Search Results - "Hejchman, Elżbieta"
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Design, synthesis, and biological activity of Schiff bases bearing salicyl and 7-hydroxycoumarinyl moieties
Published in Monatshefte für Chemie (01-02-2019)“…18 (11 novel) Schiff bases, derivatives of salicylaldehyde, 2-hydroxyacetophenone, and 6-acetyl-, 8-acetyl-, and 8-formyl-7-hydroxy-4-methylcoumarin were…”
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2
Synthesis and antifungal activity of derivatives of 2- and 3-benzofurancarboxylic acids
Published in The Journal of pharmacology and experimental therapeutics (01-11-2012)“…We found that amiodarone has potent antifungal activity against a broad range of fungi, potentially defining a new class of antimycotics. Investigations into…”
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3
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure
Published in Experimental parasitology (01-06-2018)“…Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two…”
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4
Synthesis and pharmacological activity of O-aminoalkyl derivatives of 7-hydroxycoumarin
Published in European journal of medicinal chemistry (01-06-2011)“…A series of novel O-aminoalkyl substituted 7-hydroxycoumarins were synthesized and evaluated for antibacterial and anticancer toxicity. Two different synthetic…”
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5
Synthesis, structural studies and biological activity of new Cu(II) complexes with acetyl derivatives of 7-hydroxy-4-methylcoumarin
Published in Journal of inorganic biochemistry (01-04-2015)“…The new Cu(II) complexes with 6-acetyl-7-hydroxy-4-methylcoumarin (HL1) and 8-acetyl-7-hydroxy-4-methylcoumarin (HL2) have been obtained by the electrochemical…”
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6
Synthesis and anticancer activity of 7-hydroxycoumarinyl gallates
Published in Pharmacological reports (01-04-2015)“…The search for anti-cancer agents includes naturally occurring substances and theirs modifications. Therefore we invented and designed compounds that represent…”
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7
Microwave-assisted preparation, structural characterization, lipophilicity, and anti-cancer assay of some hydroxycoumarin derivatives
Published in Monatshefte für Chemie (01-01-2015)“…A new series of hydroxycoumarin derivatives has been synthesized using conventional synthesis. The syntheses were accelerated by microwave assistance. Yields…”
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8
Microwave-assisted preparation and antimicrobial activity of O-alkylamino benzofurancarboxylates
Published in Monatshefte für Chemie (2013)“…A series of derivatives of 2 and 3-benzofurancarboxylates were synthesized under microwave-assisted conditions. Their in-vitro antimicrobial properties were…”
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9
Conventional and Microwave-Assisted Syntheses and Solid-State Structure of New Coumarins and Angelicins
Published in Synthetic communications (15-08-2011)“…New derivatives of coumarin and angelicin, 8-acetyl-7-cyanomethoxy-4-methyl-chromen-2-one (1), 8-acetyl-7-ethoxycarbonylmethoxy-4-methyl-chromen-2-one (2),…”
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10
Microwave-assisted synthesis of derivatives of khellinone under phase-transfer catalytic conditions
Published in Monatshefte für Chemie (01-11-2008)“…The microwave-assisted synthesis of four new 5-acetyl-4,7-dimethoxy-6-hydroxybenzofuran (khellinone) analogs is described. The structures of the obtained…”
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11
Synthesis and structural characterization of derivatives of 2- and 3-benzo[b]furan carboxylic acids with potential cytotoxic activity
Published in Farmaco (Società chimica italiana : 1989) (01-06-2005)“…Derivatives of 2- and 3-benzo[b]furancarboxylic acids were prepared and evaluated for their cytotoxic potential in the National Cancer Institute, Bethesda,…”
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12
Synthesis and Structural Characterization of Aminoalkanol Derivatives of 2,3-Dihydro-2,2-dimethyl-7-benzofuranol with an Expected β-Adrenolytic and / or Anxiolytic Activity
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01-03-2002)“…A series of fifteen new N-substituted derivatives of 2,3-dihydro-2,2-dimethyl-7-benzofuranol have been prepared and studied by IR and H NMR spectroscopy. In…”
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13
Solid state structure of new 5-[2-(N,N-diethylamino)ethoxy]-4,7-dimethylcoumarins by X-ray and 13C CP/MAS NMR
Published in Journal of molecular structure (15-05-2015)“…[Display omitted] •We report microwave-assisted synthesis of new hydroxycoumarin derivatives.•The structures of new compounds were studied with X-ray…”
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14
Antiproliferative effect of a benzofuran derivate based on the structure of amiodarone on Leishmania donovani affecting mitochondria, acidocalcisomes and intracellular Ca2+ homeostasis
Published in Parasitology international (01-06-2019)“…Leishmaniasis is a parasitic disease representing an important problem of public health. Visceral leishmaniasis, resulting from infection with Leishmania…”
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15
Antiproliferative effect of a benzofuran derivate based on the structure of amiodarone on Leishmania donovani affecting mitochondria, acidocalcisomes and intracellular Ca 2+ homeostasis
Published in Parasitology international (19-02-2019)“…Leishmaniasis is a parasitic disease representing an important problem of public health. Visceral leishmaniasis, resulting from infection with Leishmania…”
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16
Solid-state structure of O-aminoalkyl derivatives of 7-hydroxy-4-methylcoumarin by 13C CP/MAS NMR and X-ray diffraction methods
Published in Journal of molecular structure (2011)“…► 13C CP/MAS NMR spectra of O-aminoalkylcoumarins 1–3 indicate one conformer in solid-state. ► Acetyl group at C6 atom is located in the plane of coumarin…”
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17
Solid state structure by X-ray and 13C CP/MAS NMR of new 7-[2-( N,N-diisopropylamino)ethoxy]coumarins
Published in Journal of molecular structure (01-07-2009)“…7-[2-( N,N-Diisopropylamino)ethoxy]coumarin ( 1) and 7-[2-( N,N-diisopropylamino)ethoxy]-4-methylcoumarin ( 2) were synthesized in a traditional way and by…”
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18
Synthesis and Cytotoxicity of Water-Soluble Ambrosin Prodrug Candidates
Published in Journal of medicinal chemistry (01-08-1995)“…The potential therapeutic application of the naturally occurring, cytotoxic pseudoguaianolide sesquiterpene lactone ambrosin is limited by its aqueous…”
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19
Solid-state structure of O-aminoalkyl derivatives of 7-hydroxy-4-methylcoumarin by super(13C CP/MAS NMR and X-ray diffraction methods)
Published in Journal of molecular structure (13-07-2011)“…Solid-state structures of three new coumarins: 7-[2-(N-benzyl-N-methylamino)ethoxy]-4-methylcoumarin ( 1),…”
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20
Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XVI. Derivatives of 1-acetoxy-7,7-dimethylbicyclo[2.2.2]octan-5-one-2,3-dicarboximide
Published in Acta Poloniae pharmaceutica (01-01-2003)“…The preparation of a potential anxiety-relieving compounds…”
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