Search Results - "Heitz, U."

The Gastroenteropancreatic Neuroendocrine Cell System and Its Tumors: The WHO Classification by KLÖPPEL, GÜNTER, PERREN, AUREL, HEITZ, PHILIPP U.

“…: Although well established in medical terminology, the term carcinoid is no longer adequate to cover the entire morphological and biological spectrum of…”
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Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and functional activity by Garbrecht, Nele, Anlauf, Martin, Schmitt, Anja, Henopp, Tobias, Sipos, Bence, Raffel, Andreas, Eisenberger, Claus F, Knoefel, Wolfram T, Pavel, Marianne, Fottner, Christian, Musholt, Thomas J, Rinke, Anja, Arnold, Rudolf, Berndt, Uta, Plöckinger, Ursula, Wiedenmann, Bertram, Moch, Holger, Heitz, Philipp U, Komminoth, Paul, Perren, Aurel, Klöppel, Günter

“…Somatostatin-producing neuroendocrine tumors (SOM-NETs) of the duodenum and pancreas appear to be heterogeneous. To determine their clinicopathological…”
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Sporadic versus hereditary gastrinomas of the duodenum and pancreas： Distinct clinico-pathological and epidemiological features by Anlauf, Martin, Garbrecht, Nele, Henopp, Tobias, Schmitt, Anja, Schlenger, Regina, Raffel, Andreas, Krausch, Markus, Gimm, Oliver, Eisenberger, Claus F, Knoefel, Wolfram T, Dralle, Henning, Komminoth, Paul, Heitz, Philipp U, Perren, Aurel, Klöppel, Gunter

“…Gastrinomas are defined as gastrin secreting tumors that are associated with Zollinger-Ellison syndrome （ZES）. ZES is characterized by elevated fasting gastrin…”
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WHO 2004 criteria and CK19 are reliable prognostic markers in pancreatic endocrine tumors by SCHMITT, Anja M, ANLAUF, Martin, HEITZ, Philipp U, KLOEPPEL, Guenter, KOMMINOTH, Paul, PERREN, Aurel, ROUSSON, Valentin, SCHMID, Sonja, KOFLER, Andreas, RINIKER, Florian, BAUERSFELD, Juliane, BARGHORN, Andre, PROBST-HENSCH, Nicole M, MOCH, Holger

“…It is difficult to predict the biologic behavior of pancreatic endocrine tumors in absence of metastases or invasion into adjacent organs. The World Health…”
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VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors by Schmitt, A M, Schmid, S, Rudolph, T, Anlauf, M, Prinz, C, Klöppel, G, Moch, H, Heitz, P U, Komminoth, P, Perren, A

“…A small subset of familial pancreatic endocrine tumors (PET) arises in patients with von Hippel–Lindau syndrome and these tumors may have an adverse outcome…”
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Mutation and Expression Analyses Reveal Differential Subcellular Compartmentalization of PTEN in Endocrine Pancreatic Tumors Compared to Normal Islet Cells by Perren, Aurel, Komminoth, Paul, Saremaslani, Parvin, Matter, Claudia, Feurer, Seraina, Lees, Jacqueline A., Heitz, Philipp U., Eng, Charis

“…The pathogenesis of sporadic endocrine pancreatic tumors (EPTs) is still primarily unknown. Comparative genomic hybridization studies revealed loss of 10q in a…”
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Microadenomatosis of the endocrine pancreas in patients with and without the multiple endocrine neoplasia type 1 syndrome by ANLAUF, Martin, SCHLENGER, Regina, COUVELARD, Anne, KOMMINOTH, Paul, HEITZ, Philipp U, KLOPPEL, Günter, PERREN, Aurel, BAUERSFELD, Juliane, KOCH, Christian A, DRALLE, Henning, RAFFEL, Andreas, KNOEFEL, Wolfram T, WEIHE, Eberhard, RUSZNIEWSKI, Philippe

“…It has been suggested that microadenomatosis of the endocrine pancreas is a hallmark of the multiple endocrine neoplasia type 1 syndrome (MEN1). This study…”
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Course of alcoholic chronic pancreatitis: A prospective clinicomorphological long-term study by Ammann, RW, Heitz, PU, Kloppel, G

“…BACKGROUND & AIMS: The pathogenesis of alcoholic chronic pancreatitis and its relationship to alcoholic acute pancreatitis are debated. According to our recent…”
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IGFII and MIB1 immunohistochemistry is helpful for the differentiation of benign from malignant adrenocortical tumours by Schmitt, A, Saremaslani, P, Schmid, S, Rousson, V, Montani, M, Schmid, D M, Heitz, Ph U, Komminoth, P, Perren, A

“…Aims:  The differentiation of adrenocortical carcinomas from adenomas may be difficult based on morphology alone. Differential expression of insulin‐like…”
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Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions by Anlauf, M, Perren, A, Henopp, T, Rudolf, T, Garbrecht, N, Schmitt, A, Raffel, A, Gimm, O, Weihe, E, Knoefel, W T, Dralle, H, Heitz, Ph U, Komminoth, P, Klöppel, G

