Search Results - "Hekster, Yechiel A."

Adherence Rates and Associations with Nonadherence in Patients with Rheumatoid Arthritis Using Disease Modifying Antirheumatic Drugs by VAN DEN BEMT, Bart J. F, VAN DEN HOOGEN, Frank H. J, BENRAAD, Bart, HEKSTER, Yechiel A, VAN RIEL, Piet L. C. M, VAN LANKVELD, Wim

“…Objective. Nonadherence in patients with rheumatoid arthritis (RA) using disease modifying antirheumatic drugs (DMARD) may result in unnecessarily high levels…”
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Ephedrine treatment for autoimmune myasthenia gravis by Lipka, Alexander F., MD, Vrinten, Charlotte, MSc, van Zwet, Erik W, PhD, Schimmel, Kirsten JM, PhD, Cornel, Martina C, MD, PhD, Kuijpers, Marja R, Hekster, Yechiel A, PhD, Weinreich, Stephanie S, PhD, Verschuuren, Jan JGM, MD, PhD

“…Highlights • Anecdotal evidence suggests a symptomatic effect of ephedrine in myasthenia gravis. • This series of randomized controlled n-of-1 trials compared…”
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The impact of side effects on long-term retention in three new antiepileptic drugs by Bootsma, Hans P, Ricker, Lukas, Hekster, Yechiel A, Hulsman, Jacques, Lambrechts, Danielle, Majoie, Marian, Schellekens, Ad, de Krom, Marc, Aldenkamp, Albert P

“…Abstract Objective To determine long-term retention, percentage of patients withdrawing because of adverse events, percentage of patients achieving seizure…”
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Aggregated N-of-1 trials for unlicensed medicines for small populations: an assessment of a trial with ephedrine for myasthenia gravis by Weinreich, Stephanie S, Vrinten, Charlotte, Kuijpers, Marja R, Lipka, Alexander F, Schimmel, Kirsten J M, van Zwet, Erik W, Gispen-de Wied, Christine, Hekster, Yechiel A, Verschuuren, Jan J G M, Cornel, Martina C

“…Inexpensive medicines with a long history of use may currently be prescribed off-label for rare indications. Reimbursement is at the discretion of health…”
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Selection of Antiepileptic Drug Polytherapy Based on Mechanisms of Action: The Evidence Reviewed by Deckers, Charles L. P., Czuczwar, Stanislaw J., Hekster, Yechiel A., Kewser, Antoine, Kubova, Hana, Meinardi, Harry, Patsalos, Philip N., Renier, Willy O., Rijn, Clementina M.

“…Purpose: When monotherapy with antiepileptic drugs (AEDs) fails, combination therapy is tried in an attempt to improve effectiveness by improving efficacy,…”
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Anti-infliximab antibodies are already detectable in most patients with rheumatoid arthritis halfway through an infusioncycle: an open-label pharmacokinetic cohort study by van den Bemt, Bart J.F, den Broeder, Alfons A, Wolbink, G.J, Hekster, Yechiel A, van Riel, Piet L.C.M, Benraad, Bart, van den Hoogen, Frank H.J

“…Background This study in patients with rheumatoid arthritis (RA) treated with infliximab describes prospectively the course of (anti)infliximab levels within…”
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The accuracy, precision and sustainability of different techniques for tablet subdivision: Breaking by hand and the use of tablet splitters or a kitchen knife by van Riet-Nales, Diana A., Doeve, Myrthe E., Nicia, Agnes E., Teerenstra, Steven, Notenboom, Kim, Hekster, Yechiel A., van den Bemt, Bart J.F.

“…[Display omitted] Tablets are frequently subdivided to lower the dose, to facilitate swallowing by e.g. children or older people or to save costs. Splitting…”
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Assessment of Drug-Drug Interactions Between Tenofovir Disoproxil Fumarate and the Nonnucleoside Reverse Transcriptase Inhibitors Nevirapine and Efavirenz in HIV-Infected Patients by Droste, Jacqueline A. H, Kearney, Brian P, Hekster, Yechiel A, Burger, David M

“…BACKGROUND:Tenofovir disoproxil fumarate (DF) has been studied in combination with efavirenz in healthy volunteers and no interaction was found. No data are…”
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Analysis of variation in plasma concentrations of nelfinavir and its active metabolite M8 in HIV-positive patients by BAEDE-VAN DIJK, Patricia A, HUGEN, Patricia W. H, VERWEIJ-VAN WISSEN, Corrien P. W. G. M, KOOPMANS, Peter P, BURGER, David M, HEKSTER, Yechiel A

“…To characterize sources of variation in plasma concentrations of nelfinavir and its active metabolite M8 and to evaluate the use of therapeutic drug monitoring…”
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Controlled release of morphine from a poloxamer 407 gel by Jansen, Mark M.P.M., Verzijl, Jacques M., Burger, David M., Hekster, Yechiel A.

