Search Results - "Heirwegh, K P"

Testing and characterizing enzymes and membrane-bound carrier proteins acting on amphipathic ligands in the presence of bilayer membrane material and soluble binding protein : application to the uptake of oleate into isolated cells by HEIRWEGH, K. P. M, MEUWISSEN, J. A. T. P

“…1. A multiphasic modelling approach [Heirwegh, Meuwissen, Vermeir & De Smedt (1988) Biochem. J. 254, 101-108] is applied to systems containing poorly…”
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Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor by Van Roy, F P, Heirwegh, K P

“…1. Conjugated bilirubin is conveniently determined by coupling with the diazonium salt of ethyl anthranilate. 2. This method has been used in the development…”
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Bilirubin conjugates in bile of man and rat in the normal state and in liver disease by Fevery, J, Van Damme, B, Michiels, R, De Groote, J, Heirwegh, K P

“…Conjugates of bilirubin were studied in normal bile of man and rat, and in bile of liver patients. In general human bile was obtained by duodenal intubation…”
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Principles of a competitive binding assay for the study of the interactions of poorly water-soluble ligands with their soluble binding partners. Application to bilirubin with the use of Sephadex G-10 as a competitive adsorbent by Meuwissen, J A, Kinnaert, M, Michiels, G, Heirwegh, K P

“…1. A generally applicable method is described for obtaining experimental data on the interactions between a poorly water-soluble ligand and soluble binding…”
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Enzymic transfer of glucose and xylose from uridine diphosphate glucose and uridine diphosphate xylose to bilirubin by untreated and digitonin-activated preparations from rat liver by Fevery, J, Leroy, P, Heirwegh, K P

“…1. Digitonin-treated and untreated homogenates, cell extracts and washed microsomal preparations from liver of Wistar R rats are capable of transferring sugar…”
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Excretion in dog bile of glucose and xylose conjugates of bilirubin by Fevery, J, Van Hees, G P, Leroy, P, Compernolle, F, Heirwegh, K P

“…1. T.l.c. with neutral solvent systems of ethyl anthranilate azopigments derived from bile of man, dog and rat revealed pronounced species variation. The less…”
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Assay and properties of digitonin-activated bilirubin uridine diphosphate glucuronyltransferase from rat liver by Heirwegh, K. P. M., Van De Vijver, M., Fevery, J.

“…1. The bilirubin UDP-glucuronyltransferase assay described by Van Roy & Heirwegh (1968) has been improved. 2. Extraction of final azo-derivatives is rendered…”
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Mass-spectrometric structure elucidation of dog bile azopigments as the acyl glycosides of glucopyranose and xylopyranose by Compernolle, F, Van Hees, G P, Fevery, J, Heirwegh, K P

“…1. The structures of the alpha(2)- and alpha(3)-azopigments, prepared by diazotization of dog bile with ethyl anthranilate, were shown by mass spectrometry and…”
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Mass-spectrometric study of the azopigments obtained from bile pigments with diazotized ethyl anthranilate by Compernolle, F, Jansen, F H, Heirwegh, K P

“…The structures of some azopigments obtained by diazotization of conjugated and unconjugated bile pigments with diazotized ethyl anthranilate were studied by…”
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Structures of bilirubin conjugates synthesized in vitro from bilirubin and uridine diphosphate glucuronic acid, uridine diphosphate glucose or uridine diphosphate xylose by preparations from rat liver by Fevery, J, Leroy, P, Van de Vijver, M, Heirwegh, K P

“…1. In incubation mixtures containing digitonin-activated or untreated preparations from rat liver, albumin-solubilized bilirubin as the acceptor substrate and…”
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Unconjugated hyperbilirubinaemia in achalasia by Fevery, J., Heirwegh, K. P. M., De Groote, J.

“…Moderate unconjugated hyperbilirubinaemia decreasing after pneumatic dilatation of the gastrooesophageal sphincter, so permitting a normal amount of food to be…”
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Hepatocyte transplantation for enzyme deficiency disease in congenic rats by Vroemen, J P, Buurman, W A, Heirwegh, K P, van der Linden, C J, Kootstra, G

“…Long-term effects of hepatocyte transplantation (HTX) in the treatment of enzyme deficiency disease were studied. Congenic enzyme-deficient (R/APfd-j/j) and…”
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Synthesis, chromatographic purification, and analysis of isomers of biliverdin IX and bilirubin IX by Heirwegh, K P, Blanckaert, N, Van Hees, G

“…Neutral solvent systems were developed to isolate the alpha, beta, gamma, and delta isomers of biliverdin IX dimethyl ester by TLC. The individual free acids…”
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Interaction of 7-n-alkoxycoumarins with cytochrome P-4502 and their partitioning into liposomal membranes : assessment of methods for determination of membrane partition coefficients by VERMEIR, M, BOENS, N, HEIRWEGH, K. P. M

“…A study was made of the binding of 7-ethoxy-, 7-n-propoxy- and 7-n-pentoxy-coumarin to cytochrome P-450(2) reconstituted into large unilamellar liposomes…”
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The error in the Michaelis-Menten equation when substrate depletion by binding to the enzyme is not taken into account by HEIRWEGH, K. P. M, VERMEIR, M

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A NEW DIAZO REAGENT FOR SPECIFIC STAINING OF CONJUGATED BILIRUBIN IN TISSUE SECTIONS by DESMET, V. J, BULLENS, A.-M, DE GROOTE, J, HEIRWEGH, K. P. M

“…A new technique is presented for the specific histochemical demonstration of conjugated bilirubin in tissue sections, using the diazonium salt of…”
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Modelling of interaction of basic lipophilic ligands with cytochrome P-450 reconstituted in liposomes. Determination of membrane partition coefficients of S-(-)-nicotine and N,N-diethylaniline from spectral binding studies and fluorescence quenching by Vermeir, M, Boens, N, Heirwegh, K P

“…The spectral interaction of N,N-diethylaniline and S-(-)-nicotine with cytochrome P450IIB4 reconstituted into large unilamellar vesicles could properly be…”
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Activation in vitro and solubilization of glucuronyltransferase (assayed with bilirubin as acceptor) with digitonin by Heirwegh, K P, Meuwissen, J A

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Thyroid hormones and the hepatic handling of bilirubin. I. Effects of hypothyroidism and hyperthyroidism on the hepatic transport of bilirubin mono- and diconjugates in the Wistar rat by Van Steenbergen, W, Fevery, J, De Vos, R, Leyten, R, Heirwegh, K P, De Groote, J

“…The effects of thyroidectomy and of thyroid hormone administration on the hepatic transport of endogenous bilirubin were investigated in the Wistar R/APfd rat…”
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Bilirubin-binding properties of plasma and liver cytosol preparations from rats by Meuwissen, J A, Fevery, J, Heirwegh, K P

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