Search Results - "Helfricht, A"

RNF4 is required for DNA double-strand break repair in vivo by Vyas, R, Kumar, R, Clermont, F, Helfricht, A, Kalev, P, Sotiropoulou, P, Hendriks, I A, Radaelli, E, Hochepied, T, Blanpain, C, Sablina, A, van Attikum, H, Olsen, J V, Jochemsen, A G, Vertegaal, A C O, Marine, J-C

“…Unrepaired DNA double-strand breaks (DSBs) cause genetic instability that leads to malignant transformation or cell death. Cells respond to DSBs with the…”
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Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4 by Pfeiffer, Annika, Luijsterburg, Martijn S, Acs, Klara, Wiegant, Wouter W, Helfricht, Angela, Herzog, Laura K, Minoia, Melania, Böttcher, Claudia, Salomons, Florian A, van Attikum, Haico, Dantuma, Nico P

“…The SUMO‐targeted ubiquitin ligase RNF4 functions at the crossroads of the SUMO and ubiquitin systems. Here, we report that the deubiquitylation enzyme (DUB)…”
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Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome by Helfricht, Angela, Thijssen, Peter E, Rother, Magdalena B, Shah, Rashmi G, Du, Likun, Takada, Sanami, Rogier, Mélanie, Moritz, Jacques, IJspeert, Hanna, Stoepker, Chantal, van Ostaijen-Ten Dam, Monique M, Heyer, Vincent, Luijsterburg, Martijn S, de Groot, Anton, Jak, Rianca, Grootaers, Gwendolynn, Wang, Jun, Rao, Pooja, Vertegaal, Alfred C O, van Tol, Maarten J D, Pan-Hammarström, Qiang, Reina-San-Martin, Bernardo, Shah, Girish M, van der Burg, Mirjam, van der Maarel, Silvère M, van Attikum, Haico

“…The autosomal recessive immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a genetically heterogeneous disorder. Despite the…”
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Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) Regulates γ-Histone 2AX (γ-H2AX) Levels upon Ionizing Radiation by Neumayer, Gernot, Helfricht, Angela, Shim, Su Yeon, Le, Hoa Thi, Lundin, Cecilia, Belzil, Camille, Chansard, Mathieu, Yu, Yaping, Lees-Miller, Susan P., Gruss, Oliver J., van Attikum, Haico, Helleday, Thomas, Nguyen, Minh Dang

“…The microtubule-associated protein targeting protein for Xenopus kinesin-like protein 2 (TPX2) plays a key role in spindle assembly and is required for mitosis…”
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