Search Results - "Helder, MN"

A novel approach revealing the effect of a collagenous membrane on osteoconduction in maxillary sinus floor elevation with β-tricalcium phosphate by Schulten, Engelbert A J M, Prins, Henk-Jan, Overman, Janice R, Helder, Marco N, ten Bruggenkate, Christiaan M, Klein-Nulend, Jenneke

“…Calcium phosphates are used in maxillary sinus floor elevation (MSFE) procedures to increase bone height prior to dental implant placement. Whether a…”
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Codelivery of doxorubicin and JIP1 siRNA with novel EphA2-targeted PEGylated cationic nanoliposomes to overcome osteosarcoma multidrug resistance by Haghiralsadat, Fateme, Amoabediny, Ghasem, Naderinezhad, Samira, Zandieh-Doulabi, Behrouz, Forouzanfar, Tymour, Helder, Marco N

“…Osteosarcoma (OS) mostly affects children and young adults, and has only a 20%-30% 5-year survival rate when metastasized. We aimed to create dual-targeted…”
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Design and fabrication of a hybrid alginate hydrogel/poly(ε‐caprolactone) mold for auricular cartilage reconstruction by Visscher, D. O., Gleadall, A., Buskermolen, J. K., Burla, F., Segal, J., Koenderink, G. H., Helder, M. N., van Zuijlen, P. P. M.

“…The aim of this study was to design and manufacture an easily assembled cartilage implant model for auricular reconstruction. First, the printing accuracy and…”
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Telomerase and Telomeres: From Basic Biology to Cancer Treatment by Helder, Marco N., Wisman, G. Bea A., van der Zee, Ate G. J.

“…The limited capacity to divide is one of the major differences between normal somatic cells and cancerous cells. This 'finite life span' of somatic cells is…”
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Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure by Oedayrajsingh-Varma, M.J., van Ham, S.M., Knippenberg, M., Helder, M.N., Klein-Nulend, J., Schouten, T.E., Ritt, M.J.P.F., van Milligen, F.J.

“…Adipose tissue contains a stromal vascular fraction that can be easily isolated and provides a rich source of adipose tissue-derived mesenchymal stem cells…”
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Significance of immunohistochemistry biomarkers in prediction of malignant transformation of oral lichen planus: A systematic review by Al-Jamaei, AA, Subramanyam, RV, Helder, MN, Forouzanfar, T., Ruslin, M., Meij, EV, Visscher, JG

“…BACKGROUNDOral lichen planus (OLP) is a chronic inflammatory disorder with increased risk for malignant transformation. Biomarker validation is a pivotal step…”
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Osteogenesis versus chondrogenesis by BMP-2 and BMP-7 in adipose stem cells by Knippenberg, M., Helder, M.N., Zandieh Doulabi, B., Wuisman, P.I.J.M., Klein-Nulend, J.

“…Bone morphogenetic proteins (BMPs) initiate, promote, and maintain chondrogenesis and osteogenesis. We hypothesize that BMP-2 induces an osteogenic, and BMP-7…”
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Adipose tissue-derived mesenchymal stem cells acquire bone cell-like responsiveness to fluid shear stress on osteogenic stimulation by Knippenberg, Marlene, Helder, Marco N, Doulabi, Behrouz Zandieh, Semeins, Cornelis M, Wuisman, Paul I J M, Klein-Nulend, Jenneke

“…To engineer bone tissue, mechanosensitive cells are needed that are able to perform bone cell-specific functions, such as (re)modeling of bone tissue. In vivo,…”
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The polymine spermine regulates osteogenic differentiation in adipose stem cells by Tjabringa, G.S., Zandieh‐Doulabi, B., Helder, M.N., Knippenberg, M., Wuisman, P.I.J.M., Klein‐Nulend, J.

