Search Results - "Hel, Z."

Chronic immune activation in common variable immunodeficiency (CVID) is associated with elevated serum levels of soluble CD14 and CD25 but not endotoxaemia by Litzman, J., Nechvatalova, J., Xu, J., Ticha, O., Vlkova, M., Hel, Z.

“…Summary Common variable immunodeficiency (CVID), the most frequent symptomatic immunoglobulin primary immunodeficiency, is associated with chronic T cell…”
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ALVAC-SIV-gag-pol-env-Based Vaccination and Macaque Major Histocompatibility Complex Class I (A01) Delay Simian Immunodeficiency Virus SIVmac-Induced Immunodeficiency by Pal, R, Venzon, D, Letvin, N L, Santra, S, Montefiori, D C, Miller, N R, Tryniszewska, E, Lewis, M G, VanCott, T C, Hirsch, V, Woodward, R, Gibson, A, Grace, M, Dobratz, E, Markham, P D, Hel, Z, Nacsa, J, Klein, M, Tartaglia, J, Franchini, G

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Induction of protective cytotoxic T-cell responses by a B-cell-based cellular vaccine requires stable expression of antigen by Guo, S, Xu, J, Denning, W, Hel, Z

“…B-cell-based cellular vaccines represent a promising approach to active immunotherapy of cancer complementing the use of dendritic cells, especially in…”
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Potentiation of Simian Immunodeficiency Virus (SIV)-Specific CD4+ and CD8+ T Cell Responses by a DNA-SIV and NYVAC-SIV Prime/Boost Regimen by Hel, Zdenek, Tsai, Wen-Po, Thornton, Arthur, Nacsa, Janos, Giuliani, Laura, Tryniszewska, Elzbieta, Poudyal, Monita, Venzon, David, Wang, Xiaochi, Altman, John, Watkins, David I, Lu, Wenhong, von Gegerfelt, Agneta, Felber, Barbara K, Tartaglia, James, Pavlakis, George N, Franchini, Genoveffa

“…T cell-mediated immune responses play an important role in the containment of HIV-1 replication. Therefore, an effective vaccine against HIV-1 should be able…”
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Cervicovaginal Lamina Propria Lymphocytes: Phenotypic Characterization and Their Importance in Cytotoxic T-Lymphocyte Responses to Simian Immunodeficiency Virus SIVmac251 by Stevceva, Liljana, Kelsall, Brian, Nacsa, Janos, Moniuszko, Marcin, Hel, Zdenek, Tryniszewska, Elzbieta, Franchini, Genoveffa

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Impairment of Gag-Specific CD8+ T-Cell Function in Mucosal and Systemic Compartments of Simian Immunodeficiency Virus mac251- and Simian-Human Immunodeficiency Virus KU2-Infected Macaques by Hel, Z, Nacsa, J, Kelsall, B, Tsai, W P, Letvin, N, Parks, R W, Tryniszewska, E, Picker, L, Lewis, M G, Edghill-Smith, Y, Moniuszko, M, Pal, R, Stevceva, L, Altman, J D, Allen, T M, Watkins, D, Torres, J V, Berzofsky, J A, Belyakov, I M, Strober, W, Franchini, G

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An action plan for pan-European defence against new SARS-CoV-2 variants by Priesemann, Viola, Balling, Rudi, Brinkmann, Melanie M, Ciesek, Sandra, Czypionka, Thomas, Eckerle, Isabella, Giordano, Giulia, Hanson, Claudia, Hel, Zdenek, Hotulainen, Pirta, Klimek, Peter, Nassehi, Armin, Peichl, Andreas, Perc, Matjaz, Petelos, Elena, Prainsack, Barbara, Szczurek, Ewa

“…In the case of B.1.1.7, estimates suggest R could increase from 1 to about 1.4 with no change in population behavior.3,4 If true, many countries that have…”
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Two distinct regions in the 3' untranslated region of tumor necrosis factor alpha mRNA form complexes with macrophage proteins by Hel, Zdeněk, Skamene, Emil, Radzioch, Danuta

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Europe must come together to confront omicron

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Effect of hormonal contraception on the function of plasmacytoid dendritic cells and distribution of immune cell populations in the female reproductive tract

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Design and in vivo immunogenicity of a polyvalent vaccine based on SIVmac regulatory genes by Hel, Z, Tryniszewska, E, Tsai, W P, Johnson, J M, Harrod, R, Fullen, J, Kalyanaraman, V S, Altman, J D, McNally, J, Karpova, T, Felber, B K, Tartaglia, J, Franchini, G

