Search Results - "Heller, N M"

Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming by D'Alessio, F R, Craig, J M, Singer, B D, Files, D C, Mock, J R, Garibaldi, B T, Fallica, J, Tripathi, A, Mandke, P, Gans, J H, Limjunyawong, N, Sidhaye, V K, Heller, N M, Mitzner, W, King, L S, Aggarwal, N R

“…Despite intense investigation, acute respiratory distress syndrome (ARDS) remains an enormous clinical problem for which no specific therapies currently exist…”
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The role of post-transcriptional regulation in chemokine gene expression in inflammation and allergy by Fan, J, Heller, N. M, Gorospe, M, Atasoy, U, Stellato, C

“…The aim of this review is to discuss recent advances in the understanding of the regulation of chemokine expression occurring during chronic inflammatory…”
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Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro by Gao, P S, Heller, N M, Walker, W, Chen, C H, Moller, M, Plunkett, B, Roberts, M H, Schleimer, R P, Hopkin, J M, Huang, S K

“…Because of their close proximity to the transcription start site, we first conducted a case-control association analysis of the GT repeat variants and atopic…”
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Assessment of signal transducer and activator of transcription 6 as a target of glucocorticoid action in human airway epithelial cells by Heller, N. M., Matsukura, S., Georas, S. N., Boothby, M. R., Stellato, C., Schleimer, R. P.

“…Summary Background Activation of signal transducer and activator of transcription (STAT)6 by IL‐4 and IL‐13 is essential in many key epithelial responses in…”
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Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System by LaPorte, Sherry L., Juo, Z. Sean, Vaclavikova, Jana, Colf, Leremy A., Qi, Xiulan, Heller, Nicola M., Keegan, Achsah D., Garcia, K. Christopher

“…Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which are associated with allergy and…”
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Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial by Margolin, Kim, Prof, Ernstoff, Marc S, MD, Hamid, Omid, MD, Lawrence, Donald, MD, McDermott, David, MD, Puzanov, Igor, MD, Wolchok, Jedd D, MD, Clark, Joseph I, Prof, Sznol, Mario, MD, Logan, Theodore F, MD, Richards, Jon, MD, Michener, Tracy, PharmD, Balogh, Agnes, MS, Heller, Kevin N, MD, Hodi, F Stephen, MD

“…Summary Background Brain metastases commonly develop in patients with melanoma and are a frequent cause of death of patients with this disease. Ipilimumab…”
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Photosensitive properties of metal-containing polydisalicylidene azomethines by Alexandrova, E. L., Ivanov, A. G., Heller, N. M., Nadezhdina, L. B., Shamanin, V. V.

“…Photosensitive properties of new metal-containing polydisalicylidene azomethines were studied. It was shown that polymer properties are controlled by the…”
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Polydisalicylidene azomethyne/Si(GaAs) heterojunctions: Development and properties by Nikolaev, Yu. A., Rud’, V. Yu, Rud’, Yu. V., Terukov, E. I., Heller, N. M., Ivanov, A. G., Shamanin, V. V.

“…An athermal nonvacuum technology was suggested and implemented, and nonclassically polyconjugated polydisalicylidene azomethyne/Si(GaAs) heterojunctions were…”
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Interferon-gamma inhibits STAT6 signal transduction and gene expression in human airway epithelial cells by Heller, Nicola M, Matsukura, Satoshi, Georas, Steve N, Boothby, Mark R, Rothman, Paul B, Stellato, Cristiana, Schleimer, Robert P

“…The activating and inhibitory cytokine signals that act upon epithelial cells in the human lung are critically important for controlling the production of…”
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The Type I Il-4 Receptor Complex Selectively Activates The Tyrosine Phosphorylation Of IRS-2 by Heller, N.M, Qi, X, Junttila, I, Paul, W.E, Keegan, A.D

“…[...]there are reports of differential responses to these cytokines in vitro and in vivo. [...]we compared signaling between these cytokines…”
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American Board of Emergency Medicine Report on Residency Training Information (2014-2015) by Smith-Coggins, Rebecca, MD, Marco, Catherine A., MD, Baren, Jill M., MD, Beeson, Michael S., MD, Carius, Michael L., MD, Counselman, Francis L., MD, Heller, Barry N., MD, Kowalenko, Terry, MD, Muelleman, Robert L., MD, Nelson, Lewis S., MD, Wahl, Robert P., MD, Korte, Robert C., PhD, Joldersma, Kevin B., PhD

“…The American Board of Emergency Medicine (ABEM) gathers extensive background information on emergency medicine residency programs and the residents in those…”
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Expression of the Costimulatory Molecule B7-H2 (Inducible Costimulator Ligand) by Human Airway Epithelial Cells by Kurosawa, Shin, Myers, Allen C, Chen, Lieping, Wang, Shengdian, Ni, Jian, Plitt, James R, Heller, Nicola M, Bochner, Bruce S, Schleimer, Robert P

“…Tissue structural cells are known in some situations to play a role in the presentation of antigen and in immunoregulation. We assessed the expression of B7…”
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Regulation of STAT6 by interferon- (IFN-) [gamma] in human airway epithelial cells by Heller, NM, Matsukura, S, Georas, SN, Boothby, M, Stellato, C, Schleimer, RP

“…It is known that the Th1-type cytokine IFN-γ can antagonize respiratory epithelial responses to antigen or IL-4. Therefore, we investigated the effect of IFN-γ…”
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Detection and quantitation of fatty acid acyl conjugates of triamcinolone acetonide via gas chromatography–electron-capture negative-ion mass spectrometry by Hubbard, Walter C, Blum, Andrew E, Bickel, Carol A, Heller, Nicola M, Schleimer, Robert P

“…The inherent electron-capture properties of triamcinolone acetonide (TAA) fatty acid conjugates were exploited for development of a GC–MS technique for…”
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Dinucleotide (GT) repeat variants in the first exon of the STAT6 gene differentially regulate the promoter activity in vitro by Gao, P.S., Heller, N.M., Plunkett, B., Schleimer, R.P., Huang, S.K.

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Detection and quantitation of C16 and C18 fatty acid acyl conjugates of triamcinolone acetonide (TAA) in airway epithelial cells using gas chromatography-mass spectrometry by Schleimer, R.P., Blum, A.E., Bickel, C.A., Heller, N.M., Hubbard, W.C.

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Airway epithelial cell activation and toll-like receptors (TLR) by Sha, Q., Plitt, J.R., Heller, N.M., Beck, L.A., Imani, F., Schleimer, R.P.

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