Search Results - "Hekster, Y.A."

Simultaneous determination of the HIV-protease inhibitors indinavir, nelfinavir, saquinavir and ritonavir in human plasma by reversed-phase high-performance liquid chromatography by Hugen, P.W.H., Verweij-van Wissen, C.P.W.G.M., Burger, D.M., Wuis, E.W., Koopmans, P.P., Hekster, Y.A.

“…A sensitive high-performance liquid chromatographic method has been developed for the simultaneous determination of the four licensed HIV-protease inhibitors…”
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Effectiveness of lamotrigine in clinical practice: Results of a retrospective population-based study by Knoester, P.D., Keyser, A., Renier, W.O., Egberts, A.C.G., Hekster, Y.A., Deckers, C.L.P.

“…Evaluation of the effectiveness of lamotrigine in a population-based cohort of epilepsy patients. Medical charts of 360 patients treated in 37 centres in The…”
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Cost-effectiveness of add-on lamotrigine therapy in clinical practice by Knoester, P.D., Boendermaker, A.J., Egberts, A.C.G., Hekster, Y.A., Keyser, A., Severens, J.L., Renier, W.O., Deckers, C.L.P.

“…This retrospective study addresses the cost-effectiveness of add-on therapy with lamotrigine in clinical practice. Two years’ observational data of 165…”
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Characteristics of Topics in Pharmacovigilance in The Netherlands by Meyboom, R.H.B., Gribnau, F.W.J., Hekster, Y.A., de Koning, G.H.P., Egberts, A.C.G.

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Off-Label Use of Drugs in Pain Medicine and Palliative Care: An Algorithm for the Assessment of its Safe and Legal Prescription by Verhagen, Constans C. A. H. H. V. M., Niezink, Anne G. H., Engels, Yvonne Y, Hekster, Yechiel Y. A., Doornebal, Joan J., Vissers, Kris C. P.

“…▪   Off‐label medication use is common practice, particularly in difficult to treat patients who have already tried commonly accepted medication…”
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Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres by Lammers, M W, Wijsman, D J, Hekster, Y A, Keyser, A, Renier, W O, Meinardi, H, van Lier, H

“…To test the feasibility of comparing epilepsy treatment policies and outcome, a secondary and a tertiary epilepsy care facility have been audited in a previous…”
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High-performance liquid chromatography of HIV protease inhibitors in human biological matrices by Aarnoutse, R.E, Verweij-van Wissen, C.P.W.G.M, Underberg, W.J.M, Kleinnijenhuis, J, Hekster, Y.A, Burger, D.M

“…Methods for HPLC analysis of protease inhibitors (PIs) in human biological matrices were reviewed. Assays have been developed for analysis of single PIs or for…”
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Novel oxidative pathways of sulphapyridine and sulphadiazine by the turtle Pseudemys scripta elegans by Vree, T B, Vree, J B, Beneken Kolmer, E W, Hekster, Y A

“…The sulphonamides sulphapyridine and sulphadiazine show novel hydroxy metabolites in the turtle Pseudemys scripta elegans. In the excreta of the turtles the…”
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Determination of nevirapine, an HIV-1 non-nucleoside reverse transcriptase inhibitor, in human plasma by reversed-phase high-performance liquid chromatography by Hollanders, R.M.F, van Ewijk-Beneken Kolmer, E.W.J, Burger, D.M, Wuis, E.W, Koopmans, P.P, Hekster, Y.A

“…A sensitive and rapid high-performance liquid chromatography method has been developed to measure the levels of the HIV-1 non-nucleoside reverse transcriptase…”
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Rapid determination of amoxycillin (clamoxyl) and ampicillin (penbritin) in body fluids of many by means of high-performance liquid chromatography by Vree, T B, Hekster, Y A, Baars, A M, Van der Kleijn, E

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Determination of trimethoprim and sulfamethoxazole (co-trimoxazole) in body fluids of man by means of high-performance liquid chromatography by Vree, T B, Hekster, Y A, Baars, A M, Damsma, J E, Kleijin, E V

“…A high-performance liquid chromatographic method for the determination of trimethoprim, sulfamethoxazole and its metabolite and a series of structurally…”
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Pharmacokinetics of theophylline and its metabolites in a patient undergoing continuous ambulatory peritoneal dialysis by VREE, T. B, MARTEA, M, TIGGELER, R. G. W. L, HEKSTER, Y. A, HAFKENSCHEID, J. C. M

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Determination of indinavir, an HIV-protease inhibitor, in human plasma by reversed-phase high-performance liquid chromatography by Burger, D.M, de Graaff, M, Wuis, E.W, Koopmans, P.P, Hekster, Y.A

“…A sensitive high-performance liquid chromatographic assay has been developed to determine the concentrations of the HIV-protease inhibitor indinavir in human…”
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O-Dealkylation and N4-acetylation of sulpha-2-monomethoxine by the turtle Pseudemys scripta elegans by Vree, T B, Vree, M L, Beneken Kolmer, E W, Hekster, Y A, Shimoda, M, Ono, M, Miura, T

“…Sulpha-2-monomethoxine is N4-acetylated to an extent of 12% of the dose by Pseudemys scripta elegans; 48% is excreted unchanged. No O-dealkylation of the…”
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O-demethylation and N4-acetylation of sulphadimethoxine by the turtle Pseudemys scripta elegans by Vree, T B, Vree, J B, Beneken Kolmer, N, Hekster, Y A, Shimoda, M, Nouws, J F, Yoshioka, T, Hoji, K

“…After an oral dose of 350 mg of sulphadimethoxine, the turtle Pseudemys scripta elegans O-dealkylates sulphadimethoxine at the 2- and 6-position at 38% and 19%…”
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Pefloxacin-aminophylline interaction by Dirksen, M S, Hekster, Y A, Waas, R J, Boerema, J B

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o-Dealkylation and acetylation of sulfamethomidine by the snail Cepaea hortensis by Vree, T B, Vree, M L, Beneken Kolmer, E W, Ross, M E, Hekster, Y A, Shimoda, M, Nouws, J F

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Oxidation and O-dealkylation of sulphamonomethoxine by the turtle Pseudemys scripta elegans by Vree, T B, Vree, J B, Beneken Kolmer, N, Hekster, Y A, Shimoda, M, Nouws, J F, Yoshioka, T, Hoji, K

“…Sulphamonomethoxine is O-demethylated at the 6 position and oxidised at the 2 position of the pyrimidine substituent by Pseudemys scripta elegans. No…”
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N-oxidation, O-demethylation, and excretion of trimethoprim by the turtle Pseudemys scripta elegans by Vree, T B, Vree, J B, Kolmer, E B, Hekster, Y A, Nouws, J F, Shimoda, M

“…Trimethoprim was excreted within one hour after being given orally to the turtle Pseudemys scripta elegans. No O-demethylated or N-oxide metabolites were…”
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Lack of oxidative pathways in the metabolism of sulphisomidine by the turtle Pseudemys scripta elegans by Vree, T B, Vree, J B, De Jonge, P A, Plaum, M J, Verwey, C P, Hekster, Y A, Shimoda, M, Nouws, J F

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