Search Results - "Held, James P."

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  1. 1

    Multiple distinct evolutionary mechanisms govern the dynamics of selfish mitochondrial genomes in Caenorhabditis elegans by Gitschlag, Bryan L., Pereira, Claudia V., Held, James P., McCandlish, David M., Patel, Maulik R.

    Published in Nature communications (19-09-2024)
    “…Cells possess multiple mitochondrial DNA (mtDNA) copies, which undergo semi-autonomous replication and stochastic inheritance. This enables mutant mtDNA…”
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    Journal Article
  2. 2

    Functional conservation of mitochondrial RNA levels despite divergent mtDNA organization by Held, James P, Patel, Maulik R

    Published in BMC research notes (11-07-2020)
    “…Mitochondria-encoded ribosomal RNA (rRNA) genes in humans are expressed at a higher rate than protein coding genes of the mitochondria. The organization of the…”
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    Journal Article
  3. 3

    A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response by Held, James P, Feng, Gaomin, Saunders, Benjamin R, Pereira, Claudia V, Burkewitz, Kristopher, Patel, Maulik R

    Published in eLife (22-04-2022)
    “…The mitochondrial unfolded protein response (UPR ) has emerged as a predominant mechanism that preserves mitochondrial function. Consequently, multiple…”
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  4. 4

    Tissue-specific heteroplasmy segregation is accompanied by a sharp mtDNA decline in Caenorhabditis elegans soma by Tsyba, Nikita, Feng, Gaomin, Grub, Lantana K., Held, James P., Strozak, Adrianna M., Burkewitz, Kristopher, Patel, Maulik R.

    Published in iScience (21-04-2023)
    “…Mutations in the mitochondrial genome (mtDNA) can be pathogenic. Owing to the multi-copy nature of mtDNA, wild-type copies can compensate for the effects of…”
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    Journal Article
  5. 5

    Combination of Novel Mutation in FAD3C and FAD3A for Low Linolenic Acid Soybean by Held, James P., Carrero‐Colón, Militza, Hudson, Karen A.

    Published in Agrosystems, geosciences & environment (01-01-2019)
    “…Core Ideas New low linolenic soybean with novel alleles of FAD3A and FAD3C. Mutation in GmFAD3C reduces linolenic acid levels. Soybean FAD3C controls linolenic…”
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  6. 6

    RNA: De-silencing to the rescue by Held, James P, Patel, Maulik R

    Published in Current biology (17-06-2024)
    “…The fate of transcribed RNA dictates cellular function. A new study finds that mutations in specific RNA processing machinery genes result in de-silencing of a…”
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    Journal Article
  7. 7

    A viable hypomorphic mutation in the mitochondrial ribosome subunit, MRPS-31, exhibits mitochondrial dysfunction in C. elegans by Jozwik, Kylie M, Held, James P, Hecht, Chloe A, Patel, Maulik R

    Published in microPublication biology (2024)
    “…The mitochondrial ribosome (mitoribosome) translates mitochondrial genome encoded proteins essential for cellular energy production. Given this critical role,…”
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  8. 8

    The female orgasm: pelvic contractions by Bohlen, J G, Held, J P, Sanderson, M O, Ahlgren, A

    Published in Archives of sexual behavior (01-10-1982)
    “…Eleven nulliparous women manually self-stimulated to orgasm, each on three separate occasions. Pelvic contraction pressure was measured by an anal probe and a…”
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  9. 9

    The male orgasm: pelvic contractions measured by anal probe by Bohlen, J G, Held, J P, Sanderson, M O

    Published in Archives of sexual behavior (01-12-1980)
    “…Pelvic muscle contractions during sexual response can be monitored conveniently by the anal probe method described. Eleven young adult male subjects were each…”
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    Journal Article
  10. 10

    Development of a woman's multiple orgasm pattern: A research case report by Bohlen, Joseph G., Held, James P., Sanderson, Margaret Olwen, Boyer, Carol M.

    Published in The Journal of sex research (01-05-1982)
    “…A 36-year-old woman with limited previous sexual experience was repeatedly monitored as she learned to stimulate herself digitally to orgasm. During 7…”
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  11. 11

    Heart rate, rate-pressure product, and oxygen uptake during four sexual activities by Bohlen, J G, Held, J P, Sanderson, M O, Patterson, R P

    Published in Archives of internal medicine (1960) (01-09-1984)
    “…Heart rate, rate-pressure product, and VO2 were measured in ten healthy men during four specified sexual activities: coitus with husband on top, coitus with…”
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  12. 12

    The evaluation of sexual health services in a medical setting by Held, J P, Logan, C, Maddock, J W, Weiss, D S, Cole, T M

    Published in Journal of sex & marital therapy (01-01-1977)
    “…An interdisciplinary Sexual Health Services unit has been established at the University of Minnesota Medical School that offers counseling and treatment…”
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  13. 13

    The Evaluation of Sexual Health Services in a Medical Setting by Held, James P

    “…An interdisciplinary Sexual Health Services unit has been established at the University of Minnesota Medical School that offers counseling and treatment…”
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    Journal Article
  14. 14

    Automated data acquisition and analysis in muscle physiology research by Stanley, 3rd, T E, Held, J P, Estrin, J A

    “…Research in muscle physiology has progressed in both the volume and complexity of data examined. Dependence on manual methods to analyze and condense this…”
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    The Care and Feeding of Small-Group Leaders of Sex Discussion Groups by Held, James P, Rosenberg, Pearl P

    “…This paper focuses on the selection, training, and monitoring of the small group leaders in an extensive program of sex education. It discusses leadership…”
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    Journal Article
  17. 17

    A conceptual model for attitude assessment in all areas of medical education by Marcotte, D B, Held, J P

    Published in Journal of medical education (01-04-1978)
    “…In most medical schools attitudinal goals are confined to special courses in the curriculum and, as such, remain isolated. Failure to attend to both…”
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    The care and feeding of small-group leaders of sex discussion groups by Held, J P, Rosenberg, P P

    Published in Journal of sex & marital therapy (01-01-1978)
    “…This paper will focus on the selection, training, and monitoring of the small-group leaders in an extensive program of sex education. While not explicitly…”
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    Journal Article
  20. 20

    A shared conceptual schema for four medical expert systems by Held, J.P., Carlis, J.V., Ludwig, T.

    “…The fundamental reason for database management systems is the support of applications using shared overlapping sets of data through external views of an…”
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    Conference Proceeding