Search Results - "Hellewell, Sarah C."

Blast-Induced Neurotrauma Results in Spatially Distinct Gray Matter Alteration Alongside Hormonal Alteration: A Preliminary Investigation by Hellewell, Sarah C, Granger, Douglas A, Cernak, Ibolja

“…Blast-induced neurotrauma (BINT) frequently occurs during military training and deployment and has been linked to long-term neuropsychological and…”
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Cuprizone feed formulation influences the extent of demyelinating disease pathology by Toomey, Lillian M., Papini, Melissa, Lins, Brittney, Wright, Alexander J., Warnock, Andrew, McGonigle, Terence, Hellewell, Sarah C., Bartlett, Carole A., Anyaegbu, Chidozie, Fitzgerald, Melinda

“…Cuprizone is a copper-chelating agent that induces pathology similar to that within some multiple sclerosis (MS) lesions. The reliability and reproducibility…”
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Editorial: Stress in health and disease: new era and new challenges by Uchakin, Peter N., Hellewell, Sarah C., Stowe, Raymond P.

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Characterizing the Risk of Depression Following Mild Traumatic Brain Injury: A Meta-Analysis of the Literature Comparing Chronic mTBI to Non-mTBI Populations by Hellewell, Sarah C., Beaton, Caerwen S., Welton, Thomas, Grieve, Stuart M.

“…Objective: Mild traumatic brain injury (mTBI) is associated with depressed mood acutely post-injury, but there is little evidence regarding long-term…”
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NK1 antagonists attenuate tau phosphorylation after blast and repeated concussive injury by Corrigan, Frances, Cernak, Ibolja, McAteer, Kelly, Hellewell, Sarah C., Rosenfeld, Jeffrey V., Turner, Renée J., Vink, Robert

“…Exposure to repeated concussive traumatic brain injury (TBI) and to blast-induced TBI has been associated with the potential development of the…”
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Secondary Degeneration Impairs Myelin Ultrastructural Development in Adulthood following Adolescent Neurotrauma in the Rat Optic Nerve by Lins, Brittney R, Anyaegbu, Chidozie C, McGonigle, Terence, Hellewell, Sarah C, Patel, Parth, Reagan, Harry, Rooke-Wiesner, Cara, Warnock, Andrew, Archer, Michael, Hemmi, Jan M, Bartlett, Carole, Fitzgerald, Melinda

“…Adolescence is a critical period of postnatal development characterized by social, emotional, and cognitive changes. These changes are increasingly understood…”
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Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic compounds by Lins, Brittney R, Anyaegbu, Chidozie C, Hellewell, Sarah C, Papini, Melissa, McGonigle, Terence, De Prato, Luca, Shales, Matthew, Fitzgerald, Melinda

“…Traumatic brain injury is common, and often results in debilitating consequences. Even mild traumatic brain injury leaves approximately 20% of patients with…”
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Diffusion kurtosis imaging detects subclinical white matter abnormalities in Phenylketonuria by Hellewell, Sarah C., Welton, Thomas, Eisenhuth, Kate, Tchan, Michel C., Grieve, Stuart M.

“…•Diffusion and diffusion kurtosis MRI metrics were examined in adults with PKU.•A candidate metric (Krad/KFA) delineated diet-compliant and non-compliant…”
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Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury by Yan, Edwin B, Hellewell, Sarah C, Bellander, Bo-Michael, Agyapomaa, Doreen A, Morganti-Kossmann, M Cristina

“…The combination of diffuse brain injury with a hypoxic insult is associated with poor outcomes in patients with traumatic brain injury. In this study, we…”
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Characteristic patterns of white matter tract injury in sport-related concussion: An image based meta-analysis by Hellewell, Sarah C., Nguyen, Vy P.B., Jayasena, Ruchira N., Welton, Thomas, Grieve, Stuart M.

