Search Results - "Heinz, Werner J."

Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016 by Ullmann, Andrew J., Schmidt-Hieber, Martin, Bertz, Hartmut, Heinz, Werner J., Kiehl, Michael, Krüger, William, Mousset, Sabine, Neuburger, Stefan, Neumann, Silke, Penack, Olaf, Silling, Gerda, Vehreschild, Jörg Janne, Einsele, Hermann, Maschmeyer, Georg

“…Infectious complications after allogeneic haematopoietic stem cell transplantation (allo-HCT) remain a clinical challenge. This is a guideline provided by the…”
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Phase 1B Study of the Pharmacokinetics and Safety of Posaconazole Intravenous Solution in Patients at Risk for Invasive Fungal Disease by MAERTENS, Johan, CORNELY, Oliver A, ULLMANN, Andrew J, HEINZ, Werner J, KRISHNA, Gopal, PATINO, Hernando, CACERES, Maria, KARTSONIS, Nicholas, WASKIN, Hetty, ROBERTSON, Michael N

“…This was a phase 1B, dose-ranging, multicenter, pharmacokinetics, and safety study of cyclodextrin-based posaconazole intravenous (i.v.) solution administered…”
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Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease by Cornely, Oliver A, Robertson, Michael N, Haider, Shariq, Grigg, Andrew, Geddes, Michelle, Aoun, Mickael, Heinz, Werner J, Raad, Issam, Schanz, Urs, Meyer, Ralf G, Hammond, Sarah P, Mullane, Kathleen M, Ostermann, Helmut, Ullmann, Andrew J, Zimmerli, Stefan, Van Iersel, M L P S, Hepler, Deborah A, Waskin, Hetty, Kartsonis, Nicholas A, Maertens, Johan

“…A two-part (Phase 1B/3), sequential, open-label, multicentre study evaluated the pharmacokinetics (PK) and safety of intravenous (iv) posaconazole given as…”
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Multicenter Comparison of Serum and Whole-Blood Specimens for Detection of Aspergillus DNA in High-Risk Hematological Patients by Springer, Jan, Morton, C O, Perry, Michael, Heinz, Werner J, Paholcsek, Melinda, Alzheimer, Mona, Rogers, T R, Barnes, Rosemary A, Einsele, Hermann, Loeffler, Juergen, White, P Lewis

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Bendamustine, followed by ofatumumab and ibrutinib in chronic lymphocytic leukemia (CLL2-BIO): primary endpoint analysis of a multicenter, open-label phase-II trial by Cramer, Paula, Tresckow, Julia V, Robrecht, Sandra, Bahlo, Jasmin, Fürstenau, Moritz, Langerbeins, Petra, Pflug, Natali, Al-Sawaf, Othman, Heinz, Werner J, Vehling-Kaiser, Ursula, Dürig, Jan, Tausch, Eugen, Hensel, Manfred, Sasse, Stephanie, Fink, Anna-Maria, Fischer, Kirsten, Kreuzer, Karl-Anton, Böttcher, Sebastian, Ritgen, Matthias, Kneba, Michael, Wendtner, Clemens-Martin, Stilgenbauer, Stephan, Eichhorst, Barbara, Hallek, Michael

“…The introduction of targeted agents has revolutionized the treatment of chronic lymphocytic leukemia but only few patients achieve complete remissions and…”
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Clinical evidence for caspofungin monotherapy in the first-line and salvage therapy of invasive Aspergillus infections by Heinz, Werner J., Buchheidt, Dieter, Ullmann, Andrew J.

