Search Results - "Helms, Jill"

Multiscale analysis of craniomaxillofacial bone repair: A preclinical mini‐pig study by Ticha, Pavla, Pilawski, Igor, Helms, Jill A.

“…Background The rate of reparative osteogenesis controls when an implant is sufficiently stable as to allow functional loading. Using a mini pig model, the rate…”
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Drill Hole Models to Investigate Bone Repair by Li, Zhijun, Helms, Jill A

“…Our understanding of the mechanisms underlying fracture healing is rapidly developing and is contributing to new therapeutic strategies to enhance repair. To…”
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Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression by Li, Lingjie, Liu, Bo, Wapinski, Orly L., Tsai, Miao-Chih, Qu, Kun, Zhang, Jiajing, Carlson, Jeff C., Lin, Meihong, Fang, Fengqin, Gupta, Rajnish A., Helms, Jill A., Chang, Howard Y.

“…Long noncoding RNAs (lncRNAs) are thought to be prevalent regulators of gene expression, but the consequences of lncRNA inactivation in vivo are mostly…”
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A Correlation between Wnt/Beta-catenin Signaling and the Rate of Dentin Secretion by Zhao, Yuan, Yuan, Xue, Bellido, Teresita, Helms, Jill A.

“…Odontoblasts produce dentin throughout life and in response to trauma. The purpose of this study was to identify the roles of endogenous Wnt signaling in…”
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A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression by Wang, Kevin C., Yang, Yul W., Liu, Bo, Sanyal, Amartya, Corces-Zimmerman, Ryan, Chen, Yong, Lajoie, Bryan R., Protacio, Angeline, Flynn, Ryan A., Gupta, Rajnish A., Wysocka, Joanna, Lei, Ming, Dekker, Job, Helms, Jill A., Chang, Howard Y.

“…Long-range genetic regulation A major question in developmental biology is how functionally related groups of genes are switched on at the right time and in…”
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Differentiation of multipotent vascular stem cells contributes to vascular diseases by Tang, Zhenyu, Wang, Aijun, Yuan, Falei, Yan, Zhiqiang, Liu, Bo, Chu, Julia S., Helms, Jill A., Li, Song

“…It is generally accepted that the de-differentiation of smooth muscle cells, from the contractile to the proliferative/synthetic phenotype, has an important…”
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The effect of osteocyte‐derived RANKL on bone graft remodeling: An in vivo experimental study by Feher, Balazs, Kampleitner, Carina, Heimel, Patrick, Tangl, Stefan, Helms, Jill A., Kuchler, Ulrike, Gruber, Reinhard

“…Objectives Autologous bone is considered the gold standard for grafting, yet it suffers from a tendency to undergo resorption over time. While the exact…”
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Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading by Temiyasathit, Sara, Tang, W Joyce, Leucht, Philipp, Anderson, Charles T, Monica, Stefanie D, Castillo, Alesha B, Helms, Jill A, Stearns, Tim, Jacobs, Christopher R

“…Primary cilia, solitary microtubule-based structures that grow from the centriole and extend into the extracellular space, have increasingly been implicated as…”
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Comment on "Hotair Is Dispensable for Mouse Development" by Li, Lingjie, Helms, Jill A, Chang, Howard Y

“…Lingjie Li Affiliation: Program in Epithelial Biology Stanford University School of Medicine, Stanford, California, United States of America Jill A. Helms…”
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Wnt proteins promote bone regeneration by Minear, Steven, Leucht, Philipp, Jiang, Jie, Liu, Bo, Zeng, Arial, Fuerer, Christophe, Nusse, Roel, Helms, Jill A

“…The Wnt signaling pathway plays a central role in bone development and homeostasis. In most cases, Wnt ligands promote bone growth, which has led to…”
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Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs by Rinn, John L., Kertesz, Michael, Wang, Jordon K., Squazzo, Sharon L., Xu, Xiao, Brugmann, Samantha A., Goodnough, L. Henry, Helms, Jill A., Farnham, Peggy J., Segal, Eran, Chang, Howard Y.

“…Noncoding RNAs (ncRNA) participate in epigenetic regulation but are poorly understood. Here we characterize the transcriptional landscape of the four human HOX…”
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Interspecies comparison of alveolar bone biology: Tooth extraction socket healing in mini pigs and mice by Pan, Jie, Pilawski, Igor, Yuan, Xue, Arioka, Masaki, Ticha, Pavla, Tian, Ye, Helms, Jill A.

“…Background in an effort to identify and validate which animal models are best suited for dental implant research, we used multiscale analyses to examine tooth…”
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Wnt signaling and injury repair by Whyte, Jemima L, Smith, Andrew A, Helms, Jill A

“…Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell…”
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Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration by Leucht, Philipp, Kim, Jae-Beom, Amasha, Raimy, James, Aaron W, Girod, Sabine, Helms, Jill A

“…The fetal skeleton arises from neural crest and from mesoderm. Here, we provide evidence that each lineage contributes a unique stem cell population to the…”
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Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development by ten Berge, Derk, Brugmann, Samantha A, Helms, Jill A, Nusse, Roel

“…A fundamental question in developmental biology is how does an undifferentiated field of cells acquire spatial pattern and undergo coordinated differentiation?…”
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Cranial neural crest cells on the move: Their roles in craniofacial development by Cordero, Dwight R., Brugmann, Samantha, Chu, Yvonne, Bajpai, Ruchi, Jame, Maryam, Helms, Jill A.

“…The craniofacial region is assembled through the active migration of cells and the rearrangement and sculpting of facial prominences and pharyngeal arches,…”
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Aberrantly elevated Wnt signaling is responsible for cementum overgrowth and dental ankylosis by Wu, Yan, Yuan, Xue, Perez, Kristy C., Hyman, Sydnee, Wang, Liao, Pellegrini, Gretel, Salmon, Benjamin, Bellido, Teresita, Helms, Jill A.

“…Vertebrate teeth are attached to the jawbones using a variety of methods but in mammals, a fibrous connection is the norm. This fibrous periodontal ligament…”
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A novel system exploits bone debris for implant osseointegration by Coyac, Benjamin R., Salvi, Giuseppe, Leahy, Brian, Li, Zhijun, Salmon, Benjamin, Hoffmann, Waldemar, Helms, Jill A.

“…Background Bone debris generated during site preparation is generally evacuated with irrigation; here, we evaluated whether retention of this autologous…”
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Comparative analyses of the soft tissue interfaces around teeth and implants: Insights from a pre‐clinical implant model by Yuan, Xue, Pei, Xibo, Chen, Jinlong, Zhao, Yuan, Brunski, John B., Helms, Jill A.

“…Aim To evaluate the similarities and differences in barrier function of a peri‐implant epithelium (PIE) versus a native junctional epithelium (JE). Materials…”
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Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing by Liu, Chao, Carrera, Robert, Flamini, Vittoria, Kenny, Lena, Cabahug-Zuckerman, Pamela, George, Benson M., Hunter, Daniel, Liu, Bo, Singh, Gurpreet, Leucht, Philipp, Mann, Kenneth A., Helms, Jill A., Castillo, Alesha B.

“…Mechanical loading is an important aspect of post-surgical fracture care. The timing of load application relative to the injury event may differentially…”
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