Search Results - "Helen Fitton, J"

Therapies from Fucoidan: New Developments by Fitton, Helen J, Stringer, Damien S, Park, Ah Young, Karpiniec, Samuel N

“…Since our last review in 2015, the study and use of fucoidan has extended in several research areas. Clinical use of fucoidan for the treatment of renal…”
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Fucoidan and Lung Function: Value in Viral Infection by Fitton, J Helen, Park, Ah Young, Karpiniec, Samuel S, Stringer, Damien N

“…Compromised lung function is a feature of both infection driven and non-infective pathologies. Viral infections-including the current pandemic strain…”
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Anti-Inflammatory Activity of Fucoidan Extracts In Vitro by Ahmad, Tauseef, Eapen, Mathew Suji, Ishaq, Muhammad, Park, Ah Young, Karpiniec, Samuel S, Stringer, Damien N, Sohal, Sukhwinder Singh, Fitton, J Helen, Guven, Nuri, Caruso, Vanni, Eri, Rajaraman

“…Fucoidans are sulfated, complex, fucose-rich polymers found in brown seaweeds. Fucoidans have been shown to have multiple bioactivities, including…”
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Fucoidan Extracts Ameliorate Acute Colitis by Lean, Qi Ying, Eri, Rajaraman D, Fitton, J Helen, Patel, Rahul P, Gueven, Nuri

“…Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, are an important cause of morbidity and impact significantly on quality of…”
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Improved Plasma Lipids, Anti-Inflammatory Activity, and Microbiome Shifts in Overweight Participants: Two Clinical Studies on Oral Supplementation with Algal Sulfated Polysaccharide by Roach, Lauren A, Meyer, Barbara J, Fitton, J Helen, Winberg, Pia

“…Seaweed polysaccharides in the diet may influence both inflammation and the gut microbiome. Here we describe two clinical studies with an Ulva sp. 84-derived…”
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Fucoidan Independently Enhances Activity in Human Immune Cells and Has a Cytostatic Effect on Prostate Cancer Cells in the Presence of Nivolumab by Park, Ah Young, Nafia, Imane, Stringer, Damien N, Karpiniec, Samuel S, Fitton, J Helen

“…Fucoidan compounds may increase immune activity and are known to have cancer inhibitory effects in vitro and in vivo. In this study, we aimed to investigate…”
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Oral Supplementation with Algal Sulphated Polysaccharide in Subjects with Inflammatory Skin Conditions: A Randomised Double-Blind Placebo-Controlled Trial and Baseline Dietary Differences by Roach, Lauren A, Meyer, Barbara J, Fitton, J Helen, Winberg, Pia

“…We examined the effect of a dietary seaweed extract-sulfated xylorhamnoglucuronan (SXRG84)-on individuals with inflammatory skin conditions. A subgroup…”
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Fucoidan Supplementation Restores Fecal Lysozyme Concentrations in High-Performance Athletes: A Pilot Study by Cox, Amanda J, Cripps, Allan W, Taylor, Phillipa A, Fitton, J Helen, West, Nicholas P

“…Nutritional strategies to help promote immune competence are of particular interest for a range of population groups. This study aimed to assess the potential…”
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Micro RNA Expression after Ingestion of Fucoidan; A Clinical Study by Gueven, Nuri, Spring, Kevin J, Holmes, Sandra, Ahuja, Kiran, Eri, Raj, Park, Ah Young, Fitton, J Helen

“…Fucoidans are a class of fucose-rich sulfated polysaccharides derived from brown macroalgae that exert a range of biological activities in vitro and in vivo…”
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The Effect of Undaria pinnatifida Fucoidan on the Pharmacokinetics of Letrozole and Tamoxifen in Patients With Breast Cancer by Tocaciu, Shreya, Oliver, Lesley J., Lowenthal, Ray M., Peterson, Gregory M., Patel, Rahul, Shastri, Madhur, McGuinness, Georgia, Olesen, Inger, Fitton, J. Helen

“…Background: Although the use of complementary and alternative medicines is widespread in cancer patients, clinical evidence of their benefits is sparse…”
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Oral Fucoidan Attenuates Lung Pathology and Clinical Signs in a Severe Influenza a Mouse Model by Richards, Claire, Williams, Neil A, Fitton, J Helen, Stringer, Damien N, Karpiniec, Samuel S, Park, Ah Young

“…Fucoidans are known to be effective inhibitors of inflammation, and of virus binding and cellular entry. -derived fucoidan (UPF) was assessed in a severe…”
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Pathway Analysis of Fucoidan Activity Using a Yeast Gene Deletion Library Screen by Corban, Monika, Ambrose, Mark, Pagnon, Joanne, Stringer, Damien, Karpiniec, Sam, Park, Ahyoung, Eri, Raj, Fitton, J Helen, Gueven, Nuri

“…Fucoidan, the sulfated fucose-rich polysaccharide derived from brown macroalgae, was reported to display some anti-cancer effects in in vitro and in vivo…”
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Pilot clinical study to evaluate the anticoagulant activity of fucoidan by Irhimeh, Mohammad R, Fitton, J Helen, Lowenthal, Ray M

“…Seaweed-derived heparin-like substances such as fucoidan have been extensively studied in vitro as potential blood anticoagulants. However, there have been no…”
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Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells by Irhimeh, Mohammad R, Fitton, J. Helen, Lowenthal, Raymond M

“…Objective Transplantation of hematopoietic progenitor stem cells (HPC) is an important treatment modality for a variety of neoplastic diseases. HPC collection…”
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Modulation of Gene Expression in a Sterile Atopic Dermatitis Model and Inhibition of Staphylococcus aureus Adhesion by Fucoidan by Park, Ah Young, Bourtembourg, Maureen, Chrétien, Aline, Hubaux, Roland, Lancelot, Céline, Salmon, Michel, Fitton, J Helen

“…Atopic dermatitis is a multifactorial pathology that includes perturbations of gene expression and increased adhesion of Fucoidans are seaweed-derived sulfated…”
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Topical Benefits of Two Fucoidan-Rich Extracts from Marine Macroalgae by Fitton, J., Dell'Acqua, Giorgio, Gardiner, Vicki-Anne, Karpiniec, Samuel, Stringer, Damien, Davis, Emma

“…Two concentrated and well-characterized fucoidan-rich extracts were investigated to determine their benefits in topical applications. An Undaria pinnatifida…”
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A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis by Myers, Stephen P

“…Tests a Maritech® seaweed extract nutrient complex containing a blend of extracts from three different species of brown algae plus nutrients zinc, manganese…”
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A combined Phase I and II open-label study on the immunomodulatory effects of seaweed extract nutrient complex by Myers, Stephen P

“…Reports the findings of an exploratory study which aimed to determine whether a seaweed nutrient complex containing a blend of extracts from three different…”
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Are seaweed-derived fucoidans possible future anti-cancer agents? by Lowenthal, Ray M., Fitton, J. Helen

“…Is there a role for brown macroalgae-derived fucoidan in cancer therapeutics? This review discusses the in vitro, in vivo and clinical data concerning fucoidan…”
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Formation of an adherent hematopoietic expansion culture using fucoidan by Irhimeh, Mohammad R., Fitton, J. Helen, Ko, Kap-Hyoun, Lowenthal, Ray M., Nordon, Robert E.

“…Expansion of transplantable cord blood (CB) progenitors using a stroma requires provision of an exogenous cell source because of the low frequency of stromal…”
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