Search Results - "Helio, T"

An In‐Depth Exploration of Six Decades of the Kröhnke Pyridine Synthesis by Francisco, Telmo N., Albuquerque, Hélio M. T., Silva, Artur M. S.

“…The Kröhnke Pyridine Synthesis has been discovered about six decades ago (1961), by Fritz Kröhnke and Wilfried Zecher at the University of Giessen. The…”
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Microwave Irradiation: Alternative Heating Process for the Synthesis of Biologically Applicable Chromones, Quinolones, and Their Precursors by Albuquerque, Hélio M T, Pinto, Diana C G A, Silva, Artur M S

“…Microwave irradiation has become a popular heating technique in organic synthesis, mainly due to its short reaction times, solventless reactions, and,…”
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Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases by Caforio, Alida L P, Pankuweit, Sabine, Arbustini, Eloisa, Basso, Cristina, Gimeno-Blanes, Juan, Felix, Stephan B, Fu, Michael, Heliö, Tiina, Heymans, Stephane, Jahns, Roland, Klingel, Karin, Linhart, Ales, Maisch, Bernhard, McKenna, William, Mogensen, Jens, Pinto, Yigal M, Ristic, Arsen, Schultheiss, Heinz-Peter, Seggewiss, Hubert, Tavazzi, Luigi, Thiene, Gaetano, Yilmaz, Ali, Charron, Philippe, Elliott, Perry M

“…In this position statement of the ESC Working Group on Myocardial and Pericardial Diseases an expert consensus group reviews the current knowledge on clinical…”
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A novel desmoplakin mutation causes dilated cardiomyopathy with palmoplantar keratoderma as an early clinical sign by Karvonen, V., Harjama, L., Heliö, K., Kettunen, K., Elomaa, O., Koskenvuo, J.W., Kere, J., Weckström, S., Holmström, M., Saarela, J., Ranki, A., Heliö, T., Hannula‐Jouppi, K.

“…Background PPKs represent a heterogeneous group of disorders with hyperkeratosis of palmar and/or plantar skin. PPK, hair shaft abnormalities, cardiomyopathy…”
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Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications by Albuquerque, Hélio M T, Santos, Clementina M M, Silva, Artur M S

“…This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These…”
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Diagnostic work-up in cardiomyopathies: bridging the gap between clinical phenotypes and final diagnosis. A position statement from the ESC Working Group on Myocardial and Pericardial Diseases by Rapezzi, Claudio, Arbustini, Eloisa, Caforio, Alida L P, Charron, Philippe, Gimeno-Blanes, Juan, Heliö, Tiina, Linhart, Ales, Mogensen, Jens, Pinto, Yigal, Ristic, Arsen, Seggewiss, Hubert, Sinagra, Gianfranco, Tavazzi, Luigi, Elliott, Perry M

“…In 2008, The ESC Working Group on Myocardial and Pericardial Diseases proposed an updated classification of cardiomyopathies based on morphological and…”
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Decoration of A-Ring of a Lupane-Type Triterpenoid with Different Oxygen and Nitrogen Heterocycles by Sousa, Joana L. C., Albuquerque, Hélio M. T., Silvestre, Armando J. D., Silva, Artur M. S.

“…Betulinic acid (BA) was used as starting building block to create a library of novel BA-derived compounds containing O- and N-heterocycles. Firstly, BA was…”
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A Stentless Modified Lich-Gregoir Technique for Safe Early Bladder Catheter Removal in Living and Deceased Kidney Transplants by Astolfi, Rafael H., Aguiar, Wilson F., Viana, Laila, Cristelli, Marina, Junior, Helio T.S, Pestana, Jose M.

“…To describe a stentless modified Lich-Gregoir technique (mLG) for ureteroneocystostomy in renal transplantation (RT), with early bladder catheter (BC) removal…”
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Chromeno[3,4- b ]xanthones as First-in-Class AChE and Aβ Aggregation Dual-Inhibitors by Malafaia, Daniela, Oliveira, Ana, Fernandes, Pedro A, Ramos, Maria J, Albuquerque, Hélio M T, Silva, Artur M S

“…Alzheimer's disease (AD) is a complex multifactorial disorder, mainly characterized by the progressive loss of memory and cognitive, motor, and functional…”
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N-acetylcysteine effects on extracellular polymeric substances of Xylella fastidiosa: A spatiotemporal investigation with implications for biofilm disruption by da Silva, Aldeliane M., Murillo, Duber M., Anbumani, Silambarasan, von Zuben, Antonio Augusto, Cavalli, Alessandro, Obata, Helio T., Fischer, Eduarda Regina, de Souza e Silva, Mariana, Bakkers, Erik, Souza, Alessandra A., Carvalho, Hernandes F., Cotta, Mônica A.

