Search Results - "Heise, Ruth"

Comprehensive molecular characterization of microneedling therapy in a human three-dimensional skin model by Schmitt, Laurenz, Marquardt, Yvonne, Amann, Philipp, Heise, Ruth, Huth, Laura, Wagner-Schiffler, Sylvia, Huth, Sebastian, Baron, Jens-Malte

“…Microneedling therapy is a widely used technique in dermatology. However, little is known about the underlying molecular effects of this therapy on…”
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Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer by Huth, Sebastian, Huth, Laura, Heise, Ruth, Marquardt, Yvonne, Lopopolo, Linda, Piecychna, Marta, Boor, Peter, Fingerle-Rowson, Günter, Kapurniotu, Aphrodite, Yazdi, Amir S., Bucala, Richard, Bernhagen, Jürgen, Baron, Jens Malte

“…Non-melanoma skin cancer (NMSC) is the most common cancer in Caucasians worldwide. We investigated the pathophysiological role of MIF and its homolog D-DT in…”
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Effects of a ceramide‐containing water‐in‐oil ointment on skin barrier function and allergen penetration in an IL‐31 treated 3D model of the disrupted skin barrier by Huth, Sebastian, Schmitt, Laurenz, Marquardt, Yvonne, Heise, Ruth, Lüscher, Bernhard, Amann, Philipp M., Baron, Jens M.

“…Atopic dermatitis (AD) is a chronically relapsing, pruritic inflammation of the skin with dryness and disturbed skin barrier function. Recently, we established…”
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Interferon Alpha Signalling and Its Relevance for the Upregulatory Effect of Transporter Proteins Associated with Antigen Processing (TAP) in Patients with Malignant Melanoma by Heise, Ruth, Amann, Philipp M, Ensslen, Silke, Marquardt, Yvonne, Czaja, Katharina, Joussen, Sylvia, Beer, Daniel, Abele, Rupert, Plewnia, Gabriele, Tampé, Robert, Merk, Hans F, Hermanns, Heike M, Baron, Jens M

“…Interferon alpha (IFNα) is routinely used in the clinical practice for adjuvant systemic melanoma therapy. Understanding the molecular mechanism of IFNα…”
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Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts by Wiederholt, Tonio, Heise, Ruth, Skazik, Claudia, Marquardt, Yvonne, Joussen, Sylvia, Erdmann, Kati, Schröder, Henning, Merk, Hans F., Baron, Jens Malte

“…:  Topical application of pantothenate is widely used in clinical practice for wound healing. Previous studies identified a positive effect of pantothenate on…”
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Active Transport of Contact Allergens and Steroid Hormones in Epidermal Keratinocytes is Mediated by Multidrug Resistance Related Proteins by Heise, Ruth, Skazik, Claudia, Rodriguez, Felipe, Stanzel, Sven, Marquardt, Yvonne, Joussen, Sylvia, Wendel, Andreas F., Wosnitza, Melanie, Merk, Hans F., Baron, Jens M.

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MMP-3 plays a major role in calcium pantothenate-promoted wound healing after fractional ablative laser treatment by Huth, Sebastian, Huth, Laura, Marquardt, Yvonne, Cheremkhina, Maria, Heise, Ruth, Baron, Jens Malte

“…Ablative fractional laser treatment leads to a loss of matrix metalloproteinase-3 (MMP-3) expression; therefore, in the present in vitro study, we addressed…”
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Expression of CYP1A1, CYP1B1 and IL-1β in PBMCs and skin samples of PCB exposed individuals by Leijs, Marike M., Esser, André, Amann, Philipp M., Schettgen, Thomas, Heise, Ruth, Fietkau, Katharina, Gube, Monika, Merk, Hans F., Kraus, Thomas, Baron, Jens M.

“…Polychlorinated biphenyls (PCBs) are well- known man-made persistent environmental pollutants and endocrine disruptors. As a result of mass production in the…”
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Characterization of a novel standardized human three-dimensional skin wound healing model using non-sequential fractional ultrapulsed CO2 laser treatments by Marquardt, Yvonne, Amann, Philipp M., Heise, Ruth, Czaja, Katharina, Steiner, Timm, Merk, Hans F., Skazik-Voogt, Claudia, Baron, Jens M.

