Search Results - "Helbig, Roger"
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Splice-site mutations cause Rrp6-mediated nuclear retention of the unspliced RNAs and transcriptional down-regulation of the splicing-defective genes
Published in PloS one (12-07-2010)“…Eukaryotic cells have developed surveillance mechanisms to prevent the expression of aberrant transcripts. An early surveillance checkpoint acts at the…”
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Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration
Published in PLoS pathogens (01-10-2016)“…[This corrects the article DOI: 10.1371/journal.ppat.1005860.]…”
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Scaffold attachment factor A (SAF-A) is concentrated in inactive X chromosome territories through its RGG domain
Published in Chromosoma (01-12-2003)“…Female mammalian cells inactivate transcription from one of their X chromosomes to equalize gene expression of X-linked genes between males and females…”
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The exosome associates cotranscriptionally with the nascent pre-mRNP through interactions with heterogeneous nuclear ribonucleoproteins
Published in Molecular biology of the cell (01-08-2009)“…Eukaryotic cells have evolved quality control mechanisms to degrade aberrant mRNA molecules and prevent the synthesis of defective proteins that could be…”
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Analysis of N-acetylglucosamine metabolism in the marine bacterium Pirellula sp. strain 1 by a proteomic approach
Published in Proteomics (Weinheim) (01-06-2002)“…Pirellula sp. strain 1 is a marine bacterium that can grow with the chitin monomer N‐acetylglucosamine as sole source of carbon and nitrogen under aerobic…”
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Molecular-cytogenetic analysis of fragmentation of chromosome 17 in the breast cancer cell line EFM-19
Published in Anticancer research (01-07-2002)“…Because a previous study by conventional cytogenetics had revealed a nullisomy 17 in the breast cancer cell line EFM-19, we analysed that cell line by SKY-FISH…”
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Significant correlation between the breakpoints of rare clonal aberrations in benign solid tumors and the assignment of HMGIY retropseudogenes
Published in Cancer genetics and cytogenetics (01-10-2001)“…Recently, we described a mechanism by which a retropseudogene, during evolution, becomes an exon of a pre-existing active gene. Similar mechanisms may account…”
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