Search Results - "Hellinger, Éva"

Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models by Hellinger, Éva, Veszelka, Szilvia, Tóth, Andrea E., Walter, Fruzsina, Kittel, Ágnes, Bakk, Mónika Laura, Tihanyi, Károly, Háda, Viktor, Nakagawa, Shinsuke, Dinh Ha Duy, Thuy, Niwa, Masami, Deli, Mária A., Vastag, Monika

“…Functional and morphological comparison of the primary endothelial triple co-culture blood–brain barrier (BBB) model, the high P-glycoprotein expressing…”
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Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport by Veszelka, Szilvia, Tóth, András, Walter, Fruzsina R, Tóth, Andrea E, Gróf, Ilona, Mészáros, Mária, Bocsik, Alexandra, Hellinger, Éva, Vastag, Monika, Rákhely, Gábor, Deli, Mária A

“…Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. Cell sources for BBB models include primary brain…”
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Sucrose esters increase drug penetration, but do not inhibit p-glycoprotein in caco-2 intestinal epithelial cells by Kiss, Lóránd, Hellinger, Éva, Pilbat, Ana-Maria, Kittel, Ágnes, Török, Zsolt, Füredi, András, Szakács, Gergely, Veszelka, Szilvia, Sipos, Péter, Ózsvári, Béla, Puskás, László G, Vastag, Monika, Szabó-Révész, Piroska, Deli, Mária A

“…Sucrose fatty acid esters are increasingly used as excipients in pharmaceutical products, but few data are available on their toxicity profile, mode of action,…”
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Drug penetration model of vinblastine-treated Caco-2 cultures by Hellinger, Éva, Bakk, Mónika Laura, Pócza, Péter, Tihanyi, Károly, Vastag, Monika

“…The penetrability of new chemical entities (NCE) is routinely screened in preclinical drug research. Although Caco-2 is a well-established model for human…”
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Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit by Veszelka, Szilvia, Tóth, Andrea E, Walter, Fruzsina R, Datki, Zsolt, Mózes, Emese, Fülöp, Lívia, Bozsó, Zsolt, Hellinger, Eva, Vastag, Monika, Orsolits, Barbara, Környei, Zsuzsanna, Penke, Botond, Deli, Mária A

“…Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β peptides (Aβ) as perivascular deposits and senile plaques in the brain. The intake…”
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The influence of 5-HT2A activity on a 5-HT2C specific in vivo assay used for early identification of multiple acting SERT and 5-HT2C receptor ligands by Éliás, Olivér, Nógrádi, Katalin, Domány, György, Szakács, Zoltán, Kóti, János, Szántay, Csaba, Tarcsay, Ákos, Keserű, György M., Gere, Anikó, Kiss, Béla, Kurkó, Dalma, Kolok, Sándor, Némethy, Zsolt, Kapui, Zoltán, Hellinger, Éva, Vastag, Mónika, Sághy, Katalin, Kedves, Rita, Gyertyán, István

“…[Display omitted] As a result of our exploratory programme aimed at elaborating dually acting compounds towards the serotonin (5-HT) transporter (SERT) and the…”
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Design of novel multiple-acting ligands towards SERT and 5-HT2C receptors by Éliás, Olivér, Ágai-Csongor, Éva, Domány, György, Keserű, György Miklós, Gere, Anikó, Kiss, Béla, Hellinger, Éva, Vastag, Mónika, Gyertyán, István

“…This Letter describes our attempts to elaborate dually acting compounds possessing serotonin re-uptake transporter inhibitor and serotonin 5-HT2C receptor…”
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Cell-based models of blood-brain barrier penetration by Vastag, Monika, Hellinger, Eva, Bakk, Mónika L, Tihanyi, Károly

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The influence of 5-HT 2A activity on a 5-HT 2C specific in vivo assay used for early identification of multiple acting SERT and 5-HT 2C receptor ligands by Éliás, Olivér, Nógrádi, Katalin, Domány, György, Szakács, Zoltán, Kóti, János, Szántay, Csaba, Tarcsay, Ákos, Keserű, György M., Gere, Anikó, Kiss, Béla, Kurkó, Dalma, Kolok, Sándor, Némethy, Zsolt, Kapui, Zoltán, Hellinger, Éva, Vastag, Mónika, Sághy, Katalin, Kedves, Rita, Gyertyán, István

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Histamine H4 receptor expression is elevated in human nasal polyp tissue by Jókúti, Adrienn, Hellinger, Éva, Hellinger, Andrea, Darvas, Zsuzsa, Falus, András, Thurmond, Robin L., Hirschberg, Andor

“…Altered histamine metabolism is thought to be involved in the pathomechanism of nasal polyposis characterized by local eosinophil infiltration. The present…”
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The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands by Éliás, Olivér, Nógrádi, Katalin, Domány, György, Szakács, Zoltán, Kóti, János, Szántay, Jr, Csaba, Tarcsay, Ákos, Keserű, György M, Gere, Anikó, Kiss, Béla, Kurkó, Dalma, Kolok, Sándor, Némethy, Zsolt, Kapui, Zoltán, Hellinger, Éva, Vastag, Mónika, Sághy, Katalin, Kedves, Rita, Gyertyán, István

“…As a result of our exploratory programme aimed at elaborating dually acting compounds towards the serotonin (5-HT) transporter (SERT) and the 5-HT2C receptor a…”
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Design of novel multiple-acting ligands towards SERT and 5-HT sub(2C) receptors by Elias, Oliver, Agai-Csongor, Eva, Domany, Gyorgy, Keserue, Gyorgy Miklos, Gere, Aniko, Kiss, Bela, Hellinger, Eva, Vastag, Monika, Gyertyan, Istvan

“…This Letter describes our attempts to elaborate dually acting compounds possessing serotonin re-uptake transporter inhibitor and serotonin 5-HT sub(2C)…”
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The influence of 5-HT sub(2A) activity on a 5-HT sub(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT sub(2C) receptor ligands by Elias, Oliver, Nogradi, Katalin, Domany, Gyorgy, Szakacs, Zoltan, Koti, Janos, Szantay, Csaba Jr, Tarcsay, Akos, Keserue, Gyorgy M, Gere, Aniko, Kiss, Bela, Kurko, Dalma, Kolok, Sandor, Nemethy, Zsolt, Kapui, Zoltan, Hellinger, Eva, Vastag, Monika, Saghy, Katalin, Kedves, Rita, Gyertyan, Istvan

“…As a result of our exploratory programme aimed at elaborating dually acting compounds towards the serotonin (5-HT) transporter (SERT) and the 5-HT sub(2C)…”
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