Search Results - "Helms, Amy W"

Specification of dorsal spinal cord interneurons by Helms, Amy W, Johnson, Jane E

“…To obtain the correct number of each neuronal subtype, there must be mechanisms to control progenitor pool size, and factors that control the differentiation…”
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Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord by Battiste, James, Helms, Amy W, Kim, Euiseok J, Savage, Trisha K, Lagace, Diane C, Mandyam, Chitra D, Eisch, Amelia J, Miyoshi, Goichi, Johnson, Jane E

“…The neural basic helix-loop-helix transcription factor Ascl1 (previously Mash1) is present in ventricular zone cells in restricted domains throughout the…”
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Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons by Helms, Amy W, Battiste, James, Henke, R Michael, Nakada, Yuji, Simplicio, Nicolas, Guillemot, Francois, Johnson, Jane E

“…The dorsal spinal cord contains a diverse array of neurons that connect sensory input from the periphery to spinal cord motoneurons and brain. During…”
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Crossinhibitory Activities of Ngn1 and Math1 Allow Specification of Distinct Dorsal Interneurons by Gowan, Katherine, Helms, Amy W, Hunsaker, Thomas L, Collisson, Tandi, Ebert, Philip J, Odom, Raanan, Johnson, Jane E

“…Distinct classes of neurons are generated from progenitor cells distributed in characteristic dorsoventral patterns in the developing spinal neural tube. We…”
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Distinct activities of Msx1 and Msx3 in dorsal neural tube development by Liu, Ying, Helms, Amy W, Johnson, Jane E

“…Patterning of the dorsal neural tube involves Bmp signaling, which results in activation of multiple pathways leading to the formation of neural crest, roof…”
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Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation by Ebert, Philip J, Timmer, John R, Nakada, Yuji, Helms, Amy W, Parab, Preeti B, Liu, Ying, Hunsaker, Thomas L, Johnson, Jane E

“…Math1 is a basic helix-loop-helix transcription factor expressed in progenitor cells that give rise to dorsal commissural interneurons in the spinal cord,…”
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Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline by Imondi, Ralph, Jevince, Angela R., Helms, Amy W., Johnson, Jane E., Kaprielian, Zaven

“…In vertebrates, spinal commissural axons project along a transverse path toward and across the floor plate (FP). Post-crossing commissural axons alter their…”
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Autoregulation and multiple enhancers control Math1 expression in the developing nervous system by Helms, A W, Abney, A L, Ben-Arie, N, Zoghbi, H Y, Johnson, J E

“…Development of the vertebrate nervous system requires the actions of transcription factors that establish regional domains of gene expression, which results in…”
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Progenitors of dorsal commissural interneurons are defined by MATH1 expression by Helms, A W, Johnson, J E

“…MATH1 is a neural-specific basic helix-loop-helix transcription factor. Members of this family of transcription factors are involved in the development of…”
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Overexpression of MATH1 Disrupts the Coordination of Neural Differentiation in Cerebellum Development by Helms, Amy W., Gowan, Katherine, Abney, Andrew, Savage, Trisha, Johnson, Jane E.

“…An essential role for the bHLH transcription factor MATH1 in the formation of cerebellar granule cells was previously demonstrated in a Math1 null mouse. The…”
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XATH-1, a vertebrate homolog of Drosophila atonal, induces neuronal differentiation within ectodermal progenitors by Kim, P, Helms, A.W, Johnson, J.E, Zimmerman, K

“…XATH-1, a basic/helix-loop-helix transcription factor and a homolog of Drosophila atonal and mammalian MATH-1, is expressed specifically in the dorsal…”
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XATH-1,a Vertebrate Homolog ofDrosophila atonal,Induces Neuronal Differentiation within Ectodermal Progenitors by Kim, Peter, Helms, Amy W., Johnson, Jane E., Zimmerman, Kathryn

“…XATH-1,a basic/helix-loop-helix transcription factor and a homolog ofDrosophila atonaland mammalianMATH-1,is expressed specifically in the dorsal hindbrain…”
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