Search Results - "Held, K.D."

LET-dependent Differences in Bystander Stimulation Induced by X-rays and Charged Particle Irradiation in Chondrosarcoma Cells by Wakatsuki, M, Magpayo, N, Held, K.D

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Identification of Radiosensitizing Targeted Drugs and Associated Genomic Biomarkers by a Cell Line Screening Platform by Willers, H, Wang, M, Liu, Q, Kern, A, Hong, T.S, Held, K.D, Benes, C, Efstathiou, J

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The Lack of a Bystander Response Induced by Photon Irradiation in Chondrosarcoma Cells by Wakatsuki, M, Magpayo, N, Held, K.D

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Survey of Radiation Biology Educators in U.S. and Canadian Radiation Oncology Residency Programs by Rosenstein, B.S, Held, K.D, Williams, J, Rockwell, S, Zeman, E.M

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The Role of FANCD2 in Determining Cellular Resistance to Ionizing Radiation by Kuhnert, V.M, Kachnic, L.A, Li, L, Purschke, M, Lee, R, Dunst, J, Held, K.D, Willers, H

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Radiation-Activated Prodrugs: An Investigation of Optimal Linker Chemistries and Radiation Parameters by Banla, L.I., Quintana, J., Olberg, S., Ng, T.S.C., Schuemann, J.P., Held, K.D., Hwang, W.L., Miller, M.A.

“…Radicals generated by ionizing radiation (IR) can drive specific chemical reactions. This phenomenon underpins radiation-dependent prodrugs (RPDs), which are…”
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TOPAS-nBio: An Extension to the TOPAS Simulation Toolkit for Cellular and Sub-cellular Radiobiology by Schuemann, J., McNamara, A. L., Ramos-Méndez, J., Perl, J., Held, K. D., Paganetti, H., Incerti, S., Faddegon, B.

“…The TOPAS Monte Carlo (MC) system is used in radiation therapy and medical imaging research, having played a significant role in making Monte Carlo simulations…”
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Parathyroid Hormone Reduces Persistent Proton Induced DNA Double-Strand Breaks in Osteocytes by Otani, Y., Otani, K., Okonogi, N., Divieti Pajevic, P., Xie, Y., Depauw, N., Paganetti, H., Schuemann, J.P., Held, K.D., Miyamoto, D.T., McNamara, A.L.

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A New Standard DNA Damage (SDD) Data Format by Schuemann, J., McNamara, A. L., Warmenhoven, J. W., Henthorn, N. T., Kirkby, K. J., Merchant, M. J., Ingram, S., Paganetti, H., Held, K. D., Ramos-Mendez, J., Faddegon, B., Perl, J., Goodhead, D. T., Plante, I., Rabus, H., Nettelbeck, H., Friedland, W., Kundrát, P., Ottolenghi, A., Baiocco, G., Barbieri, S., Dingfelder, M., Incerti, S., Villagrasa, C., Bueno, M., Bernal, M. A., Guatelli, S., Sakata, D., Brown, J. M. C., Francis, Z., Kyriakou, I., Lampe, N., Ballarini, F., Carante, M. P., Davídková, M., Štěpán, V., Jia, X., Cucinotta, F. A., Schulte, R., Stewart, R. D., Carlson, D. J., Galer, S., Kuncic, Z., Lacombe, S., Milligan, J., Cho, S. H., Sawakuchi, G., Inaniwa, T., Sato, T., Li, W., Solov'yov, A. V., Surdutovich, E., Durante, M., Prise, K. M., McMahon, S. J.

“…Our understanding of radiation-induced cellular damage has greatly improved over the past few decades. Despite this progress, there are still many obstacles to…”
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P1521Classification of cardiovascular causes of death for radiation epidemiologic studies: initial application to cohorts of radiation workers, radiographers, and atomic veterans by Einstein, A.J., Sesso, H.D., Cohen, S.S., Boerma, M., Chambers, C., Darby, S., Gerber, T.C., Hirshfeld, J., Little, M.P., Mulrooney, D.A., Held, K.D., Boice, J.D.

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Molecular Mechanism of PD-L1 Upregulation in Cancer Cells after X-Ray Irradiation by Sato, H., Niimi, A., Yasuhara, T., Isono, M., Permata, T.B.M., Sekine, R., Oike, T., Nuryadi, E., Kakoti, S., Yoshimoto, Y., Held, K.D., Suzuki, Y., Kono, K., Miyagawa, K., Nakano, T., Shibata, A.

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Effects of polyamines and thiols on the radiation sensitivity of bacterial transforming DNA by Held, K D, Awad, S

“…The effects of polyamines on the loss of biological activity of bacterial transforming DNA irradiated in the absence and presence of sulphydryl-containing…”
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Low-Dose Studies of Bystander Cell Killing with Targeted Soft X Rays by Schettino, G., Folkard, M., Prise, K. M., Vojnovic, B., Held, K. D., Michael, B. D.

“…Schettino, G., Folkard, M., Prise, K. M., Vojnovic, B., Held, K. D. and Michael, B. D. Low-Dose Studies of Bystander Cell Killing with Targeted Soft X Rays…”
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Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria by Tartier, L, McCarey, Y L, Biaglow, J E, Kochevar, I E, Held, K D

“…Previous studies have shown that under certain conditions some thiol-containing compounds can cause apoptosis in a number of different cell lines. Herein, we…”
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Effects of trypanothione on the biological activity of irradiated transforming DNA by Awad, S, Henderson, G B, Cerami, A, Held, K D

“…Held et al. (1984a,b) demonstrated previously that glutathione (GSH), a negatively charged thiol, is significantly less efficient in the hydrogen atom donation…”
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The oxygen effect: variation of the K-value and lifetimes of O2-dependent damage in some glutathione-deficient mutants of Escherichia coli by Harrop, H A, Held, K D, Michael, B D

“…Radiosensitization by various concentrations of O2 has been studied in an Escherichia coli K-12 wild-type strain and some derived glutathione (GSH)-deficient…”
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Interactions of Radioprotectors and Oxygen in Cultured Mammalian Cells: I. Dithiothreitol Effects on Radiation-Induced Cell Killing by Held, Kathryn D.

“…Radioprotection in vitro by sulfhydryl (SH)-containing compounds is usually greater in aerated than in hypoxic cells. This observation has been cited recently…”
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Effect of varying the concentration of damage restituting species in the radical repair model by Epp, E R, Held, K D, Clark, E P, Biaglow, J E

“…From analytical expressions derived for the radical-repair (competition) model describing the relationship between cellular radiosensitivity and oxygen…”
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Ultrafast chemical repair of DNA single and double strand break precursors in irradiated V79 cells by Michael, B D, Davies, S, Held, K D

“…The fast kinetics of reactions of free radical precursors of DNA single strand breaks (ssb) and double strand breaks (dsb) have been determined in Chinese…”
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Pulse Radiolysis Studies of the Interactions of the Sulfhydryl Compound Dithiothreitol and Sugars by Held, Kathryn D., Harrop, Hilary A., Michael, Barry D.

“…Pulse radiolysis studies of the hydrogen atom transfer ("repair") reaction from the sulfhydryl-containing (RSH) compound dithiothreitol (DTT) to the DNA sugar…”
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