“…[Display omitted] •Measurement of in vitro release characteristics of morphine from a P407 based gel.•Measurement was done with a dissolution cell.•The…”
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International Interlaboratory Quality Control Program for Measurement of Antiretroviral Drugs in Plasma by AARNOUTSE, Rob E, WISSEN, Corrien P. W. G. M. Verweij-Va, VAN EWIJK-BENEKEN KOLMER, Eleonora W. J, WUIS, Eveline W, KOOPMANS, Peter P, HEKSTER, Yechiel A, BURGER, David M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The combined use of disease activity and infliximab serum trough concentrations for early prediction of (non‐)response to infliximab in rheumatoid arthritis by Bemt, Bart J. F., Broeder, Alfons A., Wolbink, Gert‐Jan, Maas, Aatke, Hekster, Yechiel A., Riel, Piet L. C. M., Benraad, H. Bart, Hoogen, Frank H. J.

“…Aim Early prediction of (non‐)response to infliximab therapy can improve therapeutic benefit by avoiding unnecessary periods of high disease activity during…”
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A Cost-Effectiveness Decision Model for Antiepileptic Drug Treatment in Newly Diagnosed Epilepsy Patients by Knoester, Pieter D., PharmD, PhD, Deckers, Charles L.P., MD, PhD, Termeer, Eveline H., MSc, Boendermaker, Arjo J., MSc, Kotsopoulos, Irene A.W., MD, PhD, de Krom, Marc C.T.F.M., MD, PhD, Keyser, Toine, MD, PhD, Renier, Willy O., MD, PhD, Hekster, Yechiel A., PhD, Severens, Hans L., PhD

“…Abstract Objectives To establish cost-effectiveness of antiepileptic drug (AED) treatment strategies of newly diagnosed patients with epilepsy. Methods A…”
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Authors’ response to the letter from Kalleian Eserian et al by van Riet-Nales, Diana A., Doeve, Myrthe E., Nicia, Agnes E., Teerenstra, Steven, Notenboom, Kim, Hekster, Yechiel A., van den Bemt, Bart J.F.

“…[Display omitted] This letter is a response to the comments of Kalleian Eserian et al. on our study relating to the accuracy, precision and sustainability of…”
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Therapeutic drug monitoring: An aid to optimising response to antiretroviral drugs? by AARNOUTSE, Rob E, SCHAPIRO, Jonathan M, BOUCHER, Charles A. B, HEKSTER, Yechiel A, BURGER, David M

“…Therapeutic drug monitoring (TDM) has been proposed as a means to optimise response to highly active antiretroviral therapy (HAART) in HIV infection. Protease…”
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Ephedrine as add-on therapy for patients with myasthenia gravis: protocol for a series of randomised, placebo-controlled n-of-1 trials by Vrinten, Charlotte, Lipka, Alexander F, van Zwet, Erik W, Schimmel, Kirsten J M, Cornel, Martina C, Kuijpers, Marja R, Hekster, Yechiel A, Weinreich, Stephanie S, Verschuuren, Jan J G M

“…IntroductionMyasthenia gravis (MG), a rare neuromuscular disease, is often initially treated using acetylcholinesterase inhibitors. Patients who do not respond…”
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Assessment of adherence to HIV protease inhibitors: Comparison and combination of various methods, including MEMS (electronic monitoring), patient and nurse report, and therapeutic drug monitoring by HUGEN, Patricia W. H, LANGEBEEK, Nienke, BURGER, David M, ZOMER, Bert, VAN LEUSEN, Rob, SCHUURMAN, Rob, KOOPMANS, Peter P, HEKSTER, Yechiel A

“…Adherence to protease inhibitor-containing antiretroviral therapy is crucial, but difficult to measure. To compare and combine various methods of measuring…”
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Evaluation of antiretroviral drug measurements by an interlaboratory quality control program by DROSTE, Jacqueline A. H, AARNOUTSE, Rob E, KOOPMANS, Peter P, HEKSTER, Yechiel A, BURGER, David M

“…Since 1999 an ongoing international interlaboratory quality control program has analyzed antiretroviral drugs in plasma. Results of the third round of this…”
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Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers by Aarnoutse, Rob E, Kleinnijenhuis, Johanneke, Koopmans, Peter P, Touw, Daan J, Wieling, Jaap, Hekster, Yechiel A, Burger, David M

“…Objective In the treatment of human immunodeficiency virus infection, the protease inhibitor ritonavir is used in a low dose (100 mg twice daily) to inhibit…”
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Monotherapy versus Polytherapy for Epilepsy: A Multicenter Double‐Blind Randomized Study by Deckers, Charles L. P., Hekster, Yechiel A., Keyser, Antoine, Van Lier, Henk J. J., Meinardi, Harry, Renier, Willy O.

“…Purpose: Monotherapy has been the gold standard in epilepsy treatment for the last 20 years, partly because of the reputation for increased toxicity of…”
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