“…Background and Objective At present, there is no standardized in vitro human skin model for wound healing. Therefore, our aim was to establish and characterize…”
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Bifonazole Exerts Anti-Inflammatory Effects in Human Three-Dimensional Skin Equivalents after UVB or Histamine Challenge by Huth, Laura, Marquardt, Yvonne, Heise, Ruth, Fietkau, Katharina, Becker, Norbert-Heinz, Huth, Sebastian, Baron, Jens Malte

“…In addition to its role as a broad-spectrum imidazole antifungal drug, data from animal models as well as human clinical trials also demonstrated an…”
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Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen‐presenting cells in skin by Brocks, Tania, Fedorchenko, Oleg, Schliermann, Nicola, Stein, Astrid, Moll, Ute M., Seegobin, Seth, Dewor, Manfred, Hallek, Michael, Marquardt, Yvonne, Fietkau, Katharina, Heise, Ruth, Huth, Sebastian, Pfister, Herbert, Bernhagen, Juergen, Bucala, Richard, Baron, Jens M., Fingerle‐Rowson, Guenter

“…ABSTRACT The response of the skin to harmful environmental agents is shaped decisively by the status of the immune system. Keratinocytes constitutively express…”
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Synthesis of a Sulfonimidamide-Based Analog of Tasisulam and Its Biological Evaluation in the Melanoma Cell Lines SKMel23 and A375 by Steinkamp, Anne-Dorothee, Schmitt, Laurenz, Chen, Xiaoyun, Fietkau, Katharina, Heise, Ruth, Baron, Jens M, Bolm, Carsten

“…Tasisulam is a promising antitumor agent with complex pharmacology, which is used as an antiproliferative agent in patients with metastatic melanoma and other…”
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Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models by Amann, Philipp M., Marquardt, Yvonne, Steiner, Timm, Hölzle, Frank, Skazik-Voogt, Claudia, Heise, Ruth, Baron, Jens M.

“…Clinical experiences with non-ablative fractional erbium glass laser therapy have demonstrated promising results for dermal remodelling and for the indications…”
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Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial by Heise, Ruth, Schmitt, Laurenz, Huth, Laura, Krings, Laura, Kluwig, David, Katsoulari, Krista-Vasiliki, Steiner, Timm, Hölzle, Frank, Baron, Jens Malte, Huth, Sebastian

“…Background: Laser therapy with an ablative CO 2 laser is a prominent treatment option for photo-damaged skin. The healing process and therefore the success of…”
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Novel Human Full-Thickness Three-Dimensional Nonkeratinized Mucous Membrane Model for Pharmacological Studies in Wound Healing by Schmitt, Laurenz, Marquardt, Yvonne, Heise, Ruth, von Felbert, Verena, Amann, Philipp M, Huth, Laura, Steiner, Timm, Hölzle, Frank, Huth, Sebastian, Baron, Jens Malte

“…Efforts are increasingly aiming to develop in vitro models that can provide effective alternatives to in vivo experiments. The main aim of this study was the…”
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Downregulation of STRA6 Expression in Epidermal Keratinocytes Leads to Hyperproliferation-Associated Differentiation in Both In Vitro and In Vivo Skin Models by Skazik, Claudia, Amann, Philipp M., Heise, Ruth, Marquardt, Yvonne, Czaja, Katharina, Kim, Arianna, Rühl, Ralph, Kurschat, Peter, Merk, Hans F., Bickers, David R., Baron, Jens M.

“…Retinoids are known to affect skin cell proliferation and differentiation and are key molecules that target retinoid and retinoic acid receptors (RXRs and…”
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Inter-α-trypsin inhibitor heavy chain 5 (ITIH5) is overexpressed in inflammatory skin diseases and affects epidermal morphology in constitutive knockout mice and murine 3D skin models by Huth, Sebastian, Heise, Ruth, Vetter-Kauczok, Claudia S., Skazik, Claudia, Marquardt, Yvonne, Czaja, Katharina, Knüchel, Ruth, Merk, Hans F., Dahl, Edgar, Baron, Jens M.

“…Inter‐α‐trypsin inhibitors are protease inhibitors that are thought to be important regulators in various acute‐phase processes. They are composed of one light…”
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Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO 2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial by Heise, Ruth, Schmitt, Laurenz, Huth, Laura, Krings, Laura, Kluwig, David, Katsoulari, Krista-Vasiliki, Steiner, Timm, Hölzle, Frank, Baron, Jens Malte, Huth, Sebastian

“…Laser therapy with an ablative CO laser is a prominent treatment option for photo-damaged skin. The healing process and therefore the success of a laser can be…”
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Characterization of a novel standardized human three‐dimensional skin wound healing model using non‐sequential fractional ultrapulsed CO 2 laser treatments by Marquardt, Yvonne, Amann, Philipp M., Heise, Ruth, Czaja, Katharina, Steiner, Timm, Merk, Hans F., Skazik‐Voogt, Claudia, Baron, Jens M.

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Characterization of a novel standardized human three-dimensional skin wound healing model using non-sequential fractional ultrapulsed CO sub(2) laser treatments by Marquardt, Yvonne, Amann, Philipp M, Heise, Ruth, Czaja, Katharina, Steiner, Timm, Merk, Hans F, Skazik-Voogt, Claudia, Baron, Jens M

“…Background and Objective At present, there is no standardized in vitro human skin model for wound healing. Therefore, our aim was to establish and characterize…”
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