Search Results - "Hell, W"

CaMKII: claiming center stage in postsynaptic function and organization by Hell, Johannes W

“…While CaMKII has long been known to be essential for synaptic plasticity and learning, recent work points to new dimensions of CaMKII function in the nervous…”
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Far-Field Optical Nanoscopy by Hell, Stefan W

“…In 1873, Ernst Abbe discovered what was to become a well-known paradigm: the inability of a lens-based optical microscope to discern details that are closer…”
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Room temperature high-fidelity holonomic single-qubit gate on a solid-state spin by Arroyo-Camejo, Silvia, Lazariev, Andrii, Hell, Stefan W., Balasubramanian, Gopalakrishnan

“…At its most fundamental level, circuit-based quantum computation relies on the application of controlled phase shift operations on quantum registers. While…”
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STED Nanoscopy Reveals the Ubiquity of Subcortical Cytoskeleton Periodicity in Living Neurons by D’Este, Elisa, Kamin, Dirk, Göttfert, Fabian, El-Hady, Ahmed, Hell, Stefan W.

“…In the axons of cultured hippocampal neurons, actin forms various structures, including bundles, patches (involved in the preservation of neuronal polarity),…”
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MINFLUX nanometer-scale 3D imaging and microsecond-range tracking on a common fluorescence microscope by Schmidt, Roman, Weihs, Tobias, Wurm, Christian A., Jansen, Isabelle, Rehman, Jasmin, Sahl, Steffen J., Hell, Stefan W.

“…The recently introduced minimal photon fluxes (MINFLUX) concept pushed the resolution of fluorescence microscopy to molecular dimensions. Initial…”
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STED Nanoscopy of Actin Dynamics in Synapses Deep Inside Living Brain Slices by Urban, Nicolai T., Willig, Katrin I., Hell, Stefan W., Nägerl, U. Valentin

“…It is difficult to investigate the mechanisms that mediate long-term changes in synapse function because synapses are small and deeply embedded inside brain…”
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How Ca2+-permeable AMPA receptors, the kinase PKA, and the phosphatase PP2B are intertwined in synaptic LTP and LTD by Hell, Johannes W

“…Both synaptic long-term potentiation (LTP) and long-term depression (LTD) are thought to be critical for memory formation. Dell'Acqua and co-workers now…”
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Triarylmethane Fluorophores Resistant to Oxidative Photobluing by Butkevich, Alexey N, Bossi, Mariano L, Lukinavičius, Gražvydas, Hell, Stefan W

“…Spectral stability of small-molecule fluorescent probes is required for correct interpretation and reproducibility of multicolor fluorescence imaging data, in…”
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Distinct Eligibility Traces for LTP and LTD in Cortical Synapses by He, Kaiwen, Huertas, Marco, Hong, Su Z., Tie, XiaoXiu, Hell, Johannes W., Shouval, Harel, Kirkwood, Alfredo

“…In reward-based learning, synaptic modifications depend on a brief stimulus and a temporally delayed reward, which poses the question of how synaptic activity…”
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Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells by Honigmann, Alf, Mueller, Veronika, Ta, Haisen, Schoenle, Andreas, Sezgin, Erdinc, Hell, Stefan W., Eggeling, Christian

“…The interaction of lipids and proteins plays an important role in plasma membrane bioactivity, and much can be learned from their diffusion characteristics…”
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Reversibly Photoswitchable Fluorescent Diarylethenes Resistant against Photobleaching in Aqueous Solutions by Uno, Kakishi, Bossi, Mariano L, Irie, Masahiro, Belov, Vladimir N, Hell, Stefan W

“…Low photostability in aqueous solutions is the main drawback of synthetic photochromic dyes, which limits their switching performance and utility in biology,…”
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Ultrastructural anatomy of nodes of Ranvier in the peripheral nervous system as revealed by STED microscopy by D’Este, Elisa, Kamin, Dirk, Balzarotti, Francisco, Hell, Stefan W.

“…We used stimulated emission depletion (STED) superresolution microscopy to analyze the nanoscale organization of 12 glial and axonal proteins at the nodes of…”
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MINSTED fluorescence localization and nanoscopy by Weber, Michael, Leutenegger, Marcel, Stoldt, Stefan, Jakobs, Stefan, Mihaila, Tiberiu S., Butkevich, Alexey N., Hell, Stefan W.

“…We introduce MINSTED, a fluorophore localization and super-resolution microscopy concept based on stimulated emission depletion (STED) that provides spatial…”
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Toward fluorescence nanoscopy by Hell, Stefan W

“…For more than a century, the resolution of focusing light microscopy has been limited by diffraction to 180 nm in the focal plane and to 500 nm along the optic…”
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Adaptive-illumination STED nanoscopy by Heine, Jörn, Reuss, Matthias, Harke, Benjamin, D’Este, Elisa, Sahl, Steffen J., Hell, Stefan W.

“…The concepts called STED/RESOLFT superresolve features by a light-driven transfer of closely packed molecules between two different states, typically a…”
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Nanoscopy in a Living Mouse Brain by Berning, Sebastian, Willig, Katrin I., Steffens, Heinz, Dibaj, Payam, Hell, Stefan W.

“…We demonstrated superresolution optical microscopy in a living higher animal. Stimulated emission depletion (STED) fluorescence nanoscopy reveals neurons in…”
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SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy by Lukinavičius, Gražvydas, Blaukopf, Claudia, Pershagen, Elias, Schena, Alberto, Reymond, Luc, Derivery, Emmanuel, Gonzalez-Gaitan, Marcos, D’Este, Elisa, Hell, Stefan W., Wolfram Gerlich, Daniel, Johnsson, Kai

“…Cell-permeable DNA stains are popular markers in live-cell imaging. Currently used DNA stains for live-cell imaging are either toxic, require illumination with…”
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CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells by Ratz, Michael, Testa, Ilaria, Hell, Stefan W., Jakobs, Stefan

“…Overexpression is a notorious concern in conventional and especially in super-resolution fluorescence light microscopy studies because it may cause numerous…”
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MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation by Stephan, Till, Brüser, Christian, Deckers, Markus, Steyer, Anna M, Balzarotti, Francisco, Barbot, Mariam, Behr, Tiana S, Heim, Gudrun, Hübner, Wolfgang, Ilgen, Peter, Lange, Felix, Pacheu‐Grau, David, Pape, Jasmin K, Stoldt, Stefan, Huser, Thomas, Hell, Stefan W, Möbius, Wiebke, Rehling, Peter, Riedel, Dietmar, Jakobs, Stefan

“…Mitochondrial function is critically dependent on the folding of the mitochondrial inner membrane into cristae; indeed, numerous human diseases are associated…”
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Fluorogenic probes for live-cell imaging of the cytoskeleton by Lukinavičius, Gražvydas, Reymond, Luc, D'Este, Elisa, Masharina, Anastasiya, Göttfert, Fabian, Ta, Haisen, Güther, Angelika, Fournier, Mathias, Rizzo, Stefano, Waldmann, Herbert, Blaukopf, Claudia, Sommer, Christoph, Gerlich, Daniel W, Arndt, Hans-Dieter, Hell, Stefan W, Johnsson, Kai

“…Far-red fluorogenic probes for live-cell imaging of either actin or tubulin are described and used for super-resolution microscopy of various structures in a…”
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