“…Most vaccine modalities for human immunodeficiency virus type 1 (HIV-1) tested for immunogenicity and efficacy in the SIVmac (simian immunodeficiency virus)…”
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HIV infection: first battle decides the war by Hel, Zdenek, McGhee, Jerry R., Mestecky, Jiri

“…The traditional view of HIV-1 infection characterized by the slow decline of CD4 + T cells has radically changed in light of recent observations in rhesus…”
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Induction of protective cytotoxic T-cell responses by a B-cell-based cellular vaccine requires stable expression of antigen by Guo, S, Xu, J, Denning, W, Hel, Z

“…B-cell-based cellular vaccines represent a promising approach to active immunotherapy of cancer complementing the use of dendritic cells, especially in…”
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Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4+ and CD8+ T Cell Responses by Hel, Zdenek, Nacsa, Janos, Tryniszewska, Elzbieta, Tsai, Wen-Po, Parks, Robyn Washington, Montefiori, David C, Felber, Barbara K, Tartaglia, James, Pavlakis, George N, Franchini, Genoveffa

“…Macaques infected with the SIV strain SIVmac251 develop a disease closely resembling human AIDS characterized by high viremia, progressive loss of CD4(+) T…”
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Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques by Belyakov, Igor M, Berzofsky, Jay A, Hel, Zdenek, Kelsall, Brian, Kuznetsov, Vladimir A, Ahlers, Jeffrey D, Nacsa, Janos, Watkins, David I, Allen, Todd M, Sette, Alessandro, Altman, John, Woodward, Ruth, Markham, Phillip D, Clements, John D, Franchini, Genoveffa, Strober, Warren

“…Given the mucosal transmission of HIV-1, we compared whether a mucosal vaccine could induce mucosal cytotoxic T lymphocytes (CTLs) and protect rhesus macaques…”
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Fragile X-related Protein FXR1P Regulates Proinflammatory Cytokine Tumor Necrosis Factor Expression at the Post-transcriptional Level by Garnon, James, Lachance, Claude, Di Marco, Sergio, Hel, Zdenek, Marion, Dominique, Ruiz, Maria C., Newkirk, Marianna M., Khandjian, Edouard W., Radzioch, Danuta

“…Tumor necrosis factor (TNF) is regulated post-transcriptionally by the AU-rich element (ARE) within the 3′-untranslated region of its mRNA. This regulation…”
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Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques by Hel, Z, Venzon, D, Poudyal, M, Tsai, W P, Giuliani, L, Woodward, R, Chougnet, C, Shearer, G, Altman, J D, Watkins, D, Bischofberger, N, Abimiku, A, Markham, P, Tartaglia, J, Franchini, G

“…Prolonged antiretroviral therapy (ART) is not likely to eradicate human immunodeficiency virus type I (HIV-I) infection. Here we explore the effect of…”
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Improved Vaccine Protection from Simian AIDS by the Addition of Nonstructural Simian Immunodeficiency Virus Genes by Hel, Zdenek, Tsai, Wen-Po, Tryniszewska, Elzbieta, Nacsa, Janos, Markham, Phillip D, Lewis, Mark G, Pavlakis, George N, Felber, Barbara K, Tartaglia, Jim, Franchini, Genoveffa

“…An HIV-1 vaccine able to induce broad CD4+ and CD8+ T cell responses may provide long-term control of viral replication. In this study we directly assess the…”
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Systemic Immunization with an ALVAC-HIV-1/Protein Boost Vaccine Strategy Protects Rhesus Macaques from CD4+ T-Cell Loss and Reduces both Systemic and Mucosal Simian-Human Immunodeficiency Virus SHIVKU2 RNA Levels by PAL, Ranajit, VENZON, David, MONIUSZKO, Marcin, HEL, Zdenek, BELYAKOV, Igor M, BERZOFSKY, Jay A, PARKS, Robyn Washington, MARKHAM, Phillip D, LETVIN, Norman L, TARTAGLIA, Jim, FRANCHINI, Genoveffa, SANTRA, Sampa, KALYANARAMAN, Vaniambadi S, MONTEFIORI, David C, HOCKER, Lindsey, HUDACIK, Lauren, ROSE, Nicolas, NACSA, Janos, EDGHILL-SMITH, Yvette

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Polymorphism in the 3'-untranslated region of TNF alpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNF alpha mRNA by Di Marco, S, Hel, Z, Lachance, C, Furneaux, H, Radzioch, D

“…Tumor necrosis factor alpha (TNF alpha ) acts as a beneficial mediator in the process of host defence. In recent years major interest has focused on the…”
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