“…Summary In 2001, caspofungin received market authorisation by the FDA and EMA and is globally licensed for several indications, including candidiasis,…”
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Intravenous and tablet formulation of posaconazole in antifungal therapy and prophylaxis: A retrospective, non-interventional, multicenter analysis of hematological patients treated in tertiary-care hospitals by Heimann, Sebastian M., Penack, Olaf, Heinz, Werner J., Rachow, Tobias, Egerer, Gerlinde, Kessel, Johanna, Claßen, Annika Y., Vehreschild, Jörg Janne

“…•Safety, efficacy, and feasibility of antifungal prophylaxis and therapy of IFDs with novel posaconazole formulations could be demonstrated.•Stable…”
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Primary prophylaxis of invasive fungal infections in patients with hematologic malignancies. Recommendations of the Infectious Diseases Working Party of the German Society for Haematology and Oncology by Cornely, Oliver A, Bohme, Angelika, Buchheidt, Dieter, Einsele, Hermann, Heinz, Werner J, Karthaus, Meinolf, Krause, Stefan W, Kruger, William, Maschmeyer, Georg, Penack, Olaf, Ritter, Jorg, Ruhnke, Markus, Sandherr, Michael, Sieniawski, Michal, Vehreschild, Jorg-Janne, Wolf, Hans-Heinrich, Ullmann, Andrew J

“…1 Klinik I für Innere Medizin, Klinikum der Universität Köln 2 Zentrum für Klinische Studien (01KN0706), Köln 3 Onkologikum Frankfurt am Museumsufer, Frankfurt…”
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Viral encephalitis after allogeneic stem cell transplantation: a rare complication with distinct characteristics of different causative agents by SCHMIDT-HIEBER, Martin, SCHWENDER, Julie, NEUBURGER, Stefan, THIEL, Eckhard, BLAU, Igor W, HEINZ, Werner J, ZABELINA, Tatjana, KÜHL, Jorn S, MOUSSET, Sabine, SCHÜTTRUMPF, Silke, JUNGHANSS, Christian, SILLING, Gerda, BASARA, Nadezda

“…Limited data are available on characteristics of viral encephalitis in patients after allogeneic stem cell transplantation. We analyzed 2,628 patients after…”
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Population Pharmacokinetics of Liposomal Amphotericin B and Caspofungin in Allogeneic Hematopoietic Stem Cell Recipients by WÜRTHWEIN, Gudrun, YOUNG, Charlotte, BOOS, Joachim, SILLING, Gerda, GROLL, Andreas H, LANVERS-KAMINSKY, Claudia, HEMPEL, Georg, TRAME, Mirjam N, SCHWERDTFEGER, Rainer, OSTERMANN, Helmut, HEINZ, Werner J, CORNELY, Oliver A, KOLVE, Hedwig

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High-performance liquid chromatographic method for the determination of sorafenib in human serum and peritoneal fluid by Heinz, Werner J., Kahle, Kathrin, Helle-Beyersdorf, Annegret, Schirmer, Diana, Lenker, Ulrike, Keller, Daniela, Langmann, Peter, Klinker, Hartwig

“…Purpose Sorafenib is recommended for therapy of advanced hepatocellular carcinoma and renal cell carcinoma. Preclinical data indicate a relation between dose…”
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An Overview of Systematic Reviews of Polymerase Chain Reaction (PCR) for the Diagnosis of Invasive Aspergillosis in Immunocompromised People: A Report of the Fungal PCR Initiative (FPCRI)-An ISHAM Working Group by Cruciani, Mario, White, P Lewis, Barnes, Rosemary A, Loeffler, Juergen, Donnelly, J Peter, Rogers, Thomas R, Heinz, Werner J, Warris, Adilia, Morton, Charles Oliver, Lengerova, Martina, Klingspor, Lena, Sendid, Boualem, Lockhart, Deborah E A

“…This overview of reviews (i.e., an umbrella review) is designed to reappraise the validity of systematic reviews (SRs) and meta-analyses related to the…”
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Simultaneous Determination of Voriconazole and Posaconazole Concentrations in Human Plasma by High-Performance Liquid Chromatography by KAHLE, Kathrin, LANGMANN, Peter, SCHIRMER, Diana, LENKER, Ulrike, KELLER, Daniela, HELLE, Annegret, KLINKER, Hartwig, HEINZ, Werner J

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Relevance of Timing for Determination of Posaconazole Plasma Concentrations by HEINZ, Werner J, ZIRKEL, Janina, KUHN, Anna, SCHIRMER, Diana, LENKER, Ulrike, KELLER, Daniela, KLINKER, Hartwig

