for Late Stages of Macrophage Differentiation by Rehli, Michael, Niller, Hans-Helmut, Ammon, Christoph, Langmann, Sabine, Schwarzfischer, Lucia, Andreesen, Reinhard, Krause, Stefan W.

“…The protein product of the CHI3L1 gene, human cartilage 39-kDa glycoprotein (HC-gp39), is a tissue-restricted, chitin-binding lectin and member of glycosyl…”
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Epstein-Barr Virus: Clinical Diagnostics by Niller, Hans-Helmut, Bauer, Georg

“…The vast majority of the human adult population is infected with Epstein-Barr virus (EBV), and the majority of the EBV-infected individuals tolerates the…”
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Regulation and dysregulation of Epstein-Barr virus latency: Implications for the development of autoimmune diseases by Niller, Hans Helmut, Wolf, Hans, Minarovits, Janos

“…Epstein-Barr virus (EBV) is a human herpesvirus hiding in a latent form in memory B cells in the majority of the world population. Although, primary EBV…”
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Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases by Niller, Hans Helmut, Banati, Ferenc, Salamon, Daniel, Minarovits, Janos

“…Latent Epstein-Bar virus genomes undergo epigenetic modifications which are dependent on the respective tissue type and cellular phenotype. These define…”
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Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography by Ebinger, Arnt, Santos, Pauline D., Pfaff, Florian, Dürrwald, Ralf, Kolodziejek, Jolanta, Schlottau, Kore, Ruf, Viktoria, Liesche-Starnecker, Friederike, Ensser, Armin, Korn, Klaus, Ulrich, Reiner, Fürstenau, Jenny, Matiasek, Kaspar, Hansmann, Florian, Seuberlich, Torsten, Nobach, Daniel, Müller, Matthias, Neubauer-Juric, Antonie, Suchowski, Marcel, Bauswein, Markus, Niller, Hans-Helmut, Schmidt, Barbara, Tappe, Dennis, Cadar, Daniel, Homeier-Bachmann, Timo, Haring, Viola C., Pörtner, Kirsten, Frank, Christina, Mundhenk, Lars, Hoffmann, Bernd, Herms, Jochen, Baumgärtner, Wolfgang, Nowotny, Norbert, Schlegel, Jürgen, Ulrich, Rainer G., Beer, Martin, Rubbenstroth, Dennis

“…Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over…”
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Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease by Rauch, Jessica, Steffen, Johanna Friederike, Muntau, Birgit, Gisbrecht, Jana, Pörtner, Kirsten, Herden, Christiane, Niller, Hans Helmut, Bauswein, Markus, Rubbenstroth, Dennis, Mehlhoop, Ute, Allartz, Petra, Tappe, Dennis

“…Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case…”
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Epigenetic dysregulation of the host cell genome in Epstein–Barr virus-associated neoplasia by Niller, Hans Helmut, Wolf, Hans, Minarovits, Janos

“…Abstract Epstein–Barr virus (EBV), a human herpesvirus, is associated with a wide variety of malignant tumors. The expression of the latent viral RNAs is under…”
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Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany by Bauswein, Markus, Eidenschink, Lisa, Knoll, Gertrud, Neumann, Bernhard, Angstwurm, Klemens, Zoubaa, Saida, Riemenschneider, Markus J, Lampl, Benedikt M J, Pregler, Matthias, Niller, Hans Helmut, Jantsch, Jonathan, Gessner, André, Eberhardt, Yvonne, Huppertz, Gunnar, Schramm, Torsten, Kühn, Stefanie, Koller, Michael, Drasch, Thomas, Ehrl, Yvonne, Banas, Bernhard, Offner, Robert, Schmidt, Barbara, Banas, Miriam C

“…More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region…”
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Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020 by Wagner, Ralf, Peterhoff, David, Beileke, Stephanie, Günther, Felix, Berr, Melanie, Einhauser, Sebastian, Schütz, Anja, Niller, Hans Helmut, Steininger, Philipp, Knöll, Antje, Tenbusch, Matthias, Maier, Clara, Korn, Klaus, Stark, Klaus J., Gessner, André, Burkhardt, Ralph, Kabesch, Michael, Schedl, Holger, Küchenhoff, Helmut, Pfahlberg, Annette B., Heid, Iris M., Gefeller, Olaf, Überla, Klaus

“…SARS-CoV-2 infection fatality ratios (IFR) remain controversially discussed with implications for political measures. The German county of Tirschenreuth…”
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Tick-borne encephalitis virus neutralization by high dose intravenous immunoglobulin by Elsterova, Jana, Palus, Martin, Sirmarova, Jana, Kopecky, Jan, Niller, Hans Helmut, Ruzek, Daniel

“…Tick-borne encephalitis (TBE) is a potentially lethal neuroinfection in humans, caused by TBE virus (TBEV). Currently, there are no approved therapeutic agents…”
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IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study by Eidenschink, Lisa, Knoll, Gertrud, Tappe, Dennis, Offner, Robert, Drasch, Thomas, Ehrl, Yvonne, Banas, Bernhard, Banas, Miriam C, Niller, Hans Helmut, Gessner, André, Köstler, Josef, Lampl, Benedikt M J, Pregler, Matthias, Völkl, Melanie, Kunkel, Jürgen, Neumann, Bernhard, Angstwurm, Klemens, Schmidt, Barbara, Bauswein, Markus

“…More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern…”
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Omicron’s binding to sotrovimab, casirivimab, imdevimab, CR3022, and sera from previously infected or vaccinated individuals by Mader, Anna-Lena, Tydykov, Leonid, Glück, Vivian, Bertok, Manuela, Weidlich, Tanja, Gottwald, Christine, Stefl, Alexa, Vogel, Matthias, Plentz, Annelie, Köstler, Josef, Salzberger, Bernd, Wenzel, Jürgen J., Niller, Hans Helmut, Jantsch, Jonathan, Wagner, Ralf, Schmidt, Barbara, Glück, Thomas, Gessner, André, Peterhoff, David

“…SARS-CoV-2 Omicron is the first pandemic variant of concern exhibiting an abrupt accumulation of mutations particularly in the receptor-binding domain that is…”
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