Search Results - "Helena Poliselli Farsky, Sandra"
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Xenobiotics Delivered by Electronic Nicotine Delivery Systems: Potential Cellular and Molecular Mechanisms on the Pathogenesis of Chronic Kidney Disease
Published in International journal of molecular sciences (07-09-2022)“…Chronic kidney disease (CKD) is characterized as sustained damage to the renal parenchyma, leading to impaired renal functions and gradually progressing to…”
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Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood–Brain Barrier Model
Published in International journal of molecular sciences (24-10-2022)“…Biological mediators secreted during peripheral chronic inflammation reach the bloodstream and may damage the blood–brain barrier (BBB), triggering central…”
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Novel site-specific PEGylated L-asparaginase
Published in PloS one (12-02-2019)“…L-asparaginase (ASNase) from Escherichia coli is currently used in some countries in its PEGylated form (ONCASPAR, pegaspargase) to treat acute lymphoblastic…”
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Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab in Murine Experimental Colitis and Crohn's Disease
Published in Frontiers in immunology (17-09-2021)“…Non-responsiveness to anti-TNF-α therapies presents relevant rates in inflammatory bowel disease patients, presenting the need to find biomarkers involved in…”
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Direct effects of poly(ε-caprolactone) lipid-core nanocapsules on human immune cells
Published in Nanomedicine (London, England) (01-06-2019)“…Poly(ε-caprolactone) lipid-core nanocapsules (LNCs) are efficient drug carriers and drug-free LNCs display therapeutic effects, inhibiting tumor growth and…”
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Beneficial effects of Red Light-Emitting Diode treatment in experimental model of acute lung injury induced by sepsis
Published in Scientific reports (04-10-2017)“…Sepsis is a severe disease with a high mortality index and it is responsible for the development of acute lung injury (ALI). We evaluated the effects of…”
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Control of expression and activity of peroxisome proliferated‐activated receptor γ by Annexin A1 on microglia during efferocytosis
Published in Cell biochemistry and function (01-10-2019)“…Annexin A1 (AnxA1) is a protein secreted by phagocytic cells which plays a pivotal role on the resolution of inflammation by enhancing phagocytosis carried out…”
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Exogenous glutamine impairs neutrophils migration into infections sites elicited by lipopolysaccharide by a multistep mechanism
Published in Amino acids (01-03-2019)“…Glutamine (GLN) is the most abundant free amino acid in the body, and is considered as a conditionally essential amino acid under stress conditions, acting as…”
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Cisplatin treatment modulates Annexin A1 and inhibitor of differentiation to DNA 1 expression in cervical cancer cells
Published in Biomedicine & pharmacotherapy (01-09-2020)“…[Display omitted] •ID1 expression is increased in Cervical Intraepithelial Neoplasia.•The cisplatin (Cis) interfere molecularly on ANXA1 and ID1 in the…”
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Annexin A12–26 Treatment Improves Skin Heterologous Transplantation by Modulating Inflammation and Angiogenesis Processes
Published in Frontiers in pharmacology (10-09-2018)“…Skin graft successful depends on reduction of local inflammation evoked by the surgical lesion and efficient neovascularization to nutrition the graft. It has…”
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Beneficial effects of vitamin C treatment on pregnant rats exposed to formaldehyde: Reversal of immunosuppression in the offspring
Published in Toxicology and applied pharmacology (01-06-2016)“…Inhalation of formaldehyde (FA) during the pregnancy induces oxidative stress in the uterus, and here we hypothesized that this mechanism may be responsible…”
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Hyaluronidase decreases neutrophils infiltration to the inflammatory site
Published in Inflammation research (01-07-2016)“…Objective To evaluate the in vivo anti-inflammatory potential of bovine hyaluronidase (HYAL) using two different models of acute inflammation. Methods Air…”
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Young “Healthy” Smokers Have Functional and Inflammatory Changes in the Nasal and the Lower Airways
Published in Chest (01-05-2014)“…Background Smoking is responsible for most COPD. Although people with COPD often have concomitant nasal disease, there are few studies that report physiologic…”
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Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
Published in International journal of nanomedicine (01-01-2015)“…Fully dispersible, cationic ultrasmall (7 nm diameter) superparamagnetic iron oxide nanoparticles, exhibiting high relaxivity (178 mM(-1)s(-1) in 0.47 T) and…”
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Photobiomodulation Therapy Decreases Oxidative Stress in the Lung Tissue after Formaldehyde Exposure: Role of Oxidant/Antioxidant Enzymes
Published in Mediators of inflammation (01-01-2016)“…Formaldehyde is ubiquitous pollutant that induces oxidative stress in the lung. Several lung diseases have been associated with oxidative stress and their…”
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Intracellular mechanisms of hydroquinone toxicity on endotoxin-activated neutrophils
Published in Archives of toxicology (01-11-2012)“…Circulating neutrophils promptly react to different substances in the blood and orchestrate the beginning of the innate inflammatory response. We have shown…”
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scFv-Anti-LDL(-)-Metal-Complex Multi-Wall Functionalized-Nanocapsules as a Promising Tool for the Prevention of Atherosclerosis Progression
Published in Frontiers in medicine (20-04-2021)“…Atherosclerosis can be originated from the accumulation of modified cholesterol-rich lipoproteins in the arterial wall. The electronegative LDL, LDL(-), plays…”
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Hydroquinone Stimulates Inflammatory Functions in Microvascular Endothelial Cells via NF‐κB Nuclear Activation
Published in Basic & clinical pharmacology & toxicology (01-11-2011)“…: Hydroquinone impairs several leucocyte cell functions, which alter the immune response. Although endothelial cell functions are important for the…”
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Anacardic Acids from Cashew Nuts Ameliorate Lung Damage Induced by Exposure to Diesel Exhaust Particles in Mice
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…Anacardic acids from cashew nut shell liquid, a Brazilian natural substance, have antimicrobial and antioxidant activities and modulate immune responses and…”
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Toxic mechanisms of cigarette smoke and heat-not-burn tobacco vapor inhalation on rheumatoid arthritis
Published in The Science of the total environment (25-02-2022)“…Tobacco combustion exposure worsens rheumatoid arthritis (RA). Non-combustible tobacco devices, as heat-not-burn tobacco (HNBT), are emerging as harm reduction…”
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