Search Results - "Helgason, A."
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A Reassessment of Genetic Diversity in Icelanders: Strong Evidence from Multiple Loci for Relative Homogeneity Caused by Genetic Drift
Published in Annals of human genetics (01-07-2003)“…Summary There has been some controversy in the literature concerning whether Icelanders are genetically homogenous or heterogeneous relative to other European…”
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Whole genome sequencing finds rare high-risk genotypes for hip osteoarthritis in the COMP and CHADL genes
Published in Osteoarthritis and cartilage (01-04-2017)Get full text
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Parental influence on human germline de novo mutations in 1,548 trios from Iceland
Published in Nature (London) (28-09-2017)Get full text
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Parental influence on human germline de novo mutations in 1,548 trios from Iceland
Published in Nature (London) (28-09-2017)“…Whole-genome sequencing data of 14,688 Icelanders, including 1,548 parent–offspring trios, show how the age and sex of parents affect the rate and spectrum of…”
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Differences between germline genomes of monozygotic twins
Published in Nature genetics (01-01-2021)“…Despite the important role that monozygotic twins have played in genetics research, little is known about their genomic differences. Here we show that…”
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Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant: A Case Report
Published in The Pediatric infectious disease journal (01-04-2022)“…Posthemorragic hydrocephalus is a relatively common condition in prematures, often requiring ventriculoperitoneal shunts. We report a case of…”
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Death talk: gender differences in talking about one's own impending death
Published in BMC palliative care (11-03-2014)“…According to common practice based on a generally agreed interpretation of Icelandic law on the rights of patients, health care professionals cannot discuss…”
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Awareness of husband's impending death from cancer and long-term anxiety in widowhood: a nationwide follow-up
Published in Palliative medicine (01-07-2004)“…Background: We investigated the predictors and long-term consequences of awareness time — the length of time a woman is aware of her husband's impending death…”
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Effectiveness of tobacco cessation interventions for different groups of tobacco users in Sweden: a study protocol for a national prospective cohort study
Published in BMJ open (01-01-2022)“…IntroductionTobacco is still one of the single most important risk factors among the lifestyle habits that cause morbidity and mortality in humans…”
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Electronic screen use and mental well-being of 10-12-year-old children
Published in European journal of public health (01-06-2013)“…Today's children spend a great deal of time viewing electronic screen material, but the consequences of such behaviors, if any, are unknown. This study sought…”
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Whole genome characterization of sequence diversity of 15,220 Icelanders
Published in Scientific data (21-09-2017)“…Understanding of sequence diversity is the cornerstone of analysis of genetic disorders, population genetics, and evolutionary biology. Here, we present an…”
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Long-term follow-up of a high- and a low-intensity smoking cessation intervention in a dental setting--a randomized trial
Published in BMC public health (19-06-2013)“…Achieving lifelong tobacco abstinence is an important public health goal. Most studies use 1-year follow-ups, but little is known about how good these are as…”
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Genetic evidence for a family-based Scandinavian settlement of Shetland and Orkney during the Viking periods
Published in Heredity (01-08-2005)“…The Viking age witnessed the expansion of Scandinavian invaders across much of northwestern Europe. While Scandinavian settlements had an enduring cultural…”
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CDKN2A mutations and melanoma risk in the Icelandic population
Published in Journal of medical genetics (01-05-2008)“…Germline CDKN2A mutations have been observed in 20-40% of high risk, melanoma prone families; however, little is known about their prevalence in population…”
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Comparison of the Cost-Effectiveness of a High- and a Low-Intensity Smoking Cessation Intervention in Sweden: A Randomized Trial
Published in Nicotine & tobacco research (01-09-2013)“…To assess the relative cost-effectiveness of a high-intensity treatment (HIT) and a low-intensity treatment (LIT) for smoking cessation. The societal and…”
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The beliefs about pros and cons of drinking and intention to change among hazardous and moderate alcohol users: a population-based cross-sectional study
Published in European journal of public health (01-08-2014)“…Fundamental to supporting hazardous alcohol users are the rationales for reducing alcohol intake highlighted by the users themselves. This study analyses the…”
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Decreased sexual capacity after external radiation therapy for prostate cancer impairs quality of life
Published in International journal of radiation oncology, biology, physics (1995)“…The aim of this study was to assess to what extent patients treated with radiation therapy for prostate cancer experience change in sexual functioning and to…”
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Factors associated with waning sexual function among elderly men and prostate cancer patients
Published in The Journal of urology (1997)“…We identified factors that affect sexual function in men 50 to 80 years old and, therefore, may confound the comparison among groups of elderly men. In…”
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Large-scale integration of the plasma proteome with genetics and disease
Published in Nature genetics (01-12-2021)“…The plasma proteome can help bridge the gap between the genome and diseases. Here we describe genome-wide association studies (GWASs) of plasma protein levels…”
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Urinary and bowel symptoms in men with and without prostate cancer: results from an observational study in the Stockholm area
Published in European urology (1998)“…To investigate the prevalence of urinary and bowel symptoms in population-based groups of men with and without prostate cancer. A self-administered…”
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