Search Results - "Heiss, Jonathan A."

Identifying mislabeled and contaminated DNA methylation microarray data: an extended quality control toolset with examples from GEO by Heiss, Jonathan A, Just, Allan C

“…Mislabeled, contaminated or poorly performing samples can threaten power in methylation microarray analyses or even result in spurious associations. We…”
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Improved filtering of DNA methylation microarray data by detection p values and its impact on downstream analyses by Heiss, Jonathan A, Just, Allan C

“…DNA methylation microarrays are popular for epigenome-wide association studies (EWAS), but spurious values complicate downstream analysis and threaten…”
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Saliva cell type DNA methylation reference panel for epidemiological studies in children by Middleton, Lauren Y. M., Dou, John, Fisher, Jonah, Heiss, Jonathan A., Nguyen, Vy K., Just, Allan C., Faul, Jessica, Ware, Erin B., Mitchell, Colter, Colacino, Justin A., M. Bakulski, Kelly

“…Saliva is a widely used biological sample, especially in pediatric research, containing a heterogenous mixture of immune and epithelial cells. Associations of…”
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Battle of epigenetic proportions: comparing Illumina's EPIC methylation microarrays and TruSeq targeted bisulfite sequencing by Heiss, Jonathan A., Brennan, Kasey J., Baccarelli, Andrea A., Téllez-Rojo, Martha M., Estrada-Gutiérrez, Guadalupe, Wright, Robert O., Just, Allan C.

“…DNA methylation microarrays have been the platform of choice for epigenome-wide association studies in epidemiology, but declining costs have rendered targeted…”
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Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium by Ronkainen, Justiina, Heiskala, Anni, Vehmeijer, Florianne O.L., Lowry, Estelle, Caramaschi, Doretta, Estrada Gutierrez, Guadalupe, Heiss, Jonathan A., Hummel, Nadine, Keikkala, Elina, Kvist, Tuomas, Kupsco, Allison, Melton, Phillip E., Pesce, Giancarlo, Soomro, Munawar H., Vives-Usano, Marta, Baiz, Nour, Binder, Elisabeth, Czamara, Darina, Guxens, Mònica, Mustaniemi, Sanna, London, Stephanie J., Rauschert, Sebastian, Vääräsmäki, Marja, Vrijheid, Martine, Ziegler, Anette-G., Annesi-Maesano, Isabella, Bustamante, Mariona, Huang, Rae-Chi, Hummel, Sandra, Just, Allan C., Kajantie, Eero, Lahti, Jari, Lawlor, Deborah, Räikkönen, Katri, Järvelin, Marjo-Riitta, Felix, Janine F., Sebert, Sylvain

“…Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models…”
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Longitudinal associations of DNA methylation and sleep in children: a meta-analysis by Sammallahti, Sara, Koopman-Verhoeff, M Elisabeth, Binter, Anne-Claire, Mulder, Rosa H, Cabré-Riera, Alba, Kvist, Tuomas, Malmberg, Anni L K, Pesce, Giancarlo, Plancoulaine, Sabine, Heiss, Jonathan A, Rifas-Shiman, Sheryl L, Röder, Stefan W, Starling, Anne P, Wilson, Rory, Guerlich, Kathrin, Haftorn, Kristine L, Page, Christian M, Luik, Annemarie I, Tiemeier, Henning, Felix, Janine F, Raikkonen, Katri, Lahti, Jari, Relton, Caroline L, Sharp, Gemma C, Waldenberger, Melanie, Grote, Veit, Heude, Barbara, Annesi-Maesano, Isabella, Hivert, Marie-France, Zenclussen, Ana C, Herberth, Gunda, Dabelea, Dana, Grazuleviciene, Regina, Vafeiadi, Marina, Håberg, Siri E, London, Stephanie J, Guxens, Mònica, Richmond, Rebecca C, Cecil, Charlotte A M

“…Sleep is important for healthy functioning in children. Numerous genetic and environmental factors, from conception onwards, may influence this phenotype…”
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Training a model for estimating leukocyte composition using whole-blood DNA methylation and cell counts as reference by Heiss, Jonathan A, Breitling, Lutz P, Lehne, Benjamin, Kooner, Jaspal S, Chambers, John C, Brenner, Hermann

“…Whole-blood DNA methylation depends on the underlying leukocyte composition and confounding hereby is a major concern in epigenome-wide association studies…”
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Between-array normalization for 450K data by Heiss, Jonathan A, Brenner, Hermann

“…The Illumina Infinium HumanMethylation450 BeadChip is frequently used in epigenetic research. Besides quantile normalization there is currently no standard…”
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Prenatal lead exposure and cord blood DNA methylation in PROGRESS: an epigenome-wide association study by Heiss, Jonathan A, Téllez-Rojo, Martha M, Estrada-Gutiérrez, Guadalupe, Schnaas, Lourdes, Amarasiriwardena, Chitra, Baccarelli, Andrea A, Wright, Robert O, Just, Allan C

“…The effects of prenatal lead exposure on child development include impaired growth and cognitive function. DNA methylation might be involved in the underlying…”
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Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood by Schöttker, Ben, Zhang, Yan, Heiss, Jonathan A., Butterbach, Katja, Jansen, Eugène H. J. M., Bewerunge-Hudler, Melanie, Saum, Kai-Uwe, Holleczek, Bernd, Brenner, Hermann

“…Long‐lasting oxidative stress exposure may lead to relatively stable epigenetic modifications of the DNA in order to activate anti‐oxidative defence…”
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