“…Background: Patients with a multiple endocrine neoplasia type 1 (MEN1)-associated Zollinger–Ellison syndrome (ZES) show multifocal duodenal gastrinomas and…”
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Mutations and Allelic Deletions of the MEN1 Gene Are Associated with a Subset of Sporadic Endocrine Pancreatic and Neuroendocrine Tumors and Not Restricted to Foregut Neoplasms by Görtz, Birgit, Roth, Jürgen, Krähenmann, Akiko, de Krijger, Ronald R., Muletta-Feurer, Seraina, Rütimann, Katrin, Saremaslani, Parvin, Speel, Ernst J.M., Heitz, Philipp U., Komminoth, Paul

“…Endocrine pancreatic tumors (EPT) and neuroendocrine tumors (NET) occur sporadically and rarely in association with multiple endocrine neoplasia type 1 (MEN1)…”
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Persistent hyperinsulinemic hypoglycemia in 15 adults with diffuse nesidioblastosis: diagnostic criteria, incidence, and characterization of beta-cell changes by Anlauf, Martin, Wieben, Daniel, Perren, Aurel, Sipos, Bence, Komminoth, Paul, Raffel, Andreas, Kruse, Marie L, Fottner, Christian, Knoefel, Wolfram T, Mönig, Heiner, Heitz, Philipp U, Klöppel, Günter

“…Persistent hyperinsulinemic hypoglycemia (PHH) in adults that is not caused by an insulinoma is a rare and not well-characterized disease that has been named…”
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Combined comparative genomic hybridization and genomic microarray for detection of gene amplifications in pulmonary artery intimal sarcomas and adrenocortical tumors by Zhao, Jianming, Roth, Jürgen, Bode-Lesniewska, Beata, Pfaltz, Madeleine, Heitz, Philipp U., Komminoth, Paul

“…Identification of gene amplifications in human tumors is important for the understanding of tumorigenesis and may lead to discovery of diagnostic and…”
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Genetic Differences in Endocrine Pancreatic Tumor Subtypes Detected by Comparative Genomic Hybridization by Speel, Ernst J.M., Richter, Jan, Moch, Holger, Egenter, Carole, Saremaslani, Parvin, Rütimann, Katrin, Zhao, Jianming, Barghorn, André, Roth, Jürgen, Heitz, Philipp U., Komminoth, Paul

“…The molecular pathogenesis as well as histogenesis of endocrine pancreatic tumors (EPTs) is not well understood, and the clinical behavior of EPTs is difficult…”
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Precursor Lesions in Patients With Multiple Endocrine Neoplasia Type 1--Associated Duodenal Gastrinomas by Anlauf, Martin, Perren, Aurel, Meyer, Cora Lu, Schmid, Sonja, Saremaslani, Parvin, Kruse, Marie L., Weihe, Eberhard, Komminoth, Paul, Heitz, Philipp U., Klöppel, Günter

“…Background & Aims: The identification of precursor lesions has a great impact on the understanding of tumorigenesis. Precursor lesions of endocrine tumors are…”
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Revised classification of neuroendocrine tumours of the lung, pancreas and gut by CAPELLA, C, HEITZ, P. U, HÖFLER, H, SOLCIA, E, KLÖPPEL, G

“…In this article new classifications of the neuroendocrine tumours of the lung, pancreas and gut are proposed. These classifications use a common frame work and…”
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Preferential HER-2/neu overexpression and/or amplification in aggressive histological subtypes of invasive breast cancer by Varga, Z, Zhao, J, Öhlschlegel, C, Odermatt, B, Heitz, P U

“…Aims:  To investigate whether alterations of the HER2 gene occur more frequently in histologically unfavourable subtypes of invasive breast cancer. Methods: …”
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Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9Q34 is an early event in insulinomas by SPEEL, Ernst J. M, SCHEIDWEILER, Alexander F, JIANMING ZHAO, MATTER, Claudia, SAREMASLANI, Parvin, ROTH, Jürgen, HEITZ, Philipp U, KOMMINOTH, Paul

“…The malignant potential among endocrine pancreatic tumors (EPTs) varies greatly and can frequently not be predicted using histopathological parameters. Thus,…”
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Lymph node surgery in papillary thyroid carcinoma by Gemsenjäger, Ernst, Perren, Aurel, Seifert, Burkhardt, Schüler, Georges, Schweizer, Ingrid, Heitz, Philipp U

“…The impact of nodal disease remains controversial in papillary thyroid carcinoma (PTC). One surgeon treated 159 unselected patients, who were followed up for 1…”
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Absence of BRAF Gene Mutations Differentiates Spitz Nevi from Malignant Melanoma by Mihic-Probst, Daniela, Perren, Aurel, Schmid, Sonja, Saremaslani, Parvin, Komminoth, Paul, Heitz, Philipp U

“…Background: Distinction of Spitz nevus from malignant melanoma is sometimes difficult on the basis of conventional histology. A high rate of BRAF gene…”
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