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Randomized Comparison of Safety and Pharmacokinetics of Caspofungin, Liposomal Amphotericin B, and the Combination of Both in Allogeneic Hematopoietic Stem Cell Recipients by GROLL, Andreas H, SILLING, Gerda, GAMMELIN, Sibylle, CORNELY, Oliver A, WUERTHWEIN, Gudrun, YOUNG, Charlotte, SCHWERDTFEGER, Rainer, OSTERMANN, Helmut, HEINZ, Werner J, GERSS, Joachim, KOLVE, Hedwig, LANVERS-KAMINSKY, Claudia, VIEIRA PINHEIRO, João Paulo

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Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system by Schwartz, Stefan, Cornely, Oliver A, Hamed, Kamal, Marty, Francisco M, Maertens, Johan, Rahav, Galia, Herbrecht, Raoul, Heinz, Werner J

“…The incidence of invasive fungal diseases (IFDs) with central nervous system (CNS) involvement is increasing due to the rising numbers of immunocompromised…”
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Combination antifungal therapy for invasive aspergillosis: a randomized trial by Marr, Kieren A, Schlamm, Haran T, Herbrecht, Raoul, Rottinghaus, Scott T, Bow, Eric J, Cornely, Oliver A, Heinz, Werner J, Jagannatha, Shyla, Koh, Liang Piu, Kontoyiannis, Dimitrios P, Lee, Dong-Gun, Nucci, Marcio, Pappas, Peter G, Slavin, Monica A, Queiroz-Telles, Flavio, Selleslag, Dominik, Walsh, Thomas J, Wingard, John R, Maertens, Johan A

“…Invasive aspergillosis (IA) is associated with poor outcomes in patients with hematologic malignancies (HMs) and hematopoietic cell transplantation (HCT)…”
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Primary prophylaxis of invasive fungal diseases in patients with haematological malignancies: 2022 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO) by Stemler, Jannik, Mellinghoff, Sibylle C, Khodamoradi, Yascha, Sprute, Rosanne, Classen, Annika Y, Zapke, Sonja E, Hoenigl, Martin, Krause, Robert, Schmidt-Hieber, Martin, Heinz, Werner J, Klein, Michael, Koehler, Philipp, Liss, Blasius, Koldehoff, Michael, Buhl, Christoph, Penack, Olaf, Maschmeyer, Georg, Schalk, Enrico, Lass-Flörl, Cornelia, Karthaus, Meinolf, Ruhnke, Markus, Cornely, Oliver A, Teschner, Daniel

“…Abstract Patients with haematological malignancies (HM) are at high risk of developing invasive fungal disease (IFD) with high morbidity and attributable…”
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Invasive fungal diseases in patients with new diagnosed acute lymphoblastic leukaemia by Gründahl, Marie, Wacker, Beate, Einsele, Hermann, Heinz, Werner J.

“…Summary Background Patients with acute leukaemia have a high incidence of fungal infections. This has primarily been shown in acute myeloid leukaemia and is…”
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Empiric vs Preemptive Antifungal Strategy in High-Risk Neutropenic Patients on Fluconazole Prophylaxis: A Randomized Trial of the European Organization for Research and Treatment of Cancer by Maertens, Johan, Lodewyck, Tom, Donnelly, J Peter, Chantepie, Sylvain, Robin, Christine, Blijlevens, Nicole, Turlure, Pascal, Selleslag, Dominik, Baron, Frédéric, Aoun, Mickael, Heinz, Werner J, Bertz, Hartmut, Ráčil, Zdeněk, Vandercam, Bernard, Drgona, Lubos, Coiteux, Valerie, Llorente, Cristina Castilla, Schaefer-Prokop, Cornelia, Paesmans, Marianne, Ameye, Lieveke, Meert, Liv, Cheung, Kin Jip, Hepler, Deborah A, Loeffler, Jürgen, Barnes, Rosemary, Marchetti, Oscar, Verweij, Paul, Lamoth, Frederic, Bochud, Pierre-Yves, Schwarzinger, Michael, Cordonnier, Catherine

“…Empiric antifungal therapy is considered the standard of care for high-risk neutropenic patients with persistent fever. The impact of a preemptive,…”
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