Search Results - "Hellevik, Leif R."

Examining temporal changes in model-optimized parameters using longitudinal hemodynamic measurements by Bjørdalsbakke, Nikolai L, Sturdy, Jacob, Wisløff, Ulrik, Hellevik, Leif R

“…We previously applied hemodynamic data to personalize a mathematical model of the circulation expressed as physically interpretable parameters. The aim of this…”
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Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements by Bjørdalsbakke, Nikolai L, Sturdy, Jacob, Ingeström, Emma M L, Hellevik, Leif R

“…Physics-based cardiovascular models are only recently being considered for disease diagnosis or prognosis in clinical settings. These models depend on…”
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Bond Graph Model of Cerebral Circulation: Toward Clinically Feasible Systemic Blood Flow Simulations by Safaei, Soroush, Blanco, Pablo J, Müller, Lucas O, Hellevik, Leif R, Hunter, Peter J

“…We propose a detailed CellML model of the human cerebral circulation that runs faster than real time on a desktop computer and is designed for use in clinical…”
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Machine learning augmented reduced-order models for FFR-prediction by Fossan, Fredrik E., Müller, Lucas O., Sturdy, Jacob, Bråten, Anders T., Jørgensen, Arve, Wiseth, Rune, Hellevik, Leif R.

“…Computational predictions in cardiovascular medicine have largely relied on explicit models derived from physical and physiological principles. Recently, the…”
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Optimization of topological complexity for one-dimensional arterial blood flow models by Fossan, Fredrik E, Mariscal-Harana, Jorge, Alastruey, Jordi, Hellevik, Leif R

“…As computational models of the cardiovascular system are applied in modern personalized medicine, maximizing certainty of model input becomes crucial. A model…”
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Impact of baseline coronary flow and its distribution on fractional flow reserve prediction by Müller, Lucas O., Fossan, Fredrik E., Bråten, Anders T., Jørgensen, Arve, Wiseth, Rune, Hellevik, Leif R.

“…Model‐based prediction of fractional flow reserve (FFR) in the context of stable coronary artery disease (CAD) diagnosis requires a number of modelling…”
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Parameter estimation for closed-loop lumped parameter models of the systemic circulation using synthetic data by Bjørdalsbakke, Nikolai L., Sturdy, Jacob T., Hose, David R., Hellevik, Leif R.

“…Physics-based models can be applied to describe mechanisms in both health and disease, which has the potential to accelerate the development of personalized…”
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Uncertainty Quantification and Sensitivity Analysis for Computational FFR Estimation in Stable Coronary Artery Disease by Fossan, Fredrik E., Sturdy, Jacob, Müller, Lucas O., Strand, Andreas, Bråten, Anders T., Jørgensen, Arve, Wiseth, Rune, Hellevik, Leif R.

“…Purpose The main objectives of this study are to validate a reduced-order model for the estimation of the fractional flow reserve (FFR) index based on blood…”
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Roadmap for cardiovascular circulation model by Safaei, Soroush, Bradley, Christopher P., Suresh, Vinod, Mithraratne, Kumar, Muller, Alexandre, Ho, Harvey, Ladd, David, Hellevik, Leif R., Omholt, Stig W., Chase, J. Geoffrey, Müller, Lucas O., Watanabe, Sansuke M., Blanco, Pablo J., Bono, Bernard, Hunter, Peter J.

“…Computational models of many aspects of the mammalian cardiovascular circulation have been developed. Indeed, along with orthopaedics, this area of physiology…”
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Velocity profiles in the human ductus venosus: a numerical fluid structure interaction study by Leinan, Paul R., Degroote, Joris, Kiserud, Torvid, Skallerud, Bjørn, Vierendeels, Jan, Hellevik, Leif R.

“…The veins distributing oxygenated blood from the placenta to the fetal body have been given much attention in clinical Doppler velocimetry studies, in…”
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Human Ductus Venosus Velocity Profiles in the First Trimester by Leinan, Paul R., Kiserud, Torvid, Hellevik, Leif R.

“…The fluid dynamics in the human fetal ductus venosus in the early stage of pregnancy is not well explored. Consequently, there is an uncertainty in the…”
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Uncertainty quantification of computational coronary stenosis assessment and model based mitigation of image resolution limitations by Sturdy, Jacob, Kjernlie, Johannes Kløve, Nydal, Hallvard Moian, Eck, Vinzenz G., Hellevik, Leif R.

“…•The effects of clinically relevant uncertainties on the prediction of FFR are quantified.•The effects of limitations in medical imaging are assessed and a new…”
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Automated computed tomography-derived fractional flow reserve model for diagnosing haemodynamically significant coronary artery disease: a prospective validation study by Bråten, Anders T, Fossan, Fredrik E, Muller, Lucas O, Jørgensen, Arve, Stensæth, Knut H, Hellevik, Leif R, Wiseth, Rune

“…This study aims to assess the diagnostic performance of a novel computed tomography-derived fractional flow reserve (CT-FFR) algorithm and to compare its…”
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Ultrasonographic velocimetry of the fetal ductus venosus by Kiserud, T, Eik-Nes, S H, Blaas, H G, Hellevik, L R

“…In fetal lambs, the ductus venosus shunts well-oxygenated blood directly to the heart, a pattern expected to be found also in the human fetus. We aimed to…”
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