Search Results - "Hellström, P"

Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides by Falkén, Y, Hellström, P. M, Holst, J. J, Näslund, E

“…Context: Endocrine effects of gastric bypass (GBP) surgery for obesity on glucose homeostasis are not fully understood. Main Objective: The main objective of…”
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One-year outcome in the European multicentre study on iNPH by Klinge, P., Hellström, P., Tans, J., Wikkelsø, C.

“…Objectives To assess the 1‐year outcome after shunt surgery in patients with idiopathic normal pressure hydrocephalus (iNPH). Methods Patients (n = 142) were…”
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A new scale for assessment of severity and outcome in iNPH by Hellström, P., Klinge, P., Tans, J., Wikkelsø, C.

“…Objective To present a new, continuous, calibrated and norm‐based scale for the grading of severity and assessment of treatment outcome in idiopathic normal…”
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Ghrelin Stimulates Gastric Emptying and Hunger in Normal-Weight Humans by Levin, F., Edholm, T., Schmidt, P. T., Grybäck, P., Jacobsson, H., Degerblad, M., Höybye, C., Holst, J. J., Rehfeld, J. F., Hellström, P. M., Näslund, E.

“…Context: Ghrelin is produced primarily by enteroendocrine cells in the gastric mucosa and increases gastric emptying in patients with gastroparesis. Main…”
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International consensus on the diagnosis and management of dumping syndrome by Scarpellini, Emidio, Arts, Joris, Karamanolis, George, Laurenius, Anna, Siquini, Walter, Suzuki, Hidekazu, Ukleja, Andrew, Van Beek, Andre, Vanuytsel, Tim, Bor, Serhat, Ceppa, Eugene, Di Lorenzo, Carlo, Emous, Marloes, Hammer, Heinz, Hellström, Per, Laville, Martine, Lundell, Lars, Masclee, Ad, Ritz, Patrick, Tack, Jan

“…Dumping syndrome is a common but underdiagnosed complication of gastric and oesophageal surgery. We initiated a Delphi consensus process with international…”
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Validation of SmartPill® wireless motility capsule for gastrointestinal transit time: Intra‐subject variability, software accuracy and comparison with video capsule endoscopy by Diaz Tartera, H. O., Webb, D.‐L., Al‐Saffar, A. Kh, Halim, M. A., Lindberg, G., Sangfelt, P., Hellström, P. M.

“…Background There is interest in ultimately combining endoscopy and motility assessments. Gastric emptying (GET), small bowel (SBTT), colon (CTT) and whole gut…”
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Absence of Disproportionately Enlarged Subarachnoid Space Hydrocephalus, a Sharp Callosal Angle, or Other Morphologic MRI Markers Should Not Be Used to Exclude Patients with Idiopathic Normal Pressure Hydrocephalus from Shunt Surgery by Agerskov, S, Wallin, M, Hellström, P, Ziegelitz, D, Wikkelsö, C, Tullberg, M

“…Several studies have evaluated the use of MR imaging markers for the prediction of outcome after shunt surgery in idiopathic normal pressure hydrocephalus with…”
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Clinical trial: colectomy after rescue therapy in ulcerative colitis – 3‐year follow‐up of the Swedish‐Danish controlled infliximab study by Gustavsson, A., Järnerot, G., Hertervig, E., Friis‐Liby, I., Blomquist, L., Karlén, P., Grännö, C., Vilien, M., Ström, M., Verbaan, H., Hellström, P. M., Magnuson, A., Halfvarson, J., Tysk, C.

“…Aliment Pharmacol Ther 2010; 32: 984–989 Summary Background  The long‐term efficacy of infliximab as rescue therapy in steroid‐refractory ulcerative colitis is…”
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Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability by Dahlgren, D., Venczel, M., Ridoux, J.-P., Skjöld, C., Müllertz, A., Holm, R., Augustijns, P., Hellström, P.M., Lennernäs, H.

“…[Display omitted] Accurate in vivo predictions of intestinal absorption of low solubility drugs require knowing their solubility in physiologically relevant…”
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Regional gastrointestinal transit and pH studied in 215 healthy volunteers using the wireless motility capsule: influence of age, gender, study country and testing protocol by Wang, Y. T., Mohammed, S. D., Farmer, A. D., Wang, D., Zarate, N., Hobson, A. R., Hellström, P. M., Semler, J. R., Kuo, B., Rao, S. S., Hasler, W. L., Camilleri, M., Scott, S. M.

“…Summary Background The wireless motility capsule (WMC) offers the ability to investigate luminal gastrointestinal (GI) physiology in a minimally invasive…”
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The progression of doxorubicin-induced intestinal mucositis in rats by Kullenberg, F., Peters, K., Luna-Marco, C., Salomonsson, A., Kopsida, M., Degerstedt, O., Sjöblom, M., Hellström, P. M., Heindryckx, F., Dahlgren, D., Lennernäs, H.

“…Chemotherapy-induced intestinal mucositis is a severe side effect contributing to reduced quality of life and premature death in cancer patients. Despite a…”
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The adaptive metabolic response to exercise-induced weight loss influences both energy expenditure and energy intake by Hopkins, M, Gibbons, C, Caudwell, P, Hellström, P M, Näslund, E, King, N A, Finlayson, G, Blundell, J E

“…Background/objectives: A decline in resting energy expenditure (REE) beyond that predicted from changes in body composition has been noted following…”
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Ventricular Volume Is More Strongly Associated with Clinical Improvement Than the Evans Index after Shunting in Idiopathic Normal Pressure Hydrocephalus by Neikter, J., Agerskov, S., Hellström, P., Tullberg, M., Starck, G., Ziegelitz, D., Farahmand, D.

“…BACKGROUND AND PURPOSE: Ventricular enlargement in idiopathic normal pressure hydrocephalus is often estimated using the Evans index. However, the sensitivity…”
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Pre-operative carbohydrate loading may be used in type 2 diabetes patients by GUSTAFSSON, U. O., NYGREN, J., THORELL, A., SOOP, M., HELLSTRÖM, P. M, LJUNGQVIST, O., HAGSTRÖM-TOFT, E.

“…Background: Post‐operative insulin resistance and hyperglycaemia are associated with an impaired outcome after surgery. Pre‐operative oral carbohydrate loading…”
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Ghrelin receptor agonist (TZP‐101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis by EJSKJAER, N., VESTERGAARD, E. T., HELLSTRÖM, P. M., GORMSEN, L. C., MADSBAD, S., MADSEN, J. L., JENSEN, T. A., PEZZULLO, J. C., CHRISTIANSEN, J. S., SHAUGHNESSY, L., KOSUTIC, G.

“…Summary Background  TZP‐101 is a synthetic, selective ghrelin agonist in development for gastroparesis. Aim  To assess safety and effects of TZP‐101 in…”
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A phase 2a, randomized, double‐blind 28‐day study of TZP‐102 a ghrelin receptor agonist for diabetic gastroparesis by Ejskjaer, N., Wo, J. M., Esfandyari, T., Mazen Jamal, M., Dimcevski, G., Tarnow, L., Malik, R. A., Hellström, P. M., Mondou, E., Quinn, J., Rousseau, F., McCallum, R. W.

“…Background  Gastroparesis causes significant morbidity and treatment options are limited. TZP‐102 a novel, macrocyclic, selective, oral ghrelin receptor…”
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Intravenous ghrelin accelerates postoperative gastric emptying and time to first bowel movement in humans by Falkén, Y., Webb, D.‐L., Abraham‐Nordling, M., Kressner, U., Hellström, P. M., Näslund, E.

“…Background Ghrelin has been shown to stimulate gastric emptying in healthy humans and patients with delayed gastric emptying. The aim of this study is to…”
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Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS by Benno, P., Norin, E., Midtvedt, T., Hellström, P.M.

“…By administering an anaerobic cultivated human intestinal microbiota (ACHIM) via upper gastrointestinal route using endoscopy we aimed to rectify intestinal…”
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Differential incretin effects of GIP and GLP‐1 on gastric emptying, appetite, and insulin‐glucose homeostasis by Edholm, T., Degerblad, M., Grybäck, P., Hilsted, L., Holst, J. J., Jacobsson, H., Efendic, S., Schmidt, P. T., Hellström, P. M.

“…Background  Glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) are major incretins with important effects on…”
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Clinical trial: the glucagon‐like peptide‐1 analogue ROSE‐010 for management of acute pain in patients with irritable bowel syndrome: a randomized, placebo‐controlled, double‐blind study by HELLSTRÖM, P. M., HEIN, J., BYTZER, P., BJÖRNSSÖN, E., KRISTENSEN, J., SCHAMBYE, H.

“…Summary Background  There is currently no treatment available to manage acute pain attacks in IBS patients regardless of subtype. Aims  To evaluate efficacy…”
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