Search Results - "Heller, Jir̆í"
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The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import
Published in Current biology (05-11-2018)“…The mitochondrial contact site and cristae organization system (MICOS) is a multiprotein complex responsible for cristae formation. Even though cristae are…”
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The essential cysteines in the CIPC motif of the thioredoxin-like Trypanosoma brucei MICOS subunit TbMic20 do not form an intramolecular disulfide bridge in vivo
Published in Molecular and biochemical parasitology (01-03-2022)“…The mitochondrial protein import machinery of trypanosomatids is highly divergent from that of the well-studied models such as baker’s yeast. A notable example…”
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Angiotensin II–Induced Hypertension in Bradykinin B2 Receptor Knockout Mice
Published in Hypertension (Dallas, Tex. 1979) (01-03-2001)“…The present study was performed to examine the role of endogenous bradykinin (BK) in the development of angiotensin II (Ang II)–induced hypertension in mice…”
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Journal Article Conference Proceeding -
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Role of nNOS in Regulation of Renal Function in Angiotensin II—Induced Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-08-2001)“…ABSTRACT—Previous studies have indicated that in normotensive rats, NO produced by neuronal NO synthase (nNOS) plays an important role in modulating…”
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Intrarenal infusion of angiotensin-(1-7) modulates renal functional responses to exogenous angiotensin II in the rat
Published in Kidney & blood pressure research (01-01-2002)“…In the present study we investigated the possible role of angiotensin-(1-7) [Ang-(1-7)] in modulating renal functional responses to intrarenal (i.e.) infusion…”
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Angiotensin II–Induced Hypertension in Bradykinin B 2 Receptor Knockout Mice
Published in Hypertension (Dallas, Tex. 1979) (01-03-2001)“…The present study was performed to examine the role of endogenous bradykinin (BK) in the development of angiotensin II (Ang II)–induced hypertension in mice…”
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Long-term effect on blood pressure of early brief treatment by different antihypertensive agents: a study in the prague hypertensive rat
Published in Kidney & blood pressure research (01-01-1998)“…In the Prague hypertensive rat (PHR), a strain of genetic hypertension derived from Wistar, administration of various antihypertensive drugs (AHD) during the…”
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The role of the kidney in the development of hypertension : a transplantation study in the Prague hypertensive rat
Published in Pflügers Archiv (01-11-1993)“…It has been shown that genetic hypertension in rats usually "travels with the kidney". To elucidate the mechanism of this phenomenon further, experiments were…”
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Possible contribution of impaired sodium excretion to the development and maintenance of hypertension: a study of the isolated kidneys of the Prague hypertensive rat
Published in Pflügers Archiv (01-09-1997)“…We have shown previously that in the Prague Hypertensive Rat (PHR) "hypertension travels with the kidney" and that the kidney appears to produce an as yet…”
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The effect of two different calcium antagonists on the glomerular haemodynamics in the dog
Published in Pflügers Archiv (01-03-1990)“…Kidney function of beagles fed a constant amount of food containing 3 mmol sodium.kgbodywt-1.day-1, and anaesthetized with pentobarbitone was investigated by…”
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Effect of PD 123319, an AT-2 antagonist, on renal function of the anesthetized dog: comparison with EXP 3174, an AT-1 blocker
Published in Kidney & blood pressure research (01-01-1997)“…In anaesthetized dogs fed a diet delivering 3.5 mmol NaCl/kg/day, PD 123319 - an angiotensin (AT) II (Ang II) antagonist preferentially bound to AT-2 receptors…”
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P-325: Enhanced JNK2 activity in the hypertrophic heart ventricle of Prague-Hypertensive Rat (PHR) is independent of circulating or tissue endothelin (ET)
Published in American journal of hypertension (01-04-2002)“…Since MAP kinases may be involved in cardiac hypertrophy in spontaneously hypertensive rats and their activation may be due to stimulation by ET, we studied…”
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Relative roles of nitric oxide, prostanoids and angiotensin II in the regulation of canine glomerular hemodynamics. A micropuncture study
Published in Kidney & blood pressure research (2004)“…Glomerular hemodynamics are controlled by a variety of physical, nervous and hormonal factors including the potent vasoconstrictors, angiotensin (ANG) II and…”
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Effect of intrarenal infusion of angiotensin-(1-7) in the dog
Published in Kidney & blood pressure research (01-01-2000)“…Angiotensin-(1-7), (Ang-(1-7)), a metabolite of Ang II and /or Ang I, was infused into the renal artery (i.r.a) of anesthetized dogs in order to demonstrate…”
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The renal endothelin system in the Prague hypertensive rat, a new model of spontaneous hypertension
Published in Clinical science (1979) (01-07-1999)“…In a new model of spontaneous hypertension, namely the Prague hypertensive rat (PHR), hypertension is transferred with a kidney transplanted from the PHR to…”
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Action of endothelin-1 on glomerular haemodynamics in the dog: lack of direct effects on glomerular ultrafiltration coefficient
Published in Clinical science (1979) (01-05-1996)“…1. Although numerous studies have demonstrated the potent vasoconstrictor effect of endothelin-1 on the renal vasculature, it is difficult to differentiate in…”
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Cardiac hypertrophy in the Prague-hypertensive rat is associated with enhanced JNK2 but not ERK tissue activity
Published in Kidney & blood pressure research (01-01-2001)“…Mitogen-activated protein (MAP) kinases are important intracellular mediators for proliferation and hypertrophy and therefore may also regulate cardiomyoblast…”
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The effect of kinin and prostaglandin inhibitors on the renal response to angiotensin-converting enzyme inhibition : a micropuncture study in the dog
Published in Pflügers Archiv (01-06-1994)“…It has been suggested that angiotensin-converting enzyme (ACE) inhibition is accompanied by enhanced bradykinin and prostaglandin activities, which may…”
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Conference Proceeding Journal Article -
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Effect of a converting enzyme inhibitor, angiotensin II, and saralasin on glomerular hemodynamics
Published in Kidney international. Supplement (01-11-1990)Get more information
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