Search Results - "Hellingman, A. A."

Fat Mass Accumulation during Childhood Determines Insulin Sensitivity in Early Adulthood by Leunissen, R. W. J., Oosterbeek, P., Hol, L. K. M., Hellingman, A. A., Stijnen, T., Hokken-Koelega, A. C. S.

“…Background/Objectives: Low birth weight and postnatal catch-up growth have been associated with an increased risk for diabetes mellitus type II (DMII). We…”
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Health-related quality of life after otologic surgical treatment for chronic otitis media: systematic review by Schouwenaar, Esther M. M., Hellingman, Catharine A., Waterval, Jérôme J.

“…ObjectiveThis systematic review aims to describe the impact of otologic surgery as a treatment for chronic otitis media (COM) on the Health-Related Quality of…”
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Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification by Hellingman, Catharine A, Davidson, Esmeralda N Blaney, Koevoet, Wendy, Vitters, Elly L, van den Berg, Wim B, van Osch, Gerjo J V M, van der Kraan, Peter M

“…The aim of this study was to investigate the roles of Smad2/3 and Smad1/5/8 phosphorylation in transforming growth factor-beta-induced chondrogenic…”
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A Prospective Self-Report Survey-Based Cohort Study on Factors That Have an Influence on Tinnitus by Devos, Jana V. P., Janssen, Marcus L. F., Janssen, A. Miranda L., Hellingman, Catharine A., Smit, Jasper V.

“…Background: Limited information is available on factors that affect the burden tinnitus. The aim of this study is to investigate the association between…”
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Evaluating hearing performance with cochlear implants within the same patient using daily randomization and imaging-based fitting - The ELEPHANT study by Lambriks, L J G, van Hoof, M, Debruyne, J A, Janssen, M, Chalupper, J, van der Heijden, K A, Hof, J R, Hellingman, C A, George, E L J, Devocht, E M J

“…Prospective research in the field of cochlear implants is hampered by methodological issues and small sample sizes. The ELEPHANT study presents an alternative…”
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Measuring growth of residual cholesteatoma in subtotal petrosectomy by Hellingman, Catharine A., Logher, Joris L.E., Kammeijer, Quinten, Waterval, Jerome J., Ebbens, Fenna A., van Spronsen, Erik

“…Background: Little is known about the growth rate of cholesteatoma in patients. Objective: Investigate the growth of residual cholesteatoma in subtotal…”
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Chondrogenic priming of human bone marrow stromal cells: a better route to bone repair? by Farrell, Eric, van der Jagt, Olav P, Koevoet, Wendy, Kops, Nicole, van Manen, Christiaan J, Hellingman, Catharine A, Jahr, Holger, O'Brien, Fergal J, Verhaar, Jan A N, Weinans, Harrie, van Osch, Gerjo J V M

“…The use of bioengineered cell constructs for the treatment of bone defects has received much attention of late. Often, bone marrow stromal cells (BMSCs) are…”
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Variations in Surgical Procedures for Hind Limb Ischaemia Mouse Models Result in differences in Collateral Formation by Hellingman, A.A, Bastiaansen, A.J.N.M, de Vries, M.R, Seghers, L, Lijkwan, M.A, Löwik, C.W, Hamming, J.F, Quax, P.H.A

“…Abstract Objective To identify the optimal mouse model for hind limb ischaemia, which offers a therapeutic window that is large enough to detect improvements…”
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Differences in cartilage-forming capacity of expanded human chondrocytes from ear and nose and their gene expression profiles by Hellingman, Catharine A, Verwiel, Eugène T P, Slagt, Inez, Koevoet, Wendy, Poublon, René M L, Nolst-Trenité, Gilbert J, Baatenburg de Jong, Robert J, Jahr, Holger, van Osch, Gerjo J V M

“…The aim of this study was to evaluate the potential of culture-expanded human auricular and nasoseptal chondrocytes as cell source for regeneration of stable…”
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Protease-activated receptor (PAR)2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model by van den Hengel, Lisa G, Hellingman, Alwine A, Nossent, Anne Yael, van Oeveren-Rietdijk, Annemarie M, de Vries, Margreet R, Spek, C Arnold, van Zonneveld, Anton Jan, Reitsma, Pieter H, Hamming, Jaap F, de Boer, Hetty C, Versteeg, Henri H, Quax, Paul H A

“…In collateral development (i.e. arteriogenesis), mononuclear cells are important and exist as a heterogeneous population consisting of pro-inflammatory and…”
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A limited role for regulatory T cells in post‐ischemic neovascularization by Hellingman, A.A., van der Vlugt, L.E.P.M., Lijkwan, M.A., Bastiaansen, A.J.N.M., Sparwasser, T., Smits, H.H., Hamming, J.F., Quax, P.H.A.