“…•This image-based meta-analysis compiled the raw fractional anisotropy data from studies using tract-based spatial statistics to determine regions susceptible…”
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The Australian Traumatic Brain Injury Initiative: Statement of Working Principles and Rapid Review of Methods to Define Data Dictionaries for Neurological Conditions by Bagg, Matthew K, Hicks, Amelia J, Hellewell, Sarah C, Ponsford, Jennie L, Lannin, Natasha A, O'Brien, Terence J, Cameron, Peter A, Cooper, D Jamie, Rushworth, Nick, Gabbe, Belinda J, Fitzgerald, Melinda

“…The Australian Traumatic Brain Injury Initiative (AUS-TBI) aims to develop a health informatics approach to collect data predictive of outcomes for persons…”
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Plasma Lipid Profiles Change with Increasing Numbers of Mild Traumatic Brain Injuries in Rats by Anyaegbu, Chidozie C, Szemray, Harrison, Hellewell, Sarah C, Lawler, Nathan G, Leggett, Kerry, Bartlett, Carole, Lins, Brittney, McGonigle, Terence, Papini, Melissa, Anderton, Ryan S, Whiley, Luke, Fitzgerald, Melinda

“…Mild traumatic brain injury (mTBI) causes structural, cellular and biochemical alterations which are difficult to detect in the brain and may persist…”
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The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments by Morganti-Kossmann, Maria Cristina, Semple, Bridgette D., Hellewell, Sarah C., Bye, Nicole, Ziebell, Jenna M.

“…This review recounts the definitions and research evidence supporting the multifaceted roles of neuroinflammation in the injured brain following trauma. We…”
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Measuring Resilience to Operational Stress in Canadian Armed Forces Personnel by Hellewell, Sarah C., Cernak, Ibolja

“…Adaptability to stress is governed by innate resilience, comprised of complex neuroendocrine and immune mechanisms alongside inherited or learned behavioral…”
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Traumatic Brain Injury within Domestic Relationships: Complications, Consequences and Contributing Factors by Baxter, Kathleen, Hellewell, Sarah C.

“…Traumatic brain injury (TBI) resulting from episodes of domestic violence (DV) is a serious yet greatly underreported issue. Head injuries arising in these…”
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Post-traumatic hypoxia exacerbates brain tissue damage: analysis of axonal injury and glial responses by Hellewell, Sarah C, Yan, Edwin B, Agyapomaa, Doreen A, Bye, Nicole, Morganti-Kossmann, M Cristina

“…Traumatic brain injury (TBI) resulting in poor neurological outcome is predominantly associated with diffuse brain damage and secondary hypoxic insults…”
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Investigating the Link between Later-Life Brain Volume and Cardiorespiratory Fitness after Mild Traumatic Brain Injury Exposure by Markovic, Shaun J, Hellewell, Sarah C, Doré, Vincent, Xia, Ying, Scott, Brendan R, Peiffer, Jeremiah J, Fitzgerald, Melinda, Brown, Belinda M

“…Evidence suggests that maintaining a higher level of cardiorespiratory fitness (CRF) later in life can offer some protection against brain volume loss as we…”
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Symptoms Associated With Exercise Intolerance and Resting Heart Rate Following Mild Traumatic Brain Injury by Thorne, Jacinta, Hellewell, Sarah C, Cowen, Gill, Ring, Alexander, Jefferson, Amanda, Chih, HuiJun, Gozt, Aleksandra K, Buhagiar, Francesca, Thomas, Elizabeth, Papini, Melissa, Bynevelt, Michael, Celenza, Antonio, Xu, Dan, Honeybul, Stephen, Pestell, Carmela F, Fatovich, Daniel, Fitzgerald, Melinda

“…People may experience a myriad of symptoms after mild traumatic brain injury (mTBI), but the relationship between symptoms and objective assessments is poorly…”
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Erythropoietin Does Not Alter Serum Profiles of Neuronal and Axonal Biomarkers After Traumatic Brain Injury: Findings From the Australian EPO-TBI Clinical Trial by Hellewell, Sarah C., Mondello, Stefania, Conquest, Alison, Shaw, Gerry, Madorsky, Irina, Deng, Jay V., Little, Lorraine, Kobeissy, Firas, Bye, Nicole, Bellomo, Rinaldo, Cooper, David J., Vallance, Shirley, Board, Jasmine, Morganti-Kossmann, Maria C.

“…OBJECTIVE:To determine profiles of serum ubiquitin carboxy-terminal hydrolase L1 and phosphorylated neurofilament heavy-chain, examine whether erythropoietin…”
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Diffusion MRI as a complementary assessment to cognition, emotion, and motor dysfunction after sports-related concussion: a systematic review and critical appraisal of the literature by Hellewell, Sarah C., Welton, Thomas, Pearce, Alan J., Maller, Jerome J., Grieve, Stuart M.

“…Sports-related concussion (SRC) is a complex and heterogeneous injury with psychological, cognitive and functional consequences. Advances in diffusion magnetic…”
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