“…For bone tissue engineering, it is important that mesenchymal stem cells (MSCs) differentiate into osteoblasts. To develop a method for differentiation of…”
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JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin by Fokkema, Eelco, Groen, Harry J.M, Helder, Marco N, de Vries, Elisabeth G.E, Meijer, Coby

“…The aim of this study is to establish anti-tumour potency of the new oral platinum drug JM216 and its metabolite JM118 in relation to the platinum (Pt)-DNA…”
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Non-steroidal factors in bovine follicular fluid inhibit or facilitate the action of pulsatile administration of GnRH on LH release in the female rat by van Dieten, JA, Helder, MN, van den Oever, C, de Koning, J

“…Using steroid-free bovine follicular fluid (bFF), we studied the action of gonadotrophin surge-inhibiting factor/attenuating factor (GnSIF/AF) on GnRH-induced…”
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Expression pattern of osteogenic protein-1 (bone morphogenetic protein- 7) in human and mouse development by Helder, MN, Ozkaynak, E, Sampath, KT, Luyten, FP, Latin, V, Oppermann, H, Vukicevic, S

“…Osteogenic protein-1 (OP-1; BMP-7) is a member of the bone morphogenetic protein subfamily. Because members of the TGF-beta superfamily have a role in tissue…”
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Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer by Wisman, G. Bea A., Knol, Ageeth J., Helder, Marco N., Krans, Mindert, de Vries, Elisabeth G.E., Hollema, Harry, de Jong, Steven, van der Zee, Ate G.J.

“…We investigated, in cervical cancer, the relation between telomerase activity, telomerase RNA (hTR) and mRNA of the catalytic subunit of telomerase, hTERT,…”
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Telomerase in (pre)neoplastic cervical disease by Wisman, G.B.A., De Jong, Steven, Meersma, Gert Jan, Helder, Marco N., Hollema, Harry, de Vries, Elisabeth G.E., Keith, W.Nicol, van der Zee, Ate G.J.

“…This study was performed to determine upregulation of the human telomerase RNA component (hTR) and mRNA of the catalytic subunit of telomerase (hTERT) in…”
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Detection of telomerase, its components, and human papillomavirus in cervical scrapings as a tool for triage in women with cervical dysplasia by Reesink-Peters, N, Helder, M N, Wisman, G B A, Knol, A J, Koopmans, S, Boezen, H M, Schuuring, E, Hollema, H, de Vries, E G E, de Jong, S, van der Zee, A G J

“…Aim: To examine whether the detection of either telomerase and its components or high risk human papillomavirus (HPV) are of value in predicting the presence…”
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Bone morphogenetic protein-7 (osteogenic protein-1, OP-1) and tooth development by Helder, M N, Karg, H, Bervoets, T J, Vukicevic, S, Burger, E H, D'Souza, R N, Wöltgens, J H, Karsenty, G, Bronckers, A L

“…Bone morphogenetic proteins (BMPs) form a family of growth factors originally isolated from extracellular bone matrix that are capable of inducing bone…”
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Prostaglandins differentially affect osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells by Knippenberg, M, Helder, M N, de Blieck-Hogervorst, J M A, Wuisman, P I J M, Klein-Nulend, J

“…Adipose tissue-derived mesenchymal stem cells (AT-MSCs) are currently used for bone tissue engineering. AT-MSCs undergoing osteogenic differentiation respond…”
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Specific gonadotrophin-releasing hormone analogue binding predominantly in human luteinized follicular aspirates and not in human pre-ovulatory follicles by Brus, L, Lambalk, C B, de Koning, J, Helder, M N, Janssens, R M, Schoemaker, J

“…In an attempt to resolve the apparent controversy in the observed effects of gonadotrophin-releasing hormone (GnRH) analogues on the ovary, conventional…”
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Telomerase in relation to expression of p53, c-Myc and estrogen receptor in ovarian tumours by Wisman, G Bea A, Hollema, Harry, Helder, Marco N, Knol, Ageeth J, Van der Meer, Gretha T, Krans, Mindert, De Jong, Steven, De Vries, Elisabeth G E, Van der Zee, Ate G J

“…Telomerase activity and its subunits (hTERC, hTERT mRNA) were evaluated in ovarian tumours in relation to the expression of p53, c-Myc and estrogen receptor…”
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Developing human lung and kidney are major sites for synthesis of bone morphogenetic protein-3 (osteogenin) by Vukicevic, S, Helder, MN, Luyten, FP

“…Bone morphogenetic protein-3 (BMP-3; osteogenin) is a member of the transforming growth factor-beta superfamily. We used human BMP-3 cDNA probes and a specific…”
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