“…•We investigated the physical effects of N-acetylcysteine (NAC) on the bacteria Xylella fastidosa.•NAC acts mainly on EPS removal leading to the release of…”
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Triage strategy for urgent management of cardiac tamponade: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases by Ristić, Arsen D, Imazio, Massimo, Adler, Yehuda, Anastasakis, Aristides, Badano, Luigi P, Brucato, Antonio, Caforio, Alida L P, Dubourg, Olivier, Elliott, Perry, Gimeno, Juan, Helio, Tiina, Klingel, Karin, Linhart, Aleš, Maisch, Bernhard, Mayosi, Bongani, Mogensen, Jens, Pinto, Yigal, Seggewiss, Hubert, Seferović, Petar M, Tavazzi, Luigi, Tomkowski, Witold, Charron, Philippe

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Drug Discovery Based on Oxygen and Nitrogen (Non-)Heterocyclic Compounds Developed @LAQV–REQUIMTE/Aveiro by Sousa, Joana L. C., Albuquerque, Hélio M. T., Silva, Artur M. S.

“…Artur Silva’s research group has a long history in the field of medicinal chemistry. The development of new synthetic methods for oxygen (mostly polyphenols,…”
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Selective Induction of DNA Damage and Cell Cycle Arrest Mediated by Chromone‐Triazole Dyads Derivatives: Effects on Breast and Prostate Cancer Cells by Saher, Liza, Monteiro, Fátima L., Rocha, Djenisa H. A., Albuquerque, Hélio M. T., Silva, Artur M. S., Helguero, Luisa A.

“…Chromones and triazoles are groups of heterocyclic compounds widely known to exhibit a broad spectrum of biological activities. The combination of these two…”
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6-[(2S,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-5-fluoropyrimidine-4-carbaldehyde by Sousa, Joana L. C, Albuquerque, Hélio M. T, Silva, Artur M. S

“…Voriconazole (VN) is an antifungal drug indicated for the treatment of several fungal infections. Due to its side effects, some works involving late-stage…”
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A network approach to discerning the identities of C. elegans in a free moving population by Winter, Peter B., Brielmann, Renee M., Timkovich, Nicholas P., Navarro, Helio T., Castro, Andreia Cristiana Teixeira, Morimoto, Richard I., Amaral, Luis A. N.

“…The study of C. elegans has led to ground-breaking discoveries in gene-function, neuronal circuits, and physiological responses. Subtle behavioral phenotypes,…”
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2,2’-[(1E,1’E)-{[Hexa-2,4-diyne-1,6-diylbis(oxy)]bis(2,1-phenylene)}bis(ethene-2,1-diyl)]bis(4H-chromen-4-one) by Malafaia, Daniela, Sousa, Joana L. C., Silva, Artur M. S., Albuquerque, Hélio M. T.

“…2-Styrylchromones (2-SCs) are interesting compounds for their biological properties as well as versatility as starting materials for further transformations…”
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Pregnancy after renal transplantation: an evaluation of the graft function by Aivazoglou, Laís, Sass, Nelson, Silva, Hélio T, Sato, Jussara L, Medina-Pestana, José O, De Oliveira, Leandro G

“…Abstract Objectives To evaluate pregnancy outcomes and graft function in renal transplant recipients. Study design Thirty-four pregnancies in 31 patients were…”
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Clinical outcomes of myocarditis after SARS-CoV-2 mRNA vaccination in four Nordic countries: population based cohort study by Husby, Anders, Gulseth, Hanne Løvdal, Hovi, Petteri, Hansen, Jørgen Vinsløv, Pihlström, Nicklas, Gunnes, Nina, Härkänen, Tommi, Dahl, Jesper, Karlstad, Øystein, Heliö, Tiina, Køber, Lars, Ljung, Rickard, Hviid, Anders

“…ObjectiveTo investigate the clinical outcomes of myocarditis associated with mRNA vaccines against the SARS-CoV-2 virus compared with other types of…”
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1,6‐Conjugate Additions of Carbon Nucleophiles to 2‐[(1E,3E)‐4‐Arylbuta‐1,3‐dien‐1‐yl]‐4H‐chromen‐4‐ones by Albuquerque, Hélio M. T., Santos, Clementina M. M., Balanay, Mannix P., Cavaleiro, José A. S., Silva, Artur M. S.

“…The 1,6‐conjugate addition of nitromethane to 2‐[(1E,3E)‐4‐arylbuta‐1,3‐dien‐1‐yl]‐4H‐chromen‐4‐ones was accomplished and led mainly to the corresponding…”
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(E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as Synthons for the Synthesis of Xanthone-1,2,3-triazole Dyads by Albuquerque, Hélio M. T., Santos, Clementina M. M., Cavaleiro, José A. S., Silva, Artur M. S.

“…Xanthone‐1,2,3‐triazole dyads have been synthesized by two different approaches, both starting from novel (E)‐2‐(4‐arylbut‐1‐en‐3‐yn‐1‐yl)chromones, prepared…”
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