“…Recently, it was demonstrated that arteriogenesis is enhanced in mice deficient in regulatory T cells (CD4+CD25+FoxP3+ T cell), which can suppress effector T…”
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Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Disease by van der Bogt, Koen E.A., MD, PhD, Hellingman, Alwine A., MD, PhD, Lijkwan, Maarten A., MD, Bos, Ernst-Jan, MD, de Vries, Margreet R., BSc, van Rappard, Juliaan R.M., MS, Fischbein, Michael P., MD, Quax, Paul H., PhD, Robbins, Robert C., MD, Hamming, Jaap F., MD, PhD, Wu, Joseph C., MD, PhD

“…Objectives This study aims to provide insight into cellular kinetics using molecular imaging after different transplantation methods of bone marrow–derived…”
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Fibroblast growth factor receptors in in vitro and in vivo chondrogenesis: relating tissue engineering using adult mesenchymal stem cells to embryonic development by Hellingman, Catharine A, Koevoet, Wendy, Kops, Nicole, Farrell, Eric, Jahr, Holger, Liu, Wei, Baatenburg de Jong, Robert J, Frenz, Dorothy A, van Osch, Gerjo J V M

“…Adult mesenchymal stem cells (MSCs) are considered promising candidate cells for therapeutic cartilage and bone regeneration. Because tissue regeneration and…”
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T-cell-pre-stimulated Monocytes Promote Neovascularisation in a Murine Hind Limb Ischaemia Model by Hellingman, A.A, Zwaginga, J.J, van Beem, R.T, Hamming, J.F, Fibbe, W.E, Quax, P.H.A, Geutskens, S.B

“…Abstract Aim Monocytes play a significant role in neovascularisation. The stimuli that differentiate monocytes along a pro-angio-/arteriogenic-supporting…”
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Efficacy and efficiency of a streamlined multidisciplinary foot ulcer service by Hellingman, A.A., Smeets, H.J.

“…The structure of a multidisciplinary foot care service was modified to ensure that patient consultations were only attended by the relevant team members. This…”
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Canal wall up surgery with mastoid and epitympanic obliteration in acquired cholesteatoma by Hellingman, Catharine A., Geerse, Simon, de Wolf, Maarten J. F., Ebbens, Fenna A., van Spronsen, Erik

“…Objectives/Hypothesis The objective of this study was to evaluate surgical outcome and residual and recurrence rates of canal wall up (CWU) surgery with…”
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Management of a Nasal Spindle Cell Lipoma: Diagnostic and Therapeutic Considerations by Hellingman, Catharine A, Datema, Frank R

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FGF, TGFβ and Wnt crosstalk: embryonic to in vitro cartilage development from mesenchymal stem cells by Cleary, Mairéad A., van Osch, Gerjo J. V. M, Brama, Pieter A., Hellingman, Catharine A., Narcisi, Roberto

“…Articular cartilage is easily damaged, yet difficult to repair. Cartilage tissue engineering seems a promising therapeutic solution to restore articular…”
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Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia by Lijkwan, Maarten A, Hellingman, Alwine A, Bos, Ernst J, van der Bogt, Koen E A, Huang, Mei, Kooreman, Nigel G, de Vries, Margreet R, Peters, Hendrika A B, Robbins, Robert C, Hamming, Jaap F, Quax, Paul H A, Wu, Joseph C

“…In this study, we target the hypoxia inducible factor-1 alpha (HIF-1-alpha) pathway by short hairpin RNA interference therapy targeting prolyl hydroxylase-2…”
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Can one generate stable hyaline cartilage from adult mesenchymal stem cells? A developmental approach by Hellingman, Catharine A., Koevoet, Wendy, van Osch, Gerjo J. V. M.

“…Chondrogenically differentiating bone marrow‐derived mesenchymal stem cells (BMSCs) display signs of chondrocyte hypertrophy, such as